Translocation of Rev:importin-beta:B23 to the nucleus

Stable Identifier
R-HSA-180732
Type
Reaction [dissociation]
Species
Homo sapiens
Related Species
Human immunodeficiency virus 1
Compartment
nucleoplasm, nuclear envelope
ReviewStatus
5/5
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Translocation of Rev:importin-beta:B23 to the nucleus
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The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout
Following the association of Rev with importin-beta, the Rev:B23:importin-beta complex is imported into the nucleus.
Literature References
PubMed ID Title Journal Year
9092824 Nucleolar protein B23 stimulates nuclear import of the HIV-1 Rev protein and NLS-conjugated albumin

Mehrotra, B, Wingfield, PT, Baumann, A, Szebeni, A, Olson, MO, Adam, SA

Biochemistry 1997
Participants
Input
Output
Participates
as an event of
Inferred From
Disassembly of the Rev-importin beta-B23:Ran-GTP complex (Homo sapiens)
Orthologous Events
Rev:importin beta:B23 recruited to the nuclear pore (Homo sapiens)
Disease
Name Identifier Synonyms
Human immunodeficiency virus infectious disease DOID:526 HIV infection
Authored
Matthews, L  (2006-06-08)
Reviewed
Kumar, A  (2007-02-01)
Created
Matthews, L  (2006-06-02)
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