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SULT2A1 [cytosol]
Stable Identifier
R-HSA-176559
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Locations in the PathwayBrowser
Expand all
Drug ADME (Homo sapiens)
Paracetamol ADME (Homo sapiens)
SULT dimers sulfate APAP to APAP-SO3 (Homo sapiens)
SULT dimers (APAP) [cytosol] (Homo sapiens)
SULT2A1 dimer [cytosol] (Homo sapiens)
SULT2A1 [cytosol] (Homo sapiens)
Metabolism (Homo sapiens)
Biological oxidations (Homo sapiens)
Phase II - Conjugation of compounds (Homo sapiens)
Cytosolic sulfonation of small molecules (Homo sapiens)
3,3'-diiodothyronine + PAPS => 3,3'-diiodothyronine 4-sulfate + PAP (Homo sapiens)
SULT dimers (T2) [cytosol] (Homo sapiens)
SULT2A1 dimer [cytosol] (Homo sapiens)
SULT2A1 [cytosol] (Homo sapiens)
3,5,3'-triiodothyronine + PAPS => 3,5,3'-triiodothyronine 4-sulfate + PAP (Homo sapiens)
SULT dimers (T3) [cytosol] (Homo sapiens)
SULT2A1 dimer [cytosol] (Homo sapiens)
SULT2A1 [cytosol] (Homo sapiens)
dehydroepiandrosterone (DHEA) + PAPS => DHEA sulfate + PAP (Homo sapiens)
SULTs active on DHEA [cytosol] (Homo sapiens)
SULT2A1 dimer [cytosol] (Homo sapiens)
SULT2A1 [cytosol] (Homo sapiens)
estrone + PAPS => estrone 3-sulfate + PAP (Homo sapiens)
SULT1E1,2A1 [cytosol] (Homo sapiens)
SULT2A1 dimer [cytosol] (Homo sapiens)
SULT2A1 [cytosol] (Homo sapiens)
lithocholate + PAPS => lithocholate sulfate + PAP (Homo sapiens)
SULT2A1 dimer [cytosol] (Homo sapiens)
SULT2A1 [cytosol] (Homo sapiens)
taurolithocholate + PAPS => taurolithocholate sulfate + PAP (Homo sapiens)
SULT2A1 dimer [cytosol] (Homo sapiens)
SULT2A1 [cytosol] (Homo sapiens)
Metabolism of lipids (Homo sapiens)
Regulation of lipid metabolism by PPARalpha (Homo sapiens)
PPARA activates gene expression (Homo sapiens)
Expression of SULT2A1 (Homo sapiens)
SULT2A1 [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q06520 SULT2A1
Gene Names
SULT2A1, HST, STD
Chain
chain:1-285
Reference Genes
BioGPS Gene:6822 SULT2A1
COSMIC (genes):SULT2A1 SULT2A1
CTD Gene:6822 SULT2A1
dbSNP Gene:6822 SULT2A1
ENSEMBL:ENSG00000105398 SULT2A1
ENSEMBL_homo_sapiens_GENE:ENSG00000105398.4 SULT2A1
HGNC:11458 SULT2A1
KEGG Gene (Homo sapiens):6822 SULT2A1
Monarch:6822 SULT2A1
NCBI Gene:6822 SULT2A1
OMIM:125263 SULT2A1
UCSC:Q06520 SULT2A1
Reference Transcript
RefSeq:NM_003167.3 SULT2A1
Other Identifiers
11730276_at
11730277_at
16873800
206292_PM_s_at
206292_s_at
206293_PM_at
206293_at
3866786
3866787
3866788
3866790
3866792
3866793
3866794
3866795
3866796
3866797
3866798
523_s_at
6822
8037949
85557_r_at
A_23_P67381
A_24_P224684
GE60527
GO:0003824
GO:0004027
GO:0005515
GO:0005737
GO:0005829
GO:0006068
GO:0006575
GO:0006629
GO:0006790
GO:0006805
GO:0008146
GO:0008202
GO:0008203
GO:0016042
GO:0016740
GO:0030573
GO:0042403
GO:0047704
GO:0050294
GO:0050427
GO:0050656
GO:0051923
GO:0055086
GO:1901135
HMNXSV003045629
ILMN_1692983
PH_hs_0031362
TC19001670.hg
U13061_rna1_at
g4507306_3p_a_at
g468250_3p_at
Participates
as an output of
Expression of SULT2A1 (Homo sapiens)
as a component of
SULT2A1 dimer [cytosol] (Homo sapiens)
Inferred To
SULT2A1 [cytosol]
(Bos taurus)
SULT2A1 [cytosol]
(Gallus gallus)
SULT2A1 [cytosol]
(Mus musculus)
SULT2A1 [cytosol]
(Rattus norvegicus)
SULT2A1 [cytosol]
(Sus scrofa)
sult2a1 [cytosol]
(Xenopus tropicalis)
St1 [cytosol]
(Drosophila melanogaster)
St4 [cytosol]
(Drosophila melanogaster)
sult2st2 [cytosol]
(Danio rerio)
XB5850668 [cytosol]
(Xenopus tropicalis)
St2 [cytosol]
(Drosophila melanogaster)
sult2st3 [cytosol]
(Danio rerio)
Homologues of SULT2A1 [cytosol]
(Danio rerio)
Homologues of SULT2A1 [cytosol]
(Drosophila melanogaster)
Homologues of SULT2A1 [cytosol]
(Gallus gallus)
Homologues of SULT2A1 [cytosol]
(Mus musculus)
Homologues of SULT2A1 [cytosol]
(Rattus norvegicus)
Homologues of SULT2A1 [cytosol]
(Xenopus tropicalis)
St3 [cytosol]
(Drosophila melanogaster)
sult2st1 [cytosol]
(Danio rerio)
Cross References
RefSeq
NP_003158.2
OpenTargets
ENSG00000105398
IntEnz
2.8.2.14
HPA
ENSG00000105398-SULT2A1
GeneCards
Q06520
Ensembl
ENST00000222002
,
ENSG00000105398
,
ENSP00000222002
PRO
Q06520
Pharos - Targets
Q06520
HMDB Protein
HMDBP00347
PDB
2QP3
,
2QP4
,
1J99
,
4IFB
,
1OV4
,
3F3Y
,
1EFH
Interactors (3)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:O43704 SULT1B1
1
SULT1B1 [cytosol]
(R-HSA-176551)
0.718
6
UniProt:Q9GZT8 NIF3L
0.556
3
UniProt:P40763 STAT3
12
Unfolded STAT3 [cytosol]
(R-HSA-6813811)
p-STAT3 [nucleoplasm]
(R-HSA-8983188)
p-STAT3 [cytosol]
(R-HSA-8982823)
AcK685- p-Y705,S727-STAT3 [nucleoplasm]
(R-HSA-9701435)
p-Y705,S727-STAT3 [nucleoplasm]
(R-HSA-9701429)
p-S727-STAT3 [cytosol]
(R-HSA-198705)
p-Y705,S727-STAT3 [cytosol]
(R-HSA-539048)
p-Y705-STAT3 [nucleoplasm]
(R-HSA-9027589)
p-Y705-STAT3 [cytosol]
(R-HSA-8983130)
STAT3 [cytosol]
(R-HSA-539044)
p-Y705-STAT3 [cytosol]
(R-HSA-914048)
p-Y705-STAT3 [nucleoplasm]
(R-HSA-1112554)
0.508
2
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