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VPS28 [endosome membrane]
Stable Identifier
R-HSA-184342
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
endosome membrane
Locations in the PathwayBrowser
Expand all
Autophagy (Homo sapiens)
Late endosomal microautophagy (Homo sapiens)
Substrate translocates into late endosomal lumen (Homo sapiens)
ESCRT-I [endosome membrane] (Homo sapiens)
VPS28 [endosome membrane] (Homo sapiens)
Disease (Homo sapiens)
Infectious disease (Homo sapiens)
Viral Infection Pathways (Homo sapiens)
HCMV Infection (Homo sapiens)
HCMV Late Events (Homo sapiens)
HCMV Final Envelopment (Homo sapiens)
ESCRT Regulator Complex [cytosol] (Homo sapiens)
ESCRT-I [endosome membrane] (Homo sapiens)
VPS28 [endosome membrane] (Homo sapiens)
HCMV Formation of Final Envelopment Complex (Homo sapiens)
ESCRT Regulator Complex [cytosol] (Homo sapiens)
ESCRT-I [endosome membrane] (Homo sapiens)
VPS28 [endosome membrane] (Homo sapiens)
HIV Infection (Homo sapiens)
HIV Life Cycle (Homo sapiens)
Late Phase of HIV Life Cycle (Homo sapiens)
Assembly Of The HIV Virion (Homo sapiens)
Synthesis And Processing Of GAG, GAGPOL Polyproteins (Homo sapiens)
Membrane binding and targetting of GAG proteins (Homo sapiens)
Monoubiquitinated N-myristoyl GAG polyprotein is targeted to the late endosomal vesicle membrane by the ESCRT-I complex (Homo sapiens)
ESCRT-I [endosome membrane] (Homo sapiens)
VPS28 [endosome membrane] (Homo sapiens)
Transport of GAG to the Plasma Membrane (Homo sapiens)
ESCRT-I [endosome membrane] (Homo sapiens)
VPS28 [endosome membrane] (Homo sapiens)
Budding and maturation of HIV virion (Homo sapiens)
HIV Virion Budding (Homo sapiens)
Virion Budding Complex [plasma membrane] (Homo sapiens)
ESCRT-I [endosome membrane] (Homo sapiens)
VPS28 [endosome membrane] (Homo sapiens)
Recruitment Of HIV Virion Budding Machinery (Homo sapiens)
ESCRT-I [endosome membrane] (Homo sapiens)
VPS28 [endosome membrane] (Homo sapiens)
Virion Budding Complex [plasma membrane] (Homo sapiens)
ESCRT-I [endosome membrane] (Homo sapiens)
VPS28 [endosome membrane] (Homo sapiens)
Vesicle-mediated transport (Homo sapiens)
Membrane Trafficking (Homo sapiens)
Endosomal Sorting Complex Required For Transport (ESCRT) (Homo sapiens)
Cargo Recognition And Sorting (Homo sapiens)
ESCRT-I [endosome membrane] (Homo sapiens)
VPS28 [endosome membrane] (Homo sapiens)
ESCRT-I/Cargo Complex [endosome membrane] (Homo sapiens)
ESCRT-I [endosome membrane] (Homo sapiens)
VPS28 [endosome membrane] (Homo sapiens)
Cargo Sequestration (Homo sapiens)
ESCRT-I [endosome membrane] (Homo sapiens)
VPS28 [endosome membrane] (Homo sapiens)
ESCRT-I/Cargo Complex [endosome membrane] (Homo sapiens)
ESCRT-I [endosome membrane] (Homo sapiens)
VPS28 [endosome membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q9UK41 VPS28
Gene Names
VPS28
Chain
chain:1-221
Reference Genes
COSMIC (genes):VPS28 VPS28
dbSNP Gene:51160 VPS28
ENSEMBL:ENSG00000160948 VPS28
Participates
as a component of
ESCRT-I [endosome membrane] (Homo sapiens)
Inferred To
Ghost homologue of VPS28 [endosome membrane]
(Gallus gallus)
vps-28 [endosome membrane]
(Caenorhabditis elegans)
Vps28 [endosome membrane]
(Drosophila melanogaster)
Vps28 [endosome membrane]
(Mus musculus)
Vps28 [endosome membrane]
(Rattus norvegicus)
vps28 [endosome membrane]
(Danio rerio)
vps28 [endosome membrane]
(Dictyostelium discoideum)
VPS28 [endosome membrane]
(Bos taurus)
VPS28 [endosome membrane]
(Canis familiaris)
VPS28 [endosome membrane]
(Saccharomyces cerevisiae)
VPS28 [endosome membrane]
(Sus scrofa)
Interactors (4)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P42858 HTT
1
HTT [nucleoplasm]
(R-HSA-9023590)
0.666
16
UniProt:P14373 TRIM27
2
TRIM27 [cytosol]
(R-HSA-8851002)
TRIM27 [nucleoplasm]
(R-HSA-2997690)
0.556
3
UniProt:Q08379 GOLGA2
3
p-S37-GOLGA2 [Golgi membrane]
(R-HSA-2172179)
GOLGA2 [endoplasmic reticulum-Golgi intermediate compartment membrane]
(R-HSA-2167933)
GOLGA2 [Golgi membrane]
(R-HSA-6808764)
0.556
6
UniProt:P62993 GRB2
1
GRB2 [cytosol]
(R-HSA-8983328)
0.527
2
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