Multi-ubiquitination of APOBEC3G

Stable Identifier
R-HSA-180540
Type
Reaction [transition]
Species
Homo sapiens
Related Species
Human immunodeficiency virus 1
Compartment
cytosol
ReviewStatus
5/5
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Multi-ubiquitination of APOBEC3G
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APOBEC3G is multi-ubiquitinated by the Vif-Cul5-SCF complex.

Literature References
PubMed ID Title Journal Year
15781449 Ubiquitination of APOBEC3G by an HIV-1 Vif-Cullin5-Elongin B-Elongin C complex is essential for Vif function

Uchiyama, T, Takaori-Kondo, A, Miyauchi, Y, Iwai, K, Kobayashi, M

J Biol Chem 2005
Participants
Input
Output
Participates
as an event of
Catalyst Activity

ubiquitin-protein transferase activity of APOBEC3G:Vif:Cul5:SCF complex [cytosol]

Physical Entity
APOBEC3G:Vif:Cul5:SCF complex [cytosol] (Homo sapiens)
Activity
ubiquitin-protein transferase activity (GO:0004842)
Disease
Name Identifier Synonyms
Human immunodeficiency virus infectious disease DOID:526 HIV infection
Authored
Matthews, L  (2006-05-16)
Reviewed
Mulder, L  (2007-01-31)
Simon, V  (2007-01-31)
Created
Matthews, L  (2006-05-23)
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