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VPS37A [endosome membrane]
Stable Identifier
R-HSA-184333
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
endosome membrane
Locations in the PathwayBrowser
Expand all
Autophagy (Homo sapiens)
Late endosomal microautophagy (Homo sapiens)
Substrate translocates into late endosomal lumen (Homo sapiens)
ESCRT-I [endosome membrane] (Homo sapiens)
VPS37 [endosome membrane] (Homo sapiens)
VPS37A [endosome membrane] (Homo sapiens)
Disease (Homo sapiens)
Infectious disease (Homo sapiens)
Viral Infection Pathways (Homo sapiens)
HCMV Infection (Homo sapiens)
HCMV Late Events (Homo sapiens)
HCMV Final Envelopment (Homo sapiens)
ESCRT Regulator Complex [cytosol] (Homo sapiens)
ESCRT-I [endosome membrane] (Homo sapiens)
VPS37 [endosome membrane] (Homo sapiens)
VPS37A [endosome membrane] (Homo sapiens)
HCMV Formation of Final Envelopment Complex (Homo sapiens)
ESCRT Regulator Complex [cytosol] (Homo sapiens)
ESCRT-I [endosome membrane] (Homo sapiens)
VPS37 [endosome membrane] (Homo sapiens)
VPS37A [endosome membrane] (Homo sapiens)
HIV Infection (Homo sapiens)
HIV Life Cycle (Homo sapiens)
Late Phase of HIV Life Cycle (Homo sapiens)
Assembly Of The HIV Virion (Homo sapiens)
Synthesis And Processing Of GAG, GAGPOL Polyproteins (Homo sapiens)
Membrane binding and targetting of GAG proteins (Homo sapiens)
Monoubiquitinated N-myristoyl GAG polyprotein is targeted to the late endosomal vesicle membrane by the ESCRT-I complex (Homo sapiens)
ESCRT-I [endosome membrane] (Homo sapiens)
VPS37 [endosome membrane] (Homo sapiens)
VPS37A [endosome membrane] (Homo sapiens)
Transport of GAG to the Plasma Membrane (Homo sapiens)
ESCRT-I [endosome membrane] (Homo sapiens)
VPS37 [endosome membrane] (Homo sapiens)
VPS37A [endosome membrane] (Homo sapiens)
Budding and maturation of HIV virion (Homo sapiens)
HIV Virion Budding (Homo sapiens)
Virion Budding Complex [plasma membrane] (Homo sapiens)
ESCRT-I [endosome membrane] (Homo sapiens)
VPS37 [endosome membrane] (Homo sapiens)
VPS37A [endosome membrane] (Homo sapiens)
Recruitment Of HIV Virion Budding Machinery (Homo sapiens)
ESCRT-I [endosome membrane] (Homo sapiens)
VPS37 [endosome membrane] (Homo sapiens)
VPS37A [endosome membrane] (Homo sapiens)
Virion Budding Complex [plasma membrane] (Homo sapiens)
ESCRT-I [endosome membrane] (Homo sapiens)
VPS37 [endosome membrane] (Homo sapiens)
VPS37A [endosome membrane] (Homo sapiens)
Vesicle-mediated transport (Homo sapiens)
Membrane Trafficking (Homo sapiens)
Endosomal Sorting Complex Required For Transport (ESCRT) (Homo sapiens)
Cargo Recognition And Sorting (Homo sapiens)
ESCRT-I [endosome membrane] (Homo sapiens)
VPS37 [endosome membrane] (Homo sapiens)
VPS37A [endosome membrane] (Homo sapiens)
ESCRT-I/Cargo Complex [endosome membrane] (Homo sapiens)
ESCRT-I [endosome membrane] (Homo sapiens)
VPS37 [endosome membrane] (Homo sapiens)
VPS37A [endosome membrane] (Homo sapiens)
Cargo Sequestration (Homo sapiens)
ESCRT-I [endosome membrane] (Homo sapiens)
VPS37 [endosome membrane] (Homo sapiens)
VPS37A [endosome membrane] (Homo sapiens)
ESCRT-I/Cargo Complex [endosome membrane] (Homo sapiens)
ESCRT-I [endosome membrane] (Homo sapiens)
VPS37 [endosome membrane] (Homo sapiens)
VPS37A [endosome membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q8NEZ2 VPS37A
Gene Names
VPS37A, HCRP1
Chain
chain:1-397
Reference Genes
BioGPS Gene:137492 VPS37A
COSMIC (genes):VPS37A VPS37A
CTD Gene:137492 VPS37A
dbSNP Gene:137492 VPS37A
ENSEMBL:ENSG00000155975 VPS37A
HGNC:24928 VPS37A
KEGG:hsa:137492 VPS37A
Monarch:137492 VPS37A
NCBI Gene:137492 VPS37A
OMIM:609927 VPS37A
UCSC:Q8NEZ2 VPS37A
Reference Transcript
RefSeq:XM_017013026.1 VPS37A
RefSeq:XM_017013022.1 VPS37A
RefSeq:NM_152415.2 VPS37A
RefSeq:XM_017013021.1 VPS37A
RefSeq:NM_001145152.1 VPS37A
Other Identifiers
11725342_a_at
11725343_a_at
11725344_a_at
137492
17066036
225378_PM_at
225378_at
228024_PM_at
228024_at
3087559
3087560
3087561
3087562
3087564
3087567
3087568
3087569
3087570
3087571
3087572
3087573
3087574
3087576
3087577
3087578
3087579
3087582
3087585
3087586
3087589
3087590
3087591
3087592
3087593
3087594
3087595
3087596
3087597
3087598
3087599
3087604
61863_at
63312_r_at
65242_at
74777_at
8144774
84345_at
84348_g_at
A_14_P106165
A_23_P366328
A_24_P941649
A_33_P3303850
GE53583
GO:0000813
GO:0005515
GO:0005634
GO:0005654
GO:0005768
GO:0005813
GO:0005815
GO:0005829
GO:0006612
GO:0006623
GO:0006886
GO:0006914
GO:0009056
GO:0010008
GO:0015031
GO:0016020
GO:0016192
GO:0016236
GO:0031410
GO:0031902
GO:0036258
GO:0039702
GO:0043162
GO:0043226
GO:0043231
GO:0043328
GO:0061024
GO:0090148
HMNXSV003021241
HMNXSV003048901
Hs.101617.0.A1_3p_at
Hs.290855.0.S1_3p_at
ILMN_1711139
ILMN_2161832
PH_hs_0028158
TC08000126.hg
Participates
as a member of
VPS37 [endosome membrane] (Homo sapiens)
Inferred To
VPS37A [endosome membrane]
(Bos taurus)
VPS37A [endosome membrane]
(Canis familiaris)
VPS37A [endosome membrane]
(Gallus gallus)
VPS37A [endosome membrane]
(Rattus norvegicus)
VPS37A [endosome membrane]
(Sus scrofa)
vps37a [endosome membrane]
(Danio rerio)
SRN2 [endosome membrane]
(Saccharomyces cerevisiae)
vps37 [endosome membrane]
(Dictyostelium discoideum)
Vps37a [endosome membrane]
(Mus musculus)
Vsp37A [endosome membrane]
(Drosophila melanogaster)
Cross References
RefSeq
XP_016868515.1
,
NP_001138624.1
,
XP_016868511.1
,
XP_016868510.1
,
NP_689628.2
ENSEMBL
ENST00000324849
,
ENSP00000412824
,
ENSP00000318629
,
ENST00000425020
,
ENST00000521829
,
ENSP00000429680
OpenTargets
ENSG00000155975
HPA
ENSG00000155975-VPS37A
PRO
Q8NEZ2
Pharos - Targets
Q8NEZ2
GlyGen
Q8NEZ2
Orphanet
VPS37A
PDB
8E22
Interactors (6)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P06396 GSN
7
GSN [cytosol]
(R-HSA-350275)
GSN(28-403) [cytosol]
(R-HSA-201618)
GSN(404-782) [cytosol]
(R-HSA-350272)
GSN [secretory granule lumen]
(R-HSA-6801486)
GSN [extracellular region]
(R-HSA-6806510)
GSN [ficolin-1-rich granule lumen]
(R-HSA-6801465)
GSN(200-270) [extracellular region]
(R-HSA-976940)
0.556
3
UniProt:O76024 WFS1
3
WFS1 [endoplasmic reticulum lumen]
(R-HSA-8956747)
p-WFS1 [endoplasmic reticulum lumen]
(R-HSA-8956998)
WFS1 [endoplasmic reticulum membrane]
(R-HSA-535474)
0.556
3
UniProt:P35240 NF2
1
NF2 [plasma membrane]
(R-HSA-5669168)
0.556
3
UniProt:O43464 HTRA2
1
HTRA2 [mitochondrial intermembrane space]
(R-HSA-56655)
0.556
3
UniProt:P42858 HTT
1
HTT [nucleoplasm]
(R-HSA-9023590)
0.556
6
UniProt:P54252 ATXN3
2
ATXN3 [nucleoplasm]
(R-HSA-6783285)
ATXN3 [cytosol]
(R-HSA-5625607)
0.556
3
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