Phosphorylation of CBL (EGFR:GRB2:CBL)

Stable Identifier
R-HSA-183058
Type
Reaction [transition]
Species
Homo sapiens
Compartment
ReviewStatus
5/5
Locations in the PathwayBrowser
General
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EGF (and indeed FGF, PDGF and NGF) stimulation results in CBL phosphorylation on Tyr-371. Phosphorylation is necessary for CBL to exhibit ubiquitin ligase activity.
Participants
Participates
Catalyst Activity

protein tyrosine kinase activity of EGF-like ligands:p-6Y-EGFR:CBL:GRB2 [plasma membrane]

Orthologous Events
Authored
Reviewed
Created
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