Reactome | RCC1 [nucleoplasm]

RCC1 [nucleoplasm]

Stable Identifier

R-HSA-180690

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

Rcc1

Locations in the PathwayBrowser for interactor GDP [ChEBI:17552]

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External Reference Information

External Reference

UniProt:P18754 RCC1

Gene Names

RCC1, CHC1

Chain

initiator methionine:1, chain:2-421

Reference Genes

BioGPS Gene:1104 RCC1

COSMIC (genes):RCC1 RCC1

CTD Gene:1104 RCC1

dbSNP Gene:1104 RCC1

ENSEMBL:ENSG00000180198 RCC1

HGNC:1913 RCC1

KEGG:hsa:1104 RCC1

Monarch:1104 RCC1

NCBI Gene:1104 RCC1

OMIM:179710 RCC1

UCSC:P18754 RCC1

Reference Transcript

Other Identifiers

1104

11739421_a_at

11741252_a_at

1196_at

16661589

206499_PM_s_at

206499_s_at

215747_PM_s_at

215747_s_at

2327483

2327487

2327491

2327498

2327500

2327501

2327503

2327504

2327505

2327506

2327507

2327508

2327509

2327510

2327511

2327512

2327513

2327514

2327515

2327516

2327517

2327518

2327519

2327520

2327521

2327522

2327533

2327539

2327540

2327541

3267024

37927_at

7899462

A_14_P120765

A_23_P46309

A_24_P930442

D00591_at

GE59704

GO:0000082

GO:0000228

GO:0000785

GO:0000794

GO:0003677

GO:0003682

GO:0005085

GO:0005515

GO:0005634

GO:0005654

GO:0005694

GO:0005737

GO:0007010

GO:0007052

GO:0007059

GO:0007084

GO:0007088

GO:0007346

GO:0016032

GO:0031267

GO:0031491

GO:0031492

GO:0032991

GO:0042393

GO:0043199

GO:0046982

GO:0051225

GO:0051301

GO:0061024

GO:1901673

HMNXSV003030318

Hs.84746.2.S1_3p_a_at

ILMN_1707493

ILMN_2311497

ILMN_2354211

PH_hs_0030839

PH_hs_0032120

TC01000381.hg

TC01004267.hg

g4502800_3p_a_at

Other forms of this molecule

RCC1 [chromosome]

Cross References

RefSeq

NP_001041664.1, NP_001041660.1, NP_001260.1, NP_001041659.1, NP_001368794.1, NP_001368795.1

OpenTargets

ENSG00000180198

ENSEMBL

ENST00000649185, ENSG00000180198, ENSP00000362939, ENST00000683442, ENSP00000497402, ENST00000373833, ENST00000373832, ENSP00000362938, ENSP00000362937, ENST00000373831, ENST00000398958, ENSP00000381931, ENSP00000508074

HPA

ENSG00000180198-RCC1

GeneCards

RCC1

PRO

P18754

Pharos - Targets

P18754

GlyGen

P18754

HMDB Protein

HMDBP08535

PDB

5E1D, 1A12, 5TBK, 8UX1, 5E2B, 5E1B, 5E1O, 1I2M, 6DUB, 5E1M, 5E2A

Interactors (14)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P62826 RAN	2	RAN [nucleoplasm] (R-HSA-165528) RAN [cytosol] (R-HSA-165540)	0.946	19
UniProt:Q14974 KPNB1	5	KPNB1 [cytosol] (R-HSA-180733) KPNB1 [nucleoplasm] (R-HSA-180714) KPNB1 [specific granule lumen] (R-HSA-6799646) KPNB1 [extracellular region] (R-HSA-6806306) KPNB1 [ficolin-1-rich granule lumen] (R-HSA-6800978)	0.643	3
GDP [ChEBI:17552]	7	GDP [lysosomal membrane] (R-ALL-9628545) GDP [cytoplasmic vesicle membrane] (R-ALL-1996292) GDP [cilium] (R-ALL-5617810) GDP [platelet dense granule lumen] (R-ALL-114622) GDP [nucleoplasm] (R-ALL-111349) GDP [endoplasmic reticulum lumen] (R-ALL-1467290) GDP [plasma membrane] (R-ALL-114549)	0.623	2
UniProt:O14980 XPO1	2	XPO1 [cytosol] (R-HSA-165539) XPO1 [nucleoplasm] (R-HSA-165529)	0.564	2
UniProt:Q9ERU9 Ranbp2	5	Ranbp2 [nuclear envelope] (R-MMU-4551720) Ranbp2 [nuclear envelope] (R-MMU-4551599) Ranbp2 [nuclear envelope] (R-MMU-5228524) Ranbp2 [nuclear envelope] (R-MMU-2993756) Ranbp2 [cytosol] (R-MMU-157703)	0.564	2
UniProt:Q9BV86 NTM1A			0.558	4
UniProt:P63279 UBE2I	9	monoSUMO1-K14-UBE2I [nucleoplasm] (R-HSA-4085358) UBE2I [nuclear envelope] (R-HSA-4655408) SUMO3-C93-UBE2I [nucleoplasm] (R-HSA-3730629) UBE2I [nucleoplasm] (R-HSA-912481) SUMO1-C93-UBE2I [nucleoplasm] (R-HSA-3730617) SUMO2-C93-UBE2I [nucleoplasm] (R-HSA-3730619) SUMO1-C93-UBE2I [cytosol] (R-HSA-4656909) UBE2I [cytosol] (R-HSA-4655342) SUMO2-C93-UBE2I [cytosol] (R-HSA-4656944)	0.527	3
UniProt:P19320 VCAM1	1	VCAM1 [plasma membrane] (R-HSA-197834)	0.527	4
UniProt:P61769 B2M	11	B2M(21-119) [plasma membrane] (R-HSA-167743) B2M(21-119) [endoplasmic reticulum lumen] (R-HSA-983063) B2M(21-119) [tertiary granule lumen] (R-HSA-6800179) B2M(21-119) [extracellular region] (R-HSA-1302721) B2M(21-119) [specific granule lumen] (R-HSA-6806144) B2M(21-119) [Golgi membrane] (R-HSA-983403) B2M(21-119) [ER to Golgi transport vesicle membrane] (R-HSA-983378) B2M(21-119) [early endosome lumen] (R-HSA-1236827) B2M(21-119) [recycling endosome membrane] (R-HSA-8863880) B2M(21-119) [phagocytic vesicle membrane] (R-HSA-1236891) B2M(21-119) [early endosome membrane] (R-HSA-182298)	0.527	4
UniProt:P43487 RANBP1	1	RANBP1 [nuclear envelope] (R-HSA-167651)	0.527	3
UniProt:O00629 KPNA4	2	KPNA4 [cytosol] (R-HSA-1176066) KPNA4 [nucleoplasm] (R-HSA-1176058)	0.527	3
UniProt:Q9H6Z4 RANB3			0.508	2
UniProt:P02281 H2B11			0.499	2
UniProt:P48729 CSNK1A1	3	CSNK1A1 [nucleoplasm] (R-HSA-9943726) CSNK1A1 [cytosol] (R-HSA-195263) CSNK1A1 [cilium] (R-HSA-5632507)	0.488	3

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