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GINS1 [nucleoplasm]
Stable Identifier
R-HSA-176955
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
PSF1p
Locations in the PathwayBrowser
Expand all
Cell Cycle (Homo sapiens)
Cell Cycle, Mitotic (Homo sapiens)
S Phase (Homo sapiens)
Synthesis of DNA (Homo sapiens)
DNA strand elongation (Homo sapiens)
Unwinding of DNA (Homo sapiens)
Formation of GINS complex (Homo sapiens)
GINS complex [nucleoplasm] (Homo sapiens)
GINS1 [nucleoplasm] (Homo sapiens)
GINS1 [nucleoplasm] (Homo sapiens)
Multiple proteins are localized at replication fork (Homo sapiens)
GINS complex [nucleoplasm] (Homo sapiens)
GINS1 [nucleoplasm] (Homo sapiens)
Unwinding complex at replication fork [nucleoplasm] (Homo sapiens)
GINS complex [nucleoplasm] (Homo sapiens)
GINS1 [nucleoplasm] (Homo sapiens)
DNA Replication (Homo sapiens)
Synthesis of DNA (Homo sapiens)
DNA strand elongation (Homo sapiens)
Unwinding of DNA (Homo sapiens)
Formation of GINS complex (Homo sapiens)
GINS complex [nucleoplasm] (Homo sapiens)
GINS1 [nucleoplasm] (Homo sapiens)
GINS1 [nucleoplasm] (Homo sapiens)
Multiple proteins are localized at replication fork (Homo sapiens)
GINS complex [nucleoplasm] (Homo sapiens)
GINS1 [nucleoplasm] (Homo sapiens)
Unwinding complex at replication fork [nucleoplasm] (Homo sapiens)
GINS complex [nucleoplasm] (Homo sapiens)
GINS1 [nucleoplasm] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q14691 GINS1
Gene Names
GINS1, KIAA0186, PSF1
Chain
chain:1-196
Reference Genes
BioGPS Gene:9837 GINS1
COSMIC (genes):GINS1 GINS1
CTD Gene:9837 GINS1
dbSNP Gene:9837 GINS1
ENSEMBL:ENSG00000101003 GINS1
ENSEMBL_homo_sapiens_GENE:ENSG00000101003.12 GINS1
HGNC:28980 GINS1
KEGG Gene (Homo sapiens):9837 GINS1
Monarch:9837 GINS1
NCBI Gene:9837 GINS1
OMIM:610608 GINS1
UCSC:Q14691 GINS1
Reference Transcript
RefSeq:NM_021067.4 GINS1
Other Identifiers
11728863_at
11728864_at
11749970_a_at
16912192
206102_PM_at
206102_at
3880828
3880829
3880833
3880834
3880836
3880839
3880842
3880844
3880845
3880846
39677_at
8061471
9837
A_14_P104044
A_14_P134876
A_33_P3340025
D80008_at
GE61202
GO:0000228
GO:0000278
GO:0000811
GO:0001833
GO:0005515
GO:0005634
GO:0005654
GO:0005694
GO:0005737
GO:0006260
GO:0006268
GO:0043226
GO:0048856
GO:0071162
GO:1902983
HMNXSV003030589
HMNXSV003036249
ILMN_1697751
PH_hs_0024018
TC20000169.hg
g10800147_3p_at
Participates
as a component of
GINS complex [nucleoplasm] (Homo sapiens)
as an input of
Formation of GINS complex (Homo sapiens)
Inferred To
PSF1 [nucleoplasm]
(Saccharomyces cerevisiae)
psf-1 [nucleoplasm]
(Caenorhabditis elegans)
zgc:101672 [nucleoplasm]
(Danio rerio)
GINS1 [nucleoplasm]
(Bos taurus)
GINS1 [nucleoplasm]
(Canis familiaris)
GINS1 [nucleoplasm]
(Gallus gallus)
GINS1 [nucleoplasm]
(Rattus norvegicus)
GINS1 [nucleoplasm]
(Sus scrofa)
gins1 [nucleoplasm]
(Dictyostelium discoideum)
gins1 [nucleoplasm]
(Xenopus tropicalis)
psf1 [nucleoplasm]
(Schizosaccharomyces pombe)
Psf1 [nucleoplasm]
(Drosophila melanogaster)
Gins1 [nucleoplasm]
(Mus musculus)
Cross References
RefSeq
NP_066545.3
OpenTargets
ENSG00000101003
HPA
ENSG00000101003-GINS1
GeneCards
Q14691
Ensembl
ENST00000696874
,
ENST00000262460
,
ENSP00000512943
,
ENSG00000101003
,
ENSP00000262460
PRO
Q14691
Pharos - Targets
Q14691
Orphanet
24561
PDB
2Q9Q
,
2EHO
,
2E9X
,
7PFO
,
6XTY
,
6XTX
,
8B9D
,
7PLO
Interactors (5)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q9BRX5 GINS3
1
GINS3 [nucleoplasm]
(R-HSA-5688046)
0.801
7
UniProt:Q9BRT9 GINS4
1
GINS4 [nucleoplasm]
(R-HSA-176963)
0.743
6
UniProt:Q9Y248 GINS2
1
GINS2 [nucleoplasm]
(R-HSA-176975)
0.743
6
UniProt:Q9NYP3 DONS
0.584
7
UniProt:O75419 CDC45
1
CDC45 [nucleoplasm]
(R-HSA-68563)
0.499
3
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