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Go!
I-SMAD [cytosol]
Stable Identifier
R-HSA-173495
Type
Set [DefinedSet]
Species
Homo sapiens
Compartment
cytosol
Locations in the PathwayBrowser
Expand all
Signal Transduction (Homo sapiens)
Signaling by TGFB family members (Homo sapiens)
Signaling by BMP (Homo sapiens)
I-Smad binds to type I receptor, preventing Smad1/5/8 from being activated (Homo sapiens)
BMP:p-BMPR:I-SMAD:SMURF [plasma membrane] (Homo sapiens)
I-SMAD:SMURF [cytosol] (Homo sapiens)
I-SMAD [cytosol] (Homo sapiens)
I-SMAD:SMURF [cytosol] (Homo sapiens)
I-SMAD [cytosol] (Homo sapiens)
I-Smad competes with Co-Smad for R-Smad1/5/8 (Homo sapiens)
I-SMAD [cytosol] (Homo sapiens)
I-SMAD:p-2S-SMAD1/5/8 [cytosol] (Homo sapiens)
I-SMAD [cytosol] (Homo sapiens)
I-Smad competes with R-Smad1/5/8 for type I receptor (Homo sapiens)
BMP2:BMP type II receptor:Phospho-BMP type I receptor:I-SMAD [plasma membrane] (Homo sapiens)
I-SMAD [cytosol] (Homo sapiens)
I-SMAD [cytosol] (Homo sapiens)
Participants
members
SMAD6 [cytosol]
(Homo sapiens)
SMAD7 [cytosol]
(Homo sapiens)
Participates
as a component of
I-SMAD:SMURF [cytosol] (Homo sapiens)
I-SMAD:p-2S-SMAD1/5/8 [cytosol] (Homo sapiens)
BMP2:BMP type II receptor:Phospho-BMP type I receptor:I-SMAD [plasma membrane] (Homo sapiens)
as an input of
I-Smad competes with Co-Smad for R-Smad1/5/8 (Homo sapiens)
I-Smad competes with R-Smad1/5/8 for type I receptor (Homo sapiens)
Inferred To
tag-68 [cytosol]
(Caenorhabditis elegans)
I-SMAD [cytosol]
(Bos taurus)
I-SMAD [cytosol]
(Canis familiaris)
I-SMAD [cytosol]
(Danio rerio)
I-SMAD [cytosol]
(Gallus gallus)
I-SMAD [cytosol]
(Mus musculus)
I-SMAD [cytosol]
(Rattus norvegicus)
I-SMAD [cytosol]
(Sus scrofa)
Dad [cytosol]
(Drosophila melanogaster)
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