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FIG4 [early endosome membrane]
Stable Identifier
R-HSA-1806255
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
early endosome membrane
Synonyms
Polyphosphoinositide phosphatase, FIG4_HUMAN, SAC3
Locations in the PathwayBrowser
Expand all
Metabolism (Homo sapiens)
Metabolism of lipids (Homo sapiens)
Phospholipid metabolism (Homo sapiens)
PI Metabolism (Homo sapiens)
Synthesis of PIPs at the early endosome membrane (Homo sapiens)
PI(3,5)P2 is dephosphorylated to PI3P by FIG4 at the early endosome membrane (Homo sapiens)
FIG4 [early endosome membrane] (Homo sapiens)
PIKFYVE:VAC14:FIG4 [early endosome membrane] (Homo sapiens)
FIG4 [early endosome membrane] (Homo sapiens)
PI3P is phosphorylated to PI(3,5)P2 by PIKFYVE at the early endosome membrane (Homo sapiens)
PIKFYVE:VAC14:FIG4 [early endosome membrane] (Homo sapiens)
FIG4 [early endosome membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q92562 FIG4
Gene Names
FIG4, KIAA0274, SAC3
Chain
chain:1-907
Reference Genes
BioGPS Gene:9896 FIG4
COSMIC (genes):FIG4 FIG4
CTD Gene:9896 FIG4
dbSNP Gene:9896 FIG4
ENSEMBL:ENSG00000112367 FIG4
ENSEMBL_homo_sapiens_GENE:ENSG00000112367.12 FIG4
HGNC:16873 FIG4
KEGG Gene (Homo sapiens):9896 FIG4
Monarch:9896 FIG4
NCBI Gene:9896 FIG4
OMIM:609390 FIG4
UCSC:Q92562 FIG4
Reference Transcript
RefSeq:NM_014845.5 FIG4
Other Identifiers
11715265_at
17011593
203656_PM_at
203656_at
2920963
2920964
2920967
2920968
2920969
2920970
2920971
2920973
2920974
2920976
2920979
2920980
2920983
2920985
2920987
2920989
2920990
2920991
2920994
2920996
2921000
2921001
2921003
2921005
2921007
2921015
2921016
41101_at
8121429
9896
A_14_P119840
A_14_P124494
A_23_P145541
A_33_P3337981
D87464_at
GE62789
GO:0000139
GO:0003824
GO:0004439
GO:0004722
GO:0005515
GO:0005768
GO:0005794
GO:0005811
GO:0006629
GO:0006661
GO:0007033
GO:0007626
GO:0010008
GO:0016020
GO:0016787
GO:0016791
GO:0030154
GO:0031410
GO:0031642
GO:0031901
GO:0031902
GO:0032288
GO:0034485
GO:0036092
GO:0042552
GO:0043226
GO:0043231
GO:0043473
GO:0043813
GO:0046488
GO:0046856
GO:0048666
GO:0048856
GO:0050877
GO:0140096
HMNXSV003032646
ILMN_1800889
TC06000879.hg
g7662033_3p_at
Participates
as a component of
Pikfyve:VAC14:FIG4 [early endosome membrane] (Mus musculus)
PIKFYVE:VAC14:FIG4 [early endosome membrane] (Homo sapiens)
Other forms of this molecule
FIG4 [late endosome membrane]
FIG4 [Golgi membrane]
Inferred To
Fig4 [early endosome membrane]
(Mus musculus)
FIG4 [early endosome membrane]
(Bos taurus)
FIG4 [early endosome membrane]
(Canis familiaris)
FIG4 [early endosome membrane]
(Gallus gallus)
FIG4 [early endosome membrane]
(Rattus norvegicus)
FIG4 [early endosome membrane]
(Sus scrofa)
Cross References
RefSeq
NP_055660.1
OpenTargets
ENSG00000112367
IntEnz
3.1.3.86
,
3.1.3.36
,
3.1.3.16
GeneCards
Q92562
HPA
ENSG00000112367-FIG4
Ensembl
ENSP00000230124
,
ENSG00000112367
,
ENST00000230124
PRO
Q92562
Pharos - Targets
Q92562
Orphanet
17288
PDB
7K1W
HMDB Protein
HMDBP14048
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