p-nitrophenol + PAPS => p-nitrophenol sulfate + PAP

Stable Identifier
R-HSA-176646
Type
Reaction [transition]
Species
Homo sapiens
Compartment
ReviewStatus
5/5
Locations in the PathwayBrowser
General
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The sulfonation of the xenobiotic p-nitrophenol (4-nitrophenol) can be catalyzed by five well-characterized SULT enzymes, 1A1 (Brix et al. 1998), 1A2 (Brix et al. 1998; Zhu et al. 1996), 1C2 (Sakakibara et al. 1998), and 4A1 (Sakakibara et al. 2002).
Literature References
PubMed ID Title Journal Year
9852044 Molecular cloning, expression, and characterization of novel human SULT1C sulfotransferases that catalyze the sulfonation of N-hydroxy-2-acetylaminofluorene

Liu, MC, Nakayama, T, Ringer, DP, Suiko, M, Takami, Y, Sakakibara, Y, Katafuchi, J, Yanagisawa, K

J Biol Chem 1998
9566739 Structural and functional characterisation of human sulfotransferases

Nicoll, R, McManus, ME, Brix, LA, Zhu, X

Chem Biol Interact 1998
12039030 Highly conserved mouse and human brain sulfotransferases: molecular cloning, expression, and functional characterization

Liu, MC, Nakayama, T, Pai, TG, Suiko, M, Takami, Y, Sakakibara, Y, Katafuchi, J

Gene 2002
8697101 cDNA cloning and expression of a new form of human aryl sulfotransferase

Iocco, P, McManus, ME, Veronese, ME, Zhu, X

Int J Biochem Cell Biol 1996
Participants
Participates
Catalyst Activity

aryl sulfotransferase activity of SULT1A1,A2,C2,4A1 [cytosol]

Orthologous Events
Cross References
Rhea
Reviewed
Created
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