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NEUROD1 [nucleoplasm]
Stable Identifier
R-HSA-186689
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
NeuroD1/Beta2
Icon
Locations in the PathwayBrowser
Expand all
Developmental Biology (Homo sapiens)
Regulation of beta-cell development (Homo sapiens)
Regulation of gene expression in beta cells (Homo sapiens)
NEUROD1- and PDX1-dependent synthesis of glucokinase (GCK) protein (Homo sapiens)
NEUROD1 [nucleoplasm] (Homo sapiens)
Regulation of gene expression in endocrine-committed (NEUROG3+) progenitor cells (Homo sapiens)
NEUROG3-dependent synthesis of NEUROD1 (Homo sapiens)
NEUROD1 [nucleoplasm] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q13562 NEUROD1
Gene Names
NEUROD1, BHLHA3, NEUROD
Chain
chain:1-356
Reference Genes
BioGPS Gene:4760 NEUROD1
COSMIC (genes):NEUROD1 NEUROD1
CTD Gene:4760 NEUROD1
dbSNP Gene:4760 NEUROD1
ENSEMBL:ENSG00000162992 NEUROD1
ENSEMBL_homo_sapiens_GENE:ENSG00000162992.5 NEUROD1
HGNC:7762 NEUROD1
KEGG Gene (Homo sapiens):4760 NEUROD1
Monarch:4760 NEUROD1
NCBI Gene:4760 NEUROD1
OMIM:601724 NEUROD1
UCSC:Q13562 NEUROD1
Reference Transcript
RefSeq:NM_002500.4 NEUROD1
Other Identifiers
11724556_at
11724557_at
1556057_PM_s_at
1556057_s_at
206282_PM_at
206282_at
2590492
2590493
2590497
36768_at
4760
8057480
A_23_P209484
A_33_P3285965
D82347_at
GE57323
GO:0000785
GO:0000978
GO:0000981
GO:0001228
GO:0003326
GO:0003329
GO:0003677
GO:0003682
GO:0003690
GO:0003700
GO:0005515
GO:0005634
GO:0005654
GO:0005694
GO:0005737
GO:0006351
GO:0006355
GO:0006366
GO:0006913
GO:0007259
GO:0007263
GO:0007399
GO:0007423
GO:0009410
GO:0009749
GO:0009952
GO:0012501
GO:0021542
GO:0021549
GO:0022008
GO:0022600
GO:0023019
GO:0023052
GO:0030073
GO:0030154
GO:0030902
GO:0031018
GO:0035881
GO:0035883
GO:0042593
GO:0043010
GO:0043065
GO:0043226
GO:0043565
GO:0045165
GO:0045597
GO:0045664
GO:0045666
GO:0045893
GO:0045944
GO:0046426
GO:0046982
GO:0046983
GO:0048562
GO:0048839
GO:0048856
GO:0050796
GO:0051091
GO:0060730
GO:0061564
GO:0061629
GO:0070888
GO:0071333
GO:0090575
GO:0140110
GO:1990837
GO:2000675
GO:2000679
HMNXSV003016181
Hs2.407438.1.S1_3p_s_at
ILMN_1669425
PH_hs_0004195
TC02004731.hg
TC02005050.hg
U50822_rna1_s_at
g4505376_3p_at
Participates
as an output of
NEUROG3-dependent synthesis of NEUROD1 (Homo sapiens)
This entity regulates
Positively
NEUROD1- and PDX1-dependent synthesis of glucokinase (GCK) protein
(Homo sapiens)
Cross References
RefSeq
NP_002491.2
OpenTargets
ENSG00000162992
GeneCards
Q13562
HPA
ENSG00000162992-NEUROD1
Ensembl
ENSP00000295108
,
ENSP00000506907
,
ENSG00000162992
,
ENSP00000507492
,
ENST00000683430
,
ENST00000295108
,
ENST00000684079
PRO
Q13562
Pharos - Targets
Q13562
Orphanet
16540
Interactors (13)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q99081-3 TCF12
0.666
4
UniProt:P15884-3 TCF4
0.556
3
UniProt:Q9BVL2 NUP58
0.556
3
UniProt:P54652 HSPA2
2
HSPA2 [cytosol]
(R-HSA-3371408)
HSPA2 [nucleoplasm]
(R-HSA-912480)
0.556
3
UniProt:P28331-2 NDUFS1
0.556
3
UniProt:O14901 KLF11
0.556
3
UniProt:O43464 HTRA2
1
HTRA2 [mitochondrial intermembrane space]
(R-HSA-56655)
0.556
3
IntAct:EBI-25847655 CCSB
0.556
3
UniProt:Q0VDC6 Q0VDC6
0.556
3
UniProt:P41219 PERI
0.556
3
UniProt:P42858 HTT
1
HTT [nucleoplasm]
(R-HSA-9023590)
0.556
6
UniProt:P15884 TCF4
1
TCF4 [nucleoplasm]
(R-HSA-445672)
0.527
2
UniProt:Q9GZZ8 LACRT
0.527
2
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