Reactome | PSMD9 [nucleoplasm]

PSMD9 [nucleoplasm]

Stable Identifier

R-HSA-174321

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

26S proteasome non-ATPase regulatory subunit 9, 26S proteasome regulatory subunit p27

Locations in the PathwayBrowser

Expand all

Cellular responses to stimuli (Homo sapiens)

- Cellular responses to stress (Homo sapiens)
  - Cellular response to chemical stress (Homo sapiens)
    - KEAP1-NFE2L2 pathway (Homo sapiens)
      - Nuclear events mediated by NFE2L2 (Homo sapiens)
        
        GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 (Homo sapiens)
        
        Ub,pS335,S338,T NFE2L2 is degraded (Homo sapiens)
        
        26S proteasome [nucleoplasm] (Homo sapiens)
        
        PSMD9 [nucleoplasm] (Homo sapiens)

External Reference Information

External Reference

UniProt:O00233 PSMD9

Gene Names

PSMD9

Chain

chain:1-223

Reference Genes

BioGPS Gene:5715 PSMD9

COSMIC (genes):PSMD9 PSMD9

CTD Gene:5715 PSMD9

dbSNP Gene:5715 PSMD9

ENSEMBL:ENSG00000110801 PSMD9

HGNC:9567 PSMD9

KEGG Gene (Homo sapiens):5715 PSMD9

Monarch:5715 PSMD9

NCBI Gene:5715 PSMD9

OMIM:603146 PSMD9

UCSC:O00233 PSMD9

Reference Transcript

Other Identifiers

0007000156

11730205_at

11730206_at

1444_at

16758186

207805_s_at

209334_s_at

3435051

3435052

3435054

3435055

3435056

3435063

3435066

3435069

3435071

3435072

3435073

3435075

3435077

3435079

3435080

36492_at

5715

7959322

AB003177_at

A_23_P203994

A_24_P116017

GE53111

GO:0000165

GO:0000209

GO:0000278

GO:0002223

GO:0002376

GO:0002479

GO:0003674

GO:0003713

GO:0005515

GO:0005575

GO:0005622

GO:0005634

GO:0005654

GO:0005737

GO:0005829

GO:0005838

GO:0006464

GO:0006511

GO:0006520

GO:0006521

GO:0006810

GO:0006950

GO:0007049

GO:0007165

GO:0007267

GO:0008134

GO:0008150

GO:0008540

GO:0009056

GO:0009058

GO:0010972

GO:0015031

GO:0016579

GO:0022607

GO:0030154

GO:0031145

GO:0031146

GO:0032024

GO:0032991

GO:0033209

GO:0034641

GO:0034655

GO:0036388

GO:0038061

GO:0038095

GO:0043161

GO:0043226

GO:0043425

GO:0043488

GO:0043687

GO:0044281

GO:0045893

GO:0046676

GO:0048856

GO:0050852

GO:0055085

GO:0060071

GO:0061418

GO:0065003

GO:0070498

GO:0070682

GO:0090090

GO:0090263

GO:1901990

GO:1902036

HMNXSV003009543

ILMN_1732767

PH_hs_0022459

TC12003259.hg

g12803158_3p_a_at

g4506234_3p_a_at

Participates

as a component of

26S proteasome [nucleoplasm] (Homo sapiens)

Other forms of this molecule

PSMD9 [cytosol]

Inferred To

PSMD9 [nucleoplasm] (Canis familiaris)

PSMD9 [nucleoplasm] (Drosophila melanogaster)

PSMD9 [nucleoplasm] (Sus scrofa)

psmd9 [nucleoplasm] (Danio rerio)

psmD9 [nucleoplasm] (Dictyostelium discoideum)

nas2 [nucleoplasm] (Schizosaccharomyces pombe)

Psmd9 [nucleoplasm] (Mus musculus)

Psmd9 [nucleoplasm] (Rattus norvegicus)

psmd-9 [nucleoplasm] (Caenorhabditis elegans)

Cross References

RefSeq

NP_001248329.1, NP_002804.2

OpenTargets

ENSG00000110801

HPA

ENSG00000110801-PSMD9

GeneCards

O00233

Ensembl

ENST00000537407, ENST00000541212, ENST00000542602, ENSG00000110801, ENSP00000440485, ENSP00000445058, ENSP00000443772

PRO

O00233

Pharos - Targets

O00233

GlyGen

O00233

Interactors (6)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P08887-2 IL6R	1	IL6R-2 [extracellular region] (R-HSA-1067661)	0.611	3
UniProt:P62263 RPS14	2	RPS14 [nucleoplasm] (R-HSA-6790669) RPS14 [cytosol] (R-HSA-72333)	0.611	3
UniProt:Q12933 TRAF2	5	TRAF2 [nucleoplasm] (R-HSA-8862199) K63polyUb-TRAF2 [nucleoplasm] (R-HSA-8862194) K63polyUb-TRAF2 [cytosol] (R-HSA-8862193) PolyUb-TRAF2 [cytosol] (R-HSA-6782848) TRAF2 [cytosol] (R-HSA-66370)	0.556	3
UniProt:P06858 LPL	1	LPL [extracellular region] (R-HSA-174605)	0.556	3
UniProt:Q8N9N5 BANP	1	BANP [nucleoplasm] (R-HSA-3221973)	0.556	3
UniProt:P03952 KLKB1	5	KLKB1(20-638) [plasma membrane] (R-HSA-158385) KLKB1(20-390) [plasma membrane] (R-HSA-158213) KLKB1(391-638) [plasma membrane] (R-HSA-158277) KLKB1(391-638) [extracellular region] (R-HSA-158181) KLKB1(20-390) [extracellular region] (R-HSA-158239)	0.556	3