Monoubiquitinated N-myristoyl GAG polyprotein is targeted to the late endosomal vesicle membrane by the ESCRT-I complex

Stable Identifier
R-HSA-184269
Type
Reaction [transition]
Species
Homo sapiens
Related Species
Human immunodeficiency virus 1
Compartment
ReviewStatus
5/5
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Monoubiquitinated N-myristoyl Gag polyprotein associates with the ESCRT-1 complex at an endosomal membrane (Eastman et al. 2005; Martin-Serrano et al. 2003; Stuchell et al. 2004).
Literature References
PubMed ID Title Journal Year
15218037 The human endosomal sorting complex required for transport (ESCRT-I) and its role in HIV-1 budding

Ghaffarian, S, Stuchell, MD, Garrus, JE, Sundquist, WI, McKinnon, R, Muller, B, Stray, KM, Krausslich, HG, Morham, SG

J Biol Chem 2004
12663786 Role of ESCRT-I in retroviral budding

Bieniasz, PD, Martin-Serrano, J, Zang, T

J Virol 2003
15509564 Identification of human VPS37C, a component of endosomal sorting complex required for transport-I important for viral budding

Chung, W, Bieniasz, PD, Eastman, SW, Martin-Serrano, J, Zang, T

J Biol Chem 2005
Participants
Participates
Catalyst Activity

protein transmembrane transporter activity of ESCRT-I [endosome membrane]

Disease
Name Identifier Synonyms
Human immunodeficiency virus infectious disease DOID:526 HIV infection
Authored
Reviewed
Created
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