Reactome | p-nitrophenol + PAPS => p-nitrophenol sulfate + PAP

p-nitrophenol + PAPS => p-nitrophenol sulfate + PAP

Stable Identifier

R-HSA-176646

Type

Reaction [transition]

Species

Homo sapiens

Compartment

cytosol

ReviewStatus

5/5

Locations in the PathwayBrowser

Expand all

General

SBML | | PDF

SVG | | PPTX | SBGN

p-nitrophenol + PAPS => p-nitrophenol sulfate + PAP

Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout

The sulfonation of the xenobiotic p-nitrophenol (4-nitrophenol) can be catalyzed by five well-characterized SULT enzymes, 1A1 (Brix et al. 1998), 1A2 (Brix et al. 1998; Zhu et al. 1996), 1C2 (Sakakibara et al. 1998), and 4A1 (Sakakibara et al. 2002).

Literature References

PubMed ID	Title	Journal	Year
9852044	Molecular cloning, expression, and characterization of novel human SULT1C sulfotransferases that catalyze the sulfonation of N-hydroxy-2-acetylaminofluorene Liu, MC, Nakayama, T, Ringer, DP, Suiko, M, Takami, Y, Sakakibara, Y, Katafuchi, J, Yanagisawa, K	J Biol Chem	1998
9566739	Structural and functional characterisation of human sulfotransferases Nicoll, R, McManus, ME, Brix, LA, Zhu, X	Chem Biol Interact	1998
12039030	Highly conserved mouse and human brain sulfotransferases: molecular cloning, expression, and functional characterization Liu, MC, Nakayama, T, Pai, TG, Suiko, M, Takami, Y, Sakakibara, Y, Katafuchi, J	Gene	2002
8697101	cDNA cloning and expression of a new form of human aryl sulfotransferase Iocco, P, McManus, ME, Veronese, ME, Zhu, X	Int J Biochem Cell Biol	1996