Reactome | CDKN2B [cytosol]

CDKN2B [cytosol]

Stable Identifier

R-HSA-182586

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

P15-INK4B, Cyclin-dependent kinase 4 inhibitor B, MTS2

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:P42772 CDKN2B

Gene Names

CDKN2B, MTS2

Chain

chain:1-138

Reference Genes

BioGPS Gene:1030 CDKN2B

COSMIC (genes):CDKN2B CDKN2B

CTD Gene:1030 CDKN2B

dbSNP Gene:1030 CDKN2B

ENSEMBL:ENSG00000147883 CDKN2B

HGNC:1788 CDKN2B

KEGG:hsa:1030 CDKN2B

Monarch:1030 CDKN2B

NCBI Gene:1030 CDKN2B

OMIM:600431 CDKN2B

UCSC:P42772 CDKN2B

Reference Transcript

Other Identifiers

1030

11726507_a_at

11726508_a_at

11736163_a_at

1607_at

17092901

207530_PM_s_at

207530_s_at

236313_PM_at

236313_at

3201459

3201460

3201489

3201490

3201491

3201492

3201494

3201495

3201496

3201497

3201498

3201499

3201500

3201501

34624_at

54310_at

73132_r_at

75652_at

8160452

A_23_P216812

A_24_P360674

GE81459

GO:0004861

GO:0005515

GO:0005634

GO:0005737

GO:0005829

GO:0007179

GO:0008285

GO:0019901

GO:0030154

GO:0030219

GO:0030511

GO:0031670

GO:0048536

GO:0048856

GO:0050680

GO:0070316

GO:0071460

GO:0090398

GO:0098772

GO:2000045

GO:2000134

HMNXSV003044699

Hs.44565.0.A1_3p_at

ILMN_1670111

ILMN_1723198

ILMN_2376723

L36844_at

PH_hs_0004184

TC09000965.hg

g11386206_3p_a_at

Participates

as an output of

as a member of

INK4 [cytosol] (Homo sapiens)

Inferred To

Cdkn2b [cytosol] (Mus musculus)

Cdkn2b [cytosol] (Rattus norvegicus)

CDKN2B [cytosol] (Bos taurus)

CDKN2B [cytosol] (Canis familiaris)

CDKN2B [cytosol] (Gallus gallus)

CDKN2B [cytosol] (Sus scrofa)

cdkn2b [cytosol] (Xenopus tropicalis)

cdkn2a/b [cytosol] (Danio rerio)

Cross References

RefSeq

NP_004927.2, NP_511042.1

ENSEMBL

ENST00000380142, ENSP00000276925, ENSP00000369487, ENST00000276925, ENSG00000147883

OpenTargets

ENSG00000147883

GeneCards

CDKN2B

HPA

ENSG00000147883-CDKN2B

PRO

P42772

Pharos - Targets

P42772

Orphanet

CDKN2B

HMDB Protein

HMDBP14516

Interactors (17)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P11802 CDK4	3	p-T172-CDK4 [nucleoplasm] (R-HSA-113830) CDK4 [nucleoplasm] (R-HSA-113843) CDK4 [cytosol] (R-HSA-68330)	0.968	22
UniProt:Q00534 CDK6	3	p-T177-CDK6 [nucleoplasm] (R-HSA-69628) CDK6 [nucleoplasm] (R-HSA-141283) CDK6 [cytosol] (R-HSA-68336)	0.919	19
UniProt:Q13077 TRAF1	3	TRAF1 [cytosol] (R-HSA-5634163) TRAF1(1-163) [cytosol] (R-HSA-5634199) TRAF1(164-416) [cytosol] (R-HSA-5634204)	0.735	7
UniProt:P43364 MAGAB			0.666	4
UniProt:Q00537 CDK17			0.556	3
UniProt:Q53H96 PYCR3	1	PYCR3 [cytosol] (R-HSA-6783934)	0.556	3
UniProt:Q9BVN2 RUSC1			0.556	3
UniProt:Q0VD86 INCA1			0.556	3
UniProt:Q6P9H4 CNKR3			0.556	3
UniProt:Q9NZD8 SPG21			0.556	6
UniProt:A6ZKI3 RTL8C			0.556	3
UniProt:Q9GZT8 NIF3L			0.556	3
IntAct:EBI-10171584 80125			0.556	3
UniProt:Q9NRD5 PICK1	2	PICK1 [plasma membrane] (R-HSA-416989) PICK1 [endocytic vesicle membrane] (R-HSA-417017)	0.556	3
UniProt:Q9UI12 ATP6V1H	2	ATP6V1H [cytosol] (R-HSA-167578) ATP6V1H [plasma membrane] (R-HSA-167602)	0.556	3
UniProt:P24863 CCNC	1	CCNC [nucleoplasm] (R-HSA-212418)	0.556	3
UniProt:P15056 BRAF	20	p-S,T-BRAF [cytosol] (R-HSA-169856) BRAF(1-380)-MACF1(600-7388)fusion [cytosol] (R-HSA-6802402) p-BRAF(1-380)-MACF1(600-7388) fusion [cytosol] (R-HSA-6802536) BRAF E501G [cytosol] (R-HSA-9651132) BRAF D594N [cytosol] (R-HSA-6802299) BRAF D638E [cytosol] (R-HSA-9651125) BRAF G596R [cytosol] (R-HSA-6802385) BRAF D594V [cytosol] (R-HSA-6802305) BRAF G596V [cytosol] (R-HSA-9651138) BRAF G466E [cytosol] (R-HSA-6802374) BRAF D594G [cytosol] (R-HSA-6802295) BRAF L505H [cytosol] (R-HSA-9648845) BRAF F595L [cytosol] (R-HSA-6802316) BRAF L597V [cytosol] (R-HSA-6802397) BRAF G464E [cytosol] (R-HSA-6802369) BRAF N581D [cytosol] (R-HSA-9651152) BRAF E586K [cytosol] (R-HSA-6802308) BRAF V600K [cytosol] (R-HSA-6802502) BRAF A246P [cytosol] (R-HSA-9651123) BRAF G469V [cytosol] (R-HSA-9648620)	0.553	4

Cite Us!