taurolithocholate + PAPS => taurolithocholate sulfate + PAP

Stable Identifier
R-HSA-176604
Type
Reaction [transition]
Species
Homo sapiens
Compartment
cytosol
ReviewStatus
5/5
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taurolithocholate + PAPS => taurolithocholate sulfate + PAP
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The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout
Sulfonation of taurolithocholate is catalyzed by SULT2A1 (Radominska et al. 1990).
Literature References
PubMed ID Title Journal Year
2268288 Human liver steroid sulphotransferase sulphates bile acids

Iscan, M, Falany, JL, Zimniak, P, Comer, KA, Radominska, A, Falany, CN

Biochem J 1990
Participants
Input
Output
Participates
as an event of
Catalyst Activity

sulfotransferase activity of SULT2A1 dimer [cytosol]

Physical Entity
SULT2A1 dimer [cytosol] (Homo sapiens)
Activity
sulfotransferase activity (GO:0008146)
Orthologous Events
taurolithocholate + PAPS => taurolithocholate sulfate + PAP (Bos taurus)
taurolithocholate + PAPS => taurolithocholate sulfate + PAP (Danio rerio)
taurolithocholate + PAPS => taurolithocholate sulfate + PAP (Drosophila melanogaster)
taurolithocholate + PAPS => taurolithocholate sulfate + PAP (Gallus gallus)
taurolithocholate + PAPS => taurolithocholate sulfate + PAP (Mus musculus)
taurolithocholate + PAPS => taurolithocholate sulfate + PAP (Rattus norvegicus)
taurolithocholate + PAPS => taurolithocholate sulfate + PAP (Sus scrofa)
taurolithocholate + PAPS => taurolithocholate sulfate + PAP (Xenopus tropicalis)
Cross References
Rhea
Reviewed
D'Eustachio, P  (2008-05-28)
Created
D'Eustachio, P  (2006-03-09)
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