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Rad17-RFC complex bound to DNA [nucleoplasm]
Stable Identifier
R-HSA-176204
Type
Complex
Species
Homo sapiens
Compartment
nucleoplasm
Locations in the PathwayBrowser
Expand all
Cell Cycle (Homo sapiens)
Cell Cycle Checkpoints (Homo sapiens)
G2/M Checkpoints (Homo sapiens)
Activation of ATR in response to replication stress (Homo sapiens)
Recruitment of Rad17-RFC complex to DNA (Homo sapiens)
Rad17-RFC complex bound to DNA [nucleoplasm] (Homo sapiens)
Recruitment of the Rad9-Hus1-Rad1 complex to DNA (Homo sapiens)
Rad17-RFC complex bound to DNA [nucleoplasm] (Homo sapiens)
Rad9-Hus1-Rad1 bound to DNA [nucleoplasm] (Homo sapiens)
Rad17-RFC complex bound to DNA [nucleoplasm] (Homo sapiens)
General
Rad17-RFC complex associates with DNA substrates containing ssDNA regions including gapped or primed DNA in an ATP-independent reaction. Loading of the Rad9-Hus1-Rad1 (9-1-1) complex occurs preferentially on DNA substrates containing a 5' recessed end. This contrasts with the loading of PCNA by RFC which preferentially occurs on DNA with 3' recessed ends.
Participants
components
RAD17:RFC [nucleoplasm]
(Homo sapiens)
RPA complexed to ssDNA [nucleoplasm]
(Homo sapiens)
Participates
as an output of
Recruitment of Rad17-RFC complex to DNA (Homo sapiens)
as a component of
Rad9-Hus1-Rad1 bound to DNA [nucleoplasm] (Homo sapiens)
as an input of
Recruitment of the Rad9-Hus1-Rad1 complex to DNA (Homo sapiens)
Inferred To
Rad17-RFC complex bound to DNA [nucleoplasm]
(Bos taurus)
Rad17-RFC complex bound to DNA [nucleoplasm]
(Caenorhabditis elegans)
Rad17-RFC complex bound to DNA [nucleoplasm]
(Canis familiaris)
Rad17-RFC complex bound to DNA [nucleoplasm]
(Danio rerio)
Rad17-RFC complex bound to DNA [nucleoplasm]
(Dictyostelium discoideum)
Rad17-RFC complex bound to DNA [nucleoplasm]
(Drosophila melanogaster)
Rad17-RFC complex bound to DNA [nucleoplasm]
(Gallus gallus)
Rad17-RFC complex bound to DNA [nucleoplasm]
(Mus musculus)
Rad17-RFC complex bound to DNA [nucleoplasm]
(Plasmodium falciparum)
Rad17-RFC complex bound to DNA [nucleoplasm]
(Rattus norvegicus)
Rad17-RFC complex bound to DNA [nucleoplasm]
(Saccharomyces cerevisiae)
Rad17-RFC complex bound to DNA [nucleoplasm]
(Schizosaccharomyces pombe)
Rad17-RFC complex bound to DNA [nucleoplasm]
(Sus scrofa)
Rad17-RFC complex bound to DNA [nucleoplasm]
(Xenopus tropicalis)
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