Reactome | p-nitrophenol + PAPS => p-nitrophenol sulfate + PAP

p-nitrophenol + PAPS => p-nitrophenol sulfate + PAP

Stable Identifier

R-HSA-176646

Type

Reaction [transition]

Species

Homo sapiens

Compartment

cytosol

ReviewStatus

5/5

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p-nitrophenol + PAPS => p-nitrophenol sulfate + PAP

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The sulfonation of the xenobiotic p-nitrophenol (4-nitrophenol) can be catalyzed by five well-characterized SULT enzymes, 1A1 (Brix et al. 1998), 1A2 (Brix et al. 1998; Zhu et al. 1996), 1C2 (Sakakibara et al. 1998), and 4A1 (Sakakibara et al. 2002).

Literature References

PubMed ID	Title	Journal	Year
9852044	Molecular cloning, expression, and characterization of novel human SULT1C sulfotransferases that catalyze the sulfonation of N-hydroxy-2-acetylaminofluorene Sakakibara, Y, Yanagisawa, K, Katafuchi, J, Ringer, DP, Takami, Y, Nakayama, T, Suiko, M, Liu, MC	J Biol Chem	1998
9566739	Structural and functional characterisation of human sulfotransferases Brix, LA, Nicoll, R, Zhu, X, McManus, ME	Chem Biol Interact	1998
12039030	Highly conserved mouse and human brain sulfotransferases: molecular cloning, expression, and functional characterization Sakakibara, Y, Suiko, M, Pai, TG, Nakayama, T, Takami, Y, Katafuchi, J, Liu, MC	Gene	2002
8697101	cDNA cloning and expression of a new form of human aryl sulfotransferase Zhu, X, Veronese, ME, Iocco, P, McManus, ME	Int J Biochem Cell Biol	1996