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VPS37B [endosome membrane]
Stable Identifier
R-HSA-184293
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
endosome membrane
Locations in the PathwayBrowser
Expand all
Autophagy (Homo sapiens)
Late endosomal microautophagy (Homo sapiens)
Substrate translocates into late endosomal lumen (Homo sapiens)
ESCRT-I [endosome membrane] (Homo sapiens)
VPS37 [endosome membrane] (Homo sapiens)
VPS37B [endosome membrane] (Homo sapiens)
Disease (Homo sapiens)
Infectious disease (Homo sapiens)
Viral Infection Pathways (Homo sapiens)
HCMV Infection (Homo sapiens)
HCMV Late Events (Homo sapiens)
HCMV Final Envelopment (Homo sapiens)
ESCRT Regulator Complex [cytosol] (Homo sapiens)
ESCRT-I [endosome membrane] (Homo sapiens)
VPS37 [endosome membrane] (Homo sapiens)
VPS37B [endosome membrane] (Homo sapiens)
HCMV Formation of Final Envelopment Complex (Homo sapiens)
ESCRT Regulator Complex [cytosol] (Homo sapiens)
ESCRT-I [endosome membrane] (Homo sapiens)
VPS37 [endosome membrane] (Homo sapiens)
VPS37B [endosome membrane] (Homo sapiens)
HIV Infection (Homo sapiens)
HIV Life Cycle (Homo sapiens)
Late Phase of HIV Life Cycle (Homo sapiens)
Assembly Of The HIV Virion (Homo sapiens)
Synthesis And Processing Of GAG, GAGPOL Polyproteins (Homo sapiens)
Membrane binding and targetting of GAG proteins (Homo sapiens)
Monoubiquitinated N-myristoyl GAG polyprotein is targeted to the late endosomal vesicle membrane by the ESCRT-I complex (Homo sapiens)
ESCRT-I [endosome membrane] (Homo sapiens)
VPS37 [endosome membrane] (Homo sapiens)
VPS37B [endosome membrane] (Homo sapiens)
Transport of GAG to the Plasma Membrane (Homo sapiens)
ESCRT-I [endosome membrane] (Homo sapiens)
VPS37 [endosome membrane] (Homo sapiens)
VPS37B [endosome membrane] (Homo sapiens)
Budding and maturation of HIV virion (Homo sapiens)
HIV Virion Budding (Homo sapiens)
Virion Budding Complex [plasma membrane] (Homo sapiens)
ESCRT-I [endosome membrane] (Homo sapiens)
VPS37 [endosome membrane] (Homo sapiens)
VPS37B [endosome membrane] (Homo sapiens)
Recruitment Of HIV Virion Budding Machinery (Homo sapiens)
ESCRT-I [endosome membrane] (Homo sapiens)
VPS37 [endosome membrane] (Homo sapiens)
VPS37B [endosome membrane] (Homo sapiens)
Virion Budding Complex [plasma membrane] (Homo sapiens)
ESCRT-I [endosome membrane] (Homo sapiens)
VPS37 [endosome membrane] (Homo sapiens)
VPS37B [endosome membrane] (Homo sapiens)
Vesicle-mediated transport (Homo sapiens)
Membrane Trafficking (Homo sapiens)
Endosomal Sorting Complex Required For Transport (ESCRT) (Homo sapiens)
Cargo Recognition And Sorting (Homo sapiens)
ESCRT-I [endosome membrane] (Homo sapiens)
VPS37 [endosome membrane] (Homo sapiens)
VPS37B [endosome membrane] (Homo sapiens)
ESCRT-I/Cargo Complex [endosome membrane] (Homo sapiens)
ESCRT-I [endosome membrane] (Homo sapiens)
VPS37 [endosome membrane] (Homo sapiens)
VPS37B [endosome membrane] (Homo sapiens)
Cargo Sequestration (Homo sapiens)
ESCRT-I [endosome membrane] (Homo sapiens)
VPS37 [endosome membrane] (Homo sapiens)
VPS37B [endosome membrane] (Homo sapiens)
ESCRT-I/Cargo Complex [endosome membrane] (Homo sapiens)
ESCRT-I [endosome membrane] (Homo sapiens)
VPS37 [endosome membrane] (Homo sapiens)
VPS37B [endosome membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q9H9H4 VPS37B
Gene Names
VPS37B
Chain
chain:1-285
Reference Genes
BioGPS Gene:79720 VPS37B
COSMIC (genes):VPS37B VPS37B
CTD Gene:79720 VPS37B
dbSNP Gene:79720 VPS37B
ENSEMBL:ENSG00000139722 VPS37B
HGNC:25754 VPS37B
KEGG:hsa:79720 VPS37B
Monarch:79720 VPS37B
NCBI Gene:79720 VPS37B
OMIM:610037 VPS37B
UCSC:Q9H9H4 VPS37B
Reference Transcript
RefSeq:NM_024667.2 VPS37B
Other Identifiers
11716518_at
16771805
221704_PM_s_at
221704_s_at
3475839
3475840
3475841
3475842
3475843
3475847
3475849
3475850
3475851
3475853
3475854
3475865
3475866
3475867
3475870
3475871
57234_at
68715_at
7967331
79720
A_23_P150876
GE537163
GE85840
GO:0000813
GO:0005515
GO:0005737
GO:0005768
GO:0005886
GO:0006612
GO:0006623
GO:0006886
GO:0006914
GO:0009056
GO:0010008
GO:0015031
GO:0016020
GO:0016192
GO:0016236
GO:0019076
GO:0030496
GO:0031410
GO:0031902
GO:0036258
GO:0039702
GO:0043162
GO:0043226
GO:0043328
GO:0048306
GO:0061024
GO:0070062
GO:0090148
GO:1903774
HMNXSV003005834
ILMN_1710427
PH_hs_0004495
PH_hs_0037330
TC12002080.hg
g13543447_3p_s_at
Participates
as a member of
VPS37 [endosome membrane] (Homo sapiens)
Inferred To
SRN2 [endosome membrane]
(Saccharomyces cerevisiae)
Vps37b [endosome membrane]
(Mus musculus)
Vps37b [endosome membrane]
(Rattus norvegicus)
Vps37B [endosome membrane]
(Drosophila melanogaster)
vps37 [endosome membrane]
(Dictyostelium discoideum)
vps-37 [endosome membrane]
(Caenorhabditis elegans)
VPS37B [endosome membrane]
(Bos taurus)
VPS37B [endosome membrane]
(Canis familiaris)
VPS37B [endosome membrane]
(Gallus gallus)
VPS37B [endosome membrane]
(Sus scrofa)
vps37ba [endosome membrane]
(Danio rerio)
Cross References
RefSeq
NP_078943.1
ENSEMBL
ENST00000267202
,
ENSP00000267202
OpenTargets
ENSG00000139722
HPA
ENSG00000139722-VPS37B
PRO
Q9H9H4
Pharos - Targets
Q9H9H4
GlyGen
Q9H9H4
PDB
6VME
Interactors (11)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:O43639 NCK2
1
NCK2 [cytosol]
(R-HSA-204885)
0.718
6
UniProt:O14964 HGS
2
HGS [cytosol]
(R-HSA-182954)
HGS [phagocytic vesicle lumen]
(R-HSA-9635660)
0.718
6
UniProt:Q13895 BYSL
2
BYSL [nucleoplasm]
(R-HSA-6791526)
BYSL [cytosol]
(R-HSA-6791518)
0.718
8
UniProt:P07992 ERCC1
2
Ub-ERCC1 [nucleoplasm]
(R-HSA-5696473)
ERCC1 [nucleoplasm]
(R-HSA-54427)
0.666
4
UniProt:P62993 GRB2
1
GRB2 [cytosol]
(R-HSA-8983328)
0.643
4
UniProt:P54646 PRKAA2
4
PRKAA2 [cytosol]
(R-HSA-200405)
p-T172-PRKAA2 [cytosol]
(R-HSA-200417)
p-T172-PRKAA2 [nucleoplasm]
(R-HSA-164171)
PRKAA2 [nucleoplasm]
(R-HSA-163682)
0.556
3
UniProt:Q8IYI6 EXOC8
2
EXOC8 [plasma membrane]
(R-HSA-264948)
EXOC8 [cytosol]
(R-HSA-5623388)
0.556
3
UniProt:Q08117 TLE5
1
AES [nucleoplasm]
(R-HSA-4648963)
0.556
3
UniProt:P47897 QARS1
2
QARS [cytosol]
(R-HSA-379615)
QARS [mitochondrial matrix]
(R-HSA-379592)
0.556
3
UniProt:O60341 KDM1A
1
KDM1A [nucleoplasm]
(R-HSA-996769)
0.556
3
UniProt:Q6P1J9 CDC73
1
CDC73 [nucleoplasm]
(R-HSA-3322360)
0.556
3
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