SULTs transfer (SO4)2- group to PREG

Stable Identifier
R-HSA-176517
Type
Reaction [transition]
Species
Homo sapiens
Compartment
cytosol
Synonyms
pregnenolone + PAPS => pregnenolone sulfate + PAP
ReviewStatus
5/5
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SULTs transfer (SO4)2- group to PREG
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The sulfonation of pregnenolone (PREG) is catalyzed by both the a and b isoforms of SULT2B1, although the a isoform is more active in assays in vitro (Fuda et al. 2002; Meloche and Falany 2001).
Literature References
Participants
Input
Output
Participates
as an event of
Catalyst Activity

steroid sulfotransferase activity of SULTs active on pregnenolone [cytosol]

Physical Entity
SULTs active on pregnenolone [cytosol] (Homo sapiens)
Activity
steroid sulfotransferase activity (GO:0050294)
Orthologous Events
SULTs transfer (SO4)2- group to PREG (Bos taurus)
SULTs transfer (SO4)2- group to PREG (Canis familiaris)
SULTs transfer (SO4)2- group to PREG (Danio rerio)
SULTs transfer (SO4)2- group to PREG (Drosophila melanogaster)
SULTs transfer (SO4)2- group to PREG (Gallus gallus)
SULTs transfer (SO4)2- group to PREG (Mus musculus)
SULTs transfer (SO4)2- group to PREG (Rattus norvegicus)
SULTs transfer (SO4)2- group to PREG (Sus scrofa)
SULTs transfer (SO4)2- group to PREG (Xenopus tropicalis)
Cross References
Rhea
Reviewed
D'Eustachio, P  (2008-05-28)
Created
D'Eustachio, P  (2006-03-09)
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