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KIDINS220 [cytosol]
Stable Identifier
R-HSA-169880
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
ARMS/KIDINS220 protein
Locations in the PathwayBrowser
Expand all
Signal Transduction (Homo sapiens)
Signaling by Receptor Tyrosine Kinases (Homo sapiens)
Signaling by NTRKs (Homo sapiens)
Signaling by NTRK1 (TRKA) (Homo sapiens)
Signalling to ERKs (Homo sapiens)
Prolonged ERK activation events (Homo sapiens)
ARMS-mediated activation (Homo sapiens)
ARMS is phosphorylated by active TrkA receptor (Homo sapiens)
Active TrkA receptor:ARMS:Crk complex [plasma membrane] (Homo sapiens)
ARMS:Crk [cytosol] (Homo sapiens)
KIDINS220 [cytosol] (Homo sapiens)
ARMS:Crk complex binds to active TrkA receptor (Homo sapiens)
ARMS:Crk [cytosol] (Homo sapiens)
KIDINS220 [cytosol] (Homo sapiens)
Active TrkA receptor:ARMS:Crk complex [plasma membrane] (Homo sapiens)
ARMS:Crk [cytosol] (Homo sapiens)
KIDINS220 [cytosol] (Homo sapiens)
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Homo sapiens)
Signaling by Rho GTPases (Homo sapiens)
RHO GTPase cycle (Homo sapiens)
RND1 GTPase cycle (Homo sapiens)
RND1 binds effectors (Homo sapiens)
RND1 effectors [cytosol] (Homo sapiens)
KIDINS220 [cytosol] (Homo sapiens)
RND1:GTP:RND1 effectors [plasma membrane] (Homo sapiens)
RND1 effectors [cytosol] (Homo sapiens)
KIDINS220 [cytosol] (Homo sapiens)
RND2 GTPase cycle (Homo sapiens)
RND2 binds effectors (Homo sapiens)
RND2 effectors [cytosol] (Homo sapiens)
KIDINS220 [cytosol] (Homo sapiens)
RND2:GTP:RND2 effectors [plasma membrane] (Homo sapiens)
RND2 effectors [cytosol] (Homo sapiens)
KIDINS220 [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q9ULH0 KIDINS220
Gene Names
KIDINS220, ARMS, KIAA1250
Chain
chain:1-1771
Reference Genes
BioGPS Gene:57498 KIDINS220
COSMIC (genes):KIDINS220 KIDINS220
CTD Gene:57498 KIDINS220
dbSNP Gene:57498 KIDINS220
ENSEMBL:ENSG00000134313 KIDINS220
ENSEMBL_homo_sapiens_GENE:ENSG00000134313.17 KIDINS220
HGNC:29508 KIDINS220
KEGG Gene (Homo sapiens):57498 KIDINS220
Monarch:57498 KIDINS220
NCBI Gene:57498 KIDINS220
OMIM:615759 KIDINS220
UCSC:Q9ULH0 KIDINS220
Reference Transcript
RefSeq:NM_020738.2 KIDINS220
Other Identifiers
11743331_a_at
11745889_a_at
11746232_a_at
11750597_a_at
16894235
212162_PM_at
212162_at
212163_PM_at
212163_at
214932_PM_at
214932_at
2539528
2539529
2539530
2539531
2539532
2539535
2539537
2539539
2539546
2539548
2539551
2539554
2539555
2539557
2539558
2539559
2539560
2539561
2539565
2539569
2539571
2539572
2539573
2539574
2539576
2539577
2539578
2539579
2539580
2539581
2539582
2539583
2539585
2539586
2539589
2539591
2539592
2539593
2539595
2539596
2539597
2539600
2539602
3363691
39163_at
57498
8050128
A_23_P131747
A_24_P97145
GE505854
GE53851
GO:0001701
GO:0005515
GO:0005768
GO:0005770
GO:0005829
GO:0007399
GO:0010976
GO:0016020
GO:0019887
GO:0023052
GO:0030154
GO:0030165
GO:0031410
GO:0032991
GO:0038180
GO:0043226
GO:0048813
GO:0048856
GO:0098772
GO:1990090
Hs.9873.0.S1_3p_at
Hs.9873.0.S2_3p_at
Hs.9873.1.S1_3p_at
ILMN_1679232
PH_hs_0001022
TC02001555.hg
Participates
as a candidate of
RND2 effectors [cytosol] (Homo sapiens)
RND1 effectors [cytosol] (Homo sapiens)
as a component of
ARMS:Crk [cytosol] (Homo sapiens)
Other forms of this molecule
p-Y1095-KIDINS220 [cytosol]
Inferred To
KIDINS220 [cytosol]
(Bos taurus)
KIDINS220 [cytosol]
(Canis familiaris)
KIDINS220 [cytosol]
(Gallus gallus)
KIDINS220 [cytosol]
(Sus scrofa)
kidins220 [cytosol]
(Xenopus tropicalis)
Kidins220 [cytosol]
(Mus musculus)
Kidins220 [cytosol]
(Rattus norvegicus)
kidins220b [cytosol]
(Danio rerio)
Cross References
RefSeq
NP_065789.1
OpenTargets
ENSG00000134313
GeneCards
Q9ULH0
HPA
ENSG00000134313-KIDINS220
Ensembl
ENSG00000134313
,
ENSP00000510510
,
ENSP00000319947
,
ENST00000256707
,
ENSP00000418974
,
ENST00000685097
,
ENSP00000256707
,
ENST00000473731
,
ENST00000319688
PRO
Q9ULH0
Pharos - Targets
Q9ULH0
Orphanet
24646
Interactors (2)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P21802 FGFR2
20
FGFR2 IIIa TM [extracellular region]
(R-HSA-8851703)
FGFR2 [plasma membrane]
(R-HSA-2023840)
FGFR2(22-767)-CCDC6(102-474) fusion [plasma membrane]
(R-HSA-8853137)
FGFR2(2-822)-CIT(927-2027) fusion [plasma membrane]
(R-HSA-8853154)
FGFR2(22-768)-BICC1(80-974) fusion [plasma membrane]
(R-HSA-8853123)
FGFR2(22-767)-AHCYL1(108-530) fusion [plasma membrane]
(R-HSA-8853158)
FGFR2(22-767)-OFD1(38-1012) fusion [plasma membrane]
(R-HSA-8853150)
FGFR2(22-767)-CASP7(1-303) fusion [plasma membrane]
(R-HSA-8853153)
FGFR2(22-767)-AFF3(292-1226) fusion [plasma membrane]
(R-HSA-8853139)
FGFR2(22-767)-CCAR(51-923) fusion [plasma membrane]
(R-HSA-8853159)
FGFR2 N549H [plasma membrane]
(R-HSA-2033296)
FGFR2 N549K [plasma membrane]
(R-HSA-1637910)
FGFR2 K660N [plasma membrane]
(R-HSA-1637905)
FGFR2 K660M [plasma membrane]
(R-HSA-1637902)
FGFR2 K660E [plasma membrane]
(R-HSA-1637900)
FGFR2 S267P [plasma membrane]
(R-HSA-1637920)
FGFR2 L764Hfs*4 [plasma membrane]
(R-HSA-1637908)
FGFR2 W290C [plasma membrane]
(R-HSA-1637929)
p-6Y-FGFR2(22-767)-CCDC6(102-474) fusion [plasma membrane]
(R-HSA-8853134)
p-6Y-FGFR2(22-768)-BICC1(80-974) fusion [plasma membrane]
(R-HSA-8853146)
0.483
2
UniProt:P34925 RYK
1
RYK [plasma membrane]
(R-HSA-3006746)
0.483
2
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