Formation of N-glucuronides

Stable Identifier
R-HSA-174916
Type
Reaction [transition]
Species
Homo sapiens
Compartment
ReviewStatus
5/5
Locations in the PathwayBrowser
General
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The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout
Typical N-centred substrates were chosen as examples for these isozymes.
Literature References
PubMed ID Title Journal Year
12433823 Characterization of nicotine and cotinine N-glucuronidations in human liver microsomes

Kwon, JT, Yokoi, T, Nakajima, M, Tanaka, E

Drug Metab Dispos 2002
14570768 N-glucuronidation of nicotine and cotinine by human liver microsomes and heterologously expressed UDP-glucuronosyltransferases

Murphy, SE, Kuehl, GE

Drug Metab Dispos 2003
15135306 Quaternary ammonium-linked glucuronidation of tamoxifen by human liver microsomes and UDP-glucuronosyltransferase 1A4

Ogura, K, Ohnuma, T, Kaku, T, Muro, K, Hiratsuka, A, Nishiyama, T

Biochem Pharmacol 2004
Participants
Participates
Catalyst Activity

glucuronosyltransferase activity of UGT1A3,A4,A9 [endoplasmic reticulum membrane]

Orthologous Events
Reviewed
Created
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