Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
MAT1A [cytosol]
Stable Identifier
R-HSA-174379
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
MAT I/III
Locations in the PathwayBrowser
Expand all
Metabolism (Homo sapiens)
Biological oxidations (Homo sapiens)
Phase II - Conjugation of compounds (Homo sapiens)
Methylation (Homo sapiens)
MAT1A multimers transfer Ado from ATP to L-Met (Homo sapiens)
MAT1A multimers [cytosol] (Homo sapiens)
MAT1A:K+:2Mg2+ dimer [cytosol] (Homo sapiens)
MAT1A:K+:2Mg2+ [cytosol] (Homo sapiens)
MAT1A [cytosol] (Homo sapiens)
MAT1A:K+:2Mg2+ tetramer [cytosol] (Homo sapiens)
MAT1A:K+:2Mg2+ [cytosol] (Homo sapiens)
MAT1A [cytosol] (Homo sapiens)
Metabolism of amino acids and derivatives (Homo sapiens)
Selenoamino acid metabolism (Homo sapiens)
Metabolism of ingested SeMet, Sec, MeSec into H2Se (Homo sapiens)
SeMet is converted to AdoSeMet by MAT (Homo sapiens)
MAT1A multimers [cytosol] (Homo sapiens)
MAT1A:K+:2Mg2+ dimer [cytosol] (Homo sapiens)
MAT1A:K+:2Mg2+ [cytosol] (Homo sapiens)
MAT1A [cytosol] (Homo sapiens)
MAT1A:K+:2Mg2+ tetramer [cytosol] (Homo sapiens)
MAT1A:K+:2Mg2+ [cytosol] (Homo sapiens)
MAT1A [cytosol] (Homo sapiens)
Sulfur amino acid metabolism (Homo sapiens)
MAT1A multimers transfer Ado from ATP to L-Met (Homo sapiens)
MAT1A multimers [cytosol] (Homo sapiens)
MAT1A:K+:2Mg2+ dimer [cytosol] (Homo sapiens)
MAT1A:K+:2Mg2+ [cytosol] (Homo sapiens)
MAT1A [cytosol] (Homo sapiens)
MAT1A:K+:2Mg2+ tetramer [cytosol] (Homo sapiens)
MAT1A:K+:2Mg2+ [cytosol] (Homo sapiens)
MAT1A [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q00266 MAT1A
Gene Names
MAT1A, AMS1, MATA1
Chain
chain:1-395
Reference Genes
BioGPS Gene:4143 MAT1A
COSMIC (genes):MAT1A MAT1A
CTD Gene:4143 MAT1A
dbSNP Gene:4143 MAT1A
ENSEMBL:ENSG00000151224 MAT1A
ENSEMBL_homo_sapiens_GENE:ENSG00000151224.13 MAT1A
HGNC:6903 MAT1A
KEGG Gene (Homo sapiens):4143 MAT1A
Monarch:4143 MAT1A
NCBI Gene:4143 MAT1A
OMIM:610550 MAT1A
UCSC:Q00266 MAT1A
Reference Transcript
RefSeq:NM_000429.2 MAT1A
RefSeq:XM_005269842.4 MAT1A
Other Identifiers
11724627_a_at
11724628_a_at
16716063
205813_PM_s_at
205813_s_at
32003_at
3297635
3297636
3297637
3297638
3297639
3297640
3297641
3297642
3297643
3297644
3297646
3297649
3297653
3297654
3297656
3297660
3297661
3297662
3297663
3297664
4143
54924_at
7934755
88018_at
A_23_P23996
D49357_at
GE58219
GO:0000166
GO:0003824
GO:0004478
GO:0005515
GO:0005524
GO:0005829
GO:0006520
GO:0006556
GO:0006730
GO:0006790
GO:0009087
GO:0016740
GO:0042802
GO:0046872
GO:0048269
GO:0051289
GO:0065003
HMNXSV003039425
ILMN_1767657
PH_hs_0016112
TC10001462.hg
g4557736_3p_a_at
Participates
as a component of
MAT1A:K+:2Mg2+ [cytosol] (Homo sapiens)
Other forms of this molecule
MAT1A H277Afs*75 [cytosol]
MAT1A V348Gfs*3 [cytosol]
MAT1A K181Vfs*5 [cytosol]
Inferred To
mat1a [cytosol]
(Danio rerio)
mat1a [cytosol]
(Xenopus tropicalis)
MAT1A [cytosol]
(Bos taurus)
MAT1A [cytosol]
(Canis familiaris)
MAT1A [cytosol]
(Dictyostelium discoideum)
MAT1A [cytosol]
(Gallus gallus)
MAT1A [cytosol]
(Mus musculus)
MAT1A [cytosol]
(Plasmodium falciparum)
MAT1A [cytosol]
(Rattus norvegicus)
MAT1A [cytosol]
(Saccharomyces cerevisiae)
MAT1A [cytosol]
(Schizosaccharomyces pombe)
MAT1A [cytosol]
(Sus scrofa)
Cross References
RefSeq
NP_000420.1
,
XP_005269899.1
OpenTargets
ENSG00000151224
IntEnz
2.5.1.6
HPA
ENSG00000151224-MAT1A
GeneCards
Q00266
Ensembl
ENST00000372213
,
ENSG00000151224
,
ENSP00000361287
PRO
Q00266
Pharos - Targets
Q00266
Orphanet
17971
HMDB Protein
HMDBP00418
PDB
6SW6
,
8SWA
,
2OBV
,
6SW5
Interactors (2)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P05067 APP
20
APP(18-770) [trans-Golgi network membrane]
(R-HSA-5229136)
APP-C99 [cytosol]
(R-HSA-9617603)
APP(18-770) [extracellular region]
(R-HSA-49335)
APP(18-770) [platelet alpha granule lumen]
(R-HSA-139835)
APP(18-687) [extracellular region]
(R-HSA-9010033)
APP(688-770) [plasma membrane]
(R-HSA-9010028)
APP(18-770) [Golgi lumen]
(R-HSA-8871509)
APP(18-770) [plasma membrane]
(R-HSA-9010038)
APP(18-671) [endosome lumen]
(R-HSA-5693003)
APP(714-770) [endosome lumen]
(R-HSA-6783325)
APP(712-770) [endosome lumen]
(R-HSA-6783331)
APP(672-770) [endosome lumen]
(R-HSA-9010082)
APP(672-713) [endosome lumen]
(R-HSA-5692993)
APP(672-711) [endosome lumen]
(R-HSA-6783333)
APP(18-770) [endosome lumen]
(R-HSA-5229077)
p-APP [endoplasmic reticulum lumen]
(R-HSA-8957012)
APP [endoplasmic reticulum lumen]
(R-HSA-8956696)
APP(672-711) [extracellular region]
(R-HSA-976740)
APP(672-711) [cytosol]
(R-HSA-877188)
APP(672-713) [extracellular region]
(R-HSA-879340)
0.556
3
UniProt:P42858 HTT
1
HTT [nucleoplasm]
(R-HSA-9023590)
0.556
3
© 2024
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text