Reactome | estrone + PAPS => estrone 3-sulfate + PAP

estrone + PAPS => estrone 3-sulfate + PAP

Stable Identifier

R-HSA-176664

Type

Reaction [transition]

Species

Homo sapiens

Compartment

cytosol

ReviewStatus

5/5

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estrone + PAPS => estrone 3-sulfate + PAP

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Sulfonation of estrone is catalyzed by SULT1E1 (Aksoy et al. 1994; Falany et al. 1995), and also by SULT2A1 (Comer et al. 1993), although the efficiency of SULT2A1 catalysis is unknown.

Literature References

PubMed ID	Title	Journal	Year
7678732	Cloning and expression of human liver dehydroepiandrosterone sulphotransferase Comer, KA, Falany, JL, Falany, CN	Biochem J	1993
8185618	Human liver estrogen sulfotransferase: identification by cDNA cloning and expression Aksoy, IA, Weinshilboum, RM, Wood, TC	Biochem Biophys Res Commun	1994
7779757	Bacterial expression and characterization of a cDNA for human liver estrogen sulfotransferase Falany, CN, Krasnykh, V, Falany, JL	J Steroid Biochem Mol Biol	1995