Reactome | dehydroepiandrosterone (DHEA) + PAPS => DHEA sulfate + PAP

dehydroepiandrosterone (DHEA) + PAPS => DHEA sulfate + PAP

Stable Identifier

R-HSA-176631

Type

Reaction [transition]

Species

Homo sapiens

Compartment

cytosol

ReviewStatus

5/5

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dehydroepiandrosterone (DHEA) + PAPS => DHEA sulfate + PAP

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Sulfonation of dehydroepiandrosterone (DHEA) is catalyzed by SULT1E1 (Aksoy et al. 1994), SULT2A1 (Radominska et al. 1990) and the a and b isoforms of SULT2B1 (Meloche and Falany 2001).

Literature References

PubMed ID	Title	Journal	Year
8185618	Human liver estrogen sulfotransferase: identification by cDNA cloning and expression Weinshilboum, RM, Wood, TC, Aksoy, IA	Biochem Biophys Res Commun	1994
2268288	Human liver steroid sulphotransferase sulphates bile acids Iscan, M, Falany, JL, Zimniak, P, Comer, KA, Radominska, A, Falany, CN	Biochem J	1990
11457664	Expression and characterization of the human 3 beta-hydroxysteroid sulfotransferases (SULT2B1a and SULT2B1b) Meloche, CA, Falany, CN	J Steroid Biochem Mol Biol	2001