Reactome | MGST3 [endoplasmic reticulum membrane]

MGST3 [endoplasmic reticulum membrane]

Stable Identifier

R-HSA-176053

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

endoplasmic reticulum membrane

Synonyms

Microsomal glutathione S-transferase 3

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:O14880 MGST3

Gene Names

MGST3

Chain

chain:1-152

Reference Genes

BioGPS Gene:4259 MGST3

COSMIC (genes):MGST3 MGST3

CTD Gene:4259 MGST3

dbSNP Gene:4259 MGST3

ENSEMBL:ENSG00000143198 MGST3

ENSEMBL:ENSG00000143198.13 MGST3

HGNC:7064 MGST3

KEGG Gene (Homo sapiens):4259 MGST3

Monarch:4259 MGST3

NCBI Gene:4259 MGST3

OMIM:604564 MGST3

UCSC:O14880 MGST3

Reference Transcript

Other Identifiers

11716165_a_at

11757020_x_at

201403_PM_s_at

201403_s_at

2365124

2365127

2365139

2365142

2365144

2365149

2365151

2365152

2365153

2365154

2365155

2365156

39018_at

4259

7906978

A_23_P51548

A_33_P3316555

GE80860

GO:0003824

GO:0004364

GO:0004464

GO:0004602

GO:0005515

GO:0005634

GO:0005635

GO:0005739

GO:0005741

GO:0005783

GO:0005789

GO:0006629

GO:0006692

GO:0016020

GO:0016209

GO:0016491

GO:0016740

GO:0016829

GO:0019370

GO:0042802

GO:0043226

GO:0043231

GO:0098754

GO:0098869

HMNXSV003007380

ILMN_1751956

PH_hs_0023085

PH_hs_0040343

g4758713_3p_s_at

Participates

as a component of

MGST3 trimer [endoplasmic reticulum membrane] (Homo sapiens)

Inferred To

Mgst3 [endoplasmic reticulum membrane] (Mus musculus)

Mgst3 [endoplasmic reticulum membrane] (Rattus norvegicus)

zgc:56518 [endoplasmic reticulum membrane] (Danio rerio)

cbx8 [endoplasmic reticulum membrane] (Xenopus tropicalis)

MGST3 [endoplasmic reticulum membrane] (Bos taurus)

MGST3 [endoplasmic reticulum membrane] (Canis familiaris)

MGST3 [endoplasmic reticulum membrane] (Gallus gallus)

MGST3 [endoplasmic reticulum membrane] (Sus scrofa)

Cross References

RefSeq

XP_005245231.2, NP_004519.1

OpenTargets

ENSG00000143198

IntEnz

4.4.1.20

GeneCards

O14880

HPA

ENSG00000143198-MGST3

Ensembl

ENST00000367884, ENSP00000356864, ENSP00000356859, ENST00000367889, ENSG00000143198

PRO

O14880

Pharos - Targets

O14880

Orphanet

27476

HMDB Protein

HMDBP00814

Interactors (19)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q00059 TFAM	2	TFAM [mitochondrial matrix] (R-HSA-163312) TFAM(1-246) [cytosol] (R-HSA-1592203)	0.659	4
UniProt:O75396 SEC22B	6	SEC22B [endoplasmic reticulum membrane] (R-HSA-5688150) SEC22B [ER to Golgi transport vesicle membrane] (R-HSA-5688565) SEC22B [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-HSA-5688566) SEC22B [phagocytic vesicle membrane] (R-HSA-8863938) SEC22B [transport vesicle] (R-HSA-6810994) SEC22B [Golgi membrane] (R-HSA-6810993)	0.556	3
UniProt:P78382 SLC35A1	2	SLC35A1 [Golgi membrane] (R-HSA-727812) SLC35A1 V93Cfs*17 [Golgi membrane] (R-HSA-5651957)	0.556	3
UniProt:O00767 SCD	1	SCD [endoplasmic reticulum membrane] (R-HSA-400117)	0.556	3
UniProt:P22732 SLC2A5	2	SLC2A5 [plasma membrane] (R-HSA-189202) SLC2A5 [specific granule membrane] (R-HSA-6799571)	0.556	3
UniProt:Q8N2H4 SYS1	1	SYS1 [trans-Golgi network membrane] (R-HSA-6813921)	0.556	3
UniProt:Q9H2K0 MTIF3	1	MTIF3 [mitochondrial matrix] (R-HSA-5368284)	0.556	3
UniProt:P24863 CCNC	1	CCNC [nucleoplasm] (R-HSA-212418)	0.556	3
UniProt:Q8N661 TMEM86B	1	TMEM86B [endoplasmic reticulum membrane] (R-HSA-8874443)	0.556	3
UniProt:O95070 YIF1A	1	YIF1A [endoplasmic reticulum membrane] (R-HSA-535599)	0.556	3
UniProt:P30825 SLC7A1	1	SLC7A1 [plasma membrane] (R-HSA-375771)	0.556	3
UniProt:Q9Y5Z9 UBIAD1	1	UBIAD1 [endoplasmic reticulum membrane] (R-HSA-2980965)	0.556	3
UniProt:O15155 BET1	3	BET1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-HSA-5688142) BET1 [transport vesicle] (R-HSA-6808719) BET1 [Golgi membrane] (R-HSA-6807743)	0.556	3
UniProt:Q6IN84 MRM1	1	MRM1 [mitochondrial matrix] (R-HSA-6793088)	0.556	3
UniProt:Q15836 VAMP3	6	VAMP3 [recycling endosome membrane] (R-HSA-2029063) VAMP3 [phagocytic vesicle membrane] (R-HSA-2029013) VAMP3 [plasma membrane] (R-HSA-8867599) VAMP3 [trans-Golgi network membrane] (R-HSA-6814624) VAMP3 [transport vesicle] (R-HSA-6814625) VAMP3 [clathrin-coated endocytic vesicle membrane] (R-HSA-8869130)	0.556	3
UniProt:P05090 APOD	1	APOD [extracellular region] (R-HSA-5216199)	0.556	3
UniProt:Q96BA8 CREB3L1	7	CREB3L1 [Golgi membrane] (R-HSA-8874155) CREB3L1(427-519) [Golgi membrane] (R-HSA-8874139) CREB3L1(1-426) [Golgi membrane] (R-HSA-8874153) CREB3L1 [endoplasmic reticulum membrane] (R-HSA-8874157) CREB3L1(1-375) [cytosol] (R-HSA-8874215) CREB3L1(376-426) [Golgi membrane] (R-HSA-8874213) CREB3L1(1-375) [nucleoplasm] (R-HSA-8874222)	0.556	3
UniProt:O75379 VAMP4	4	VAMP4 [transport vesicle] (R-HSA-6811023) VAMP4 [trans-Golgi network membrane] (R-HSA-6811021) VAMP4 [plasma membrane] (R-HSA-8864461) VAMP4 [clathrin-coated endocytic vesicle membrane] (R-HSA-8869133)	0.556	3
UniProt:Q13277 STX3	1	STX3 [plasma membrane] (R-HSA-449131)	0.556	3

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