Reactome | APOA5 [extracellular region]

APOA5 [extracellular region]

Stable Identifier

R-HSA-174608

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

extracellular region

Synonyms

apoA-V, apolipoprotein A-V

Locations in the PathwayBrowser for interactor UniProt:Q9HB07 MYG1

Expand all

External Reference Information

External Reference

UniProt:Q6Q788 APOA5

Gene Names

APOA5, RAP3, UNQ411/PRO773

Chain

signal peptide:1-23, chain:24-366

Reference Genes

BioGPS Gene:116519 APOA5

COSMIC (genes):APOA5 APOA5

CTD Gene:116519 APOA5

dbSNP Gene:116519 APOA5

ENSEMBL:ENSG00000110243 APOA5

HGNC:17288 APOA5

KEGG:hsa:116519 APOA5

Monarch:116519 APOA5

NCBI Gene:116519 APOA5

OMIM:606368 APOA5

UCSC:Q6Q788 APOA5

Reference Transcript

Other Identifiers

116519

11735047_at

11756672_a_at

16744708

224243_PM_at

224243_at

224244_PM_s_at

224244_s_at

3392958

3392959

3392960

3392961

3392962

3392963

3392964

3392965

3392966

3392967

3392968

7951853

A_23_P75630

GE63051

GO:0005215

GO:0005515

GO:0005543

GO:0005576

GO:0005615

GO:0005768

GO:0005769

GO:0005770

GO:0005788

GO:0005794

GO:0006629

GO:0006641

GO:0006869

GO:0008047

GO:0008201

GO:0008203

GO:0008289

GO:0010898

GO:0010902

GO:0019433

GO:0019899

GO:0031210

GO:0031410

GO:0033344

GO:0033700

GO:0034361

GO:0034364

GO:0034370

GO:0035473

GO:0042157

GO:0042246

GO:0042627

GO:0042632

GO:0043226

GO:0045723

GO:0048260

GO:0048856

GO:0050750

GO:0050996

GO:0051006

GO:0055090

GO:0060228

GO:0060229

GO:0060230

GO:0070325

GO:0070328

GO:0098772

GO:0120020

GO:1903561

HMNXSV003033747

ILMN_1754055

TC11002325.hg

g6707432_3p_at

g6707434_3p_a_at

Participates

as an output of

Expression of APOA5 (Homo sapiens)

This entity regulates

Positively

chylomicron => TG-depleted chylomicron + 50 long-chain fatty acids + 50 diacylglycerols (Homo sapiens)

Other forms of this molecule

APOA5 [endoplasmic reticulum lumen]

p-APOA5 [endoplasmic reticulum lumen]

APOA5 [cytosol]

Inferred To

APOA5 [extracellular region] (Bos taurus)

APOA5 [extracellular region] (Canis familiaris)

APOA5 [extracellular region] (Sus scrofa)

Apoa5 [extracellular region] (Mus musculus)

Apoa5 [extracellular region] (Rattus norvegicus)

Cross References

RefSeq

NP_443200.2, XP_016872658.1, NP_001160070.1

OpenTargets

ENSG00000110243

ENSEMBL

ENSP00000399701, ENST00000227665, ENSP00000445002, ENST00000542499, ENSP00000227665, ENST00000433069

HPA

ENSG00000110243-APOA5

PRO

Q6Q788

Pharos - Targets

Q6Q788

Orphanet

APOA5

GlyGen

Q6Q788

HMDB Protein

HMDBP10986

Interactors (13)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q9BQE4 SELENOS	1	VIMP [endoplasmic reticulum membrane] (R-HSA-8943099)	0.556	3
UniProt:P49638 TTPA	1	TTPA [cytosol] (R-HSA-2980979)	0.556	3
UniProt:Q9HB07 MYG1			0.556	3
UniProt:Q8NDC4 MORN4			0.556	3
UniProt:Q96MX0 CKLF3			0.556	3
UniProt:Q96CM8 ACSF2	1	ACSF2 [mitochondrial matrix] (R-HSA-5696005)	0.556	3
UniProt:Q9NX76 CMTM6	3	CMTM6 [specific granule membrane] (R-HSA-6800916) CMTM6 [plasma membrane] (R-HSA-6806275) CMTM6 [azurophil granule membrane] (R-HSA-6799141)	0.556	3
UniProt:Q9BTV4 TMM43			0.556	3
UniProt:O95393 BMP10	2	BMP10(22-424) [extracellular region] (R-HSA-2396409) BMP10 [extracellular region] (R-HSA-8858374)	0.556	3
UniProt:Q96HH6 TMM19			0.556	3
UniProt:O95070 YIF1A	1	YIF1A [endoplasmic reticulum membrane] (R-HSA-535599)	0.556	3
UniProt:A0PK00 T120B			0.556	3
UniProt:Q96DZ9-2 CMTM5			0.556	3