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Phospho-alpha receptor homodimer [plasma membrane]
Stable Identifier
R-HSA-186816
Type
Complex
Species
Homo sapiens
Compartment
plasma membrane
Locations in the PathwayBrowser
Expand all
Disease (Homo sapiens)
Diseases of signal transduction by growth factor receptors and second messengers (Homo sapiens)
PI3K/AKT Signaling in Cancer (Homo sapiens)
Constitutive Signaling by Aberrant PI3K in Cancer (Homo sapiens)
PI3K inhibitors block PI3K catalytic activity (Homo sapiens)
PI3K Inhibitors:PI3K [cytosol] (Homo sapiens)
PI3K mutants,Activator:PI3K [plasma membrane] (Homo sapiens)
Activator:PI3K [plasma membrane] (Homo sapiens)
PDGF:Phospho-PDGF receptor dimer:PI3K [plasma membrane] (Homo sapiens)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Homo sapiens)
Phospho- PDGF receptor dimer [plasma membrane] (Homo sapiens)
Phospho-alpha receptor homodimer [plasma membrane] (Homo sapiens)
PI3K mutants,Activator:PI3K [plasma membrane] (Homo sapiens)
Activator:PI3K [plasma membrane] (Homo sapiens)
PDGF:Phospho-PDGF receptor dimer:PI3K [plasma membrane] (Homo sapiens)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Homo sapiens)
Phospho- PDGF receptor dimer [plasma membrane] (Homo sapiens)
Phospho-alpha receptor homodimer [plasma membrane] (Homo sapiens)
Signal Transduction (Homo sapiens)
Intracellular signaling by second messengers (Homo sapiens)
PIP3 activates AKT signaling (Homo sapiens)
Negative regulation of the PI3K/AKT network (Homo sapiens)
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling (Homo sapiens)
PI3K phosphorylates PIP2 to PIP3 (Homo sapiens)
Activator:PI3K [plasma membrane] (Homo sapiens)
PDGF:Phospho-PDGF receptor dimer:PI3K [plasma membrane] (Homo sapiens)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Homo sapiens)
Phospho- PDGF receptor dimer [plasma membrane] (Homo sapiens)
Phospho-alpha receptor homodimer [plasma membrane] (Homo sapiens)
PI3K phosphorylates PIP2 to PIP3 (Homo sapiens)
Activator:PI3K [plasma membrane] (Homo sapiens)
PDGF:Phospho-PDGF receptor dimer:PI3K [plasma membrane] (Homo sapiens)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Homo sapiens)
Phospho- PDGF receptor dimer [plasma membrane] (Homo sapiens)
Phospho-alpha receptor homodimer [plasma membrane] (Homo sapiens)
MAPK family signaling cascades (Homo sapiens)
MAPK1/MAPK3 signaling (Homo sapiens)
RAF/MAP kinase cascade (Homo sapiens)
RAS GEFs promote RAS nucleotide exchange (Homo sapiens)
RAS GEFs [plasma membrane] (Homo sapiens)
PDGF:Phospho-PDGF receptor dimer:Grb2:Sos1 [plasma membrane] (Homo sapiens)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Homo sapiens)
Phospho- PDGF receptor dimer [plasma membrane] (Homo sapiens)
Phospho-alpha receptor homodimer [plasma membrane] (Homo sapiens)
Signaling by Receptor Tyrosine Kinases (Homo sapiens)
Signaling by PDGF (Homo sapiens)
Autophosphorylation of PDGF alpha receptors (Homo sapiens)
Phospho PDGF alpha receptor:PDGF dimers [plasma membrane] (Homo sapiens)
Phospho-alpha receptor homodimer [plasma membrane] (Homo sapiens)
Downstream signal transduction (Homo sapiens)
Activated PLC gamma dissociates from the PDGF receptor (Homo sapiens)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Homo sapiens)
Phospho- PDGF receptor dimer [plasma membrane] (Homo sapiens)
Phospho-alpha receptor homodimer [plasma membrane] (Homo sapiens)
PDGF:p-PDGFR dimer:p-PLCgamma [plasma membrane] (Homo sapiens)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Homo sapiens)
Phospho- PDGF receptor dimer [plasma membrane] (Homo sapiens)
Phospho-alpha receptor homodimer [plasma membrane] (Homo sapiens)
Activation of Src (Homo sapiens)
PDGF:Phospho-PDGF receptor dimer:MyrG-SRC [plasma membrane] (Homo sapiens)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Homo sapiens)
Phospho- PDGF receptor dimer [plasma membrane] (Homo sapiens)
Phospho-alpha receptor homodimer [plasma membrane] (Homo sapiens)
PDGF:Phospho-PDGF receptor dimer:MyrG-p-Y419-SRC [plasma membrane] (Homo sapiens)
Phospho- PDGF receptor dimer [plasma membrane] (Homo sapiens)
Phospho-alpha receptor homodimer [plasma membrane] (Homo sapiens)
Crk binds to the active PDGF receptor (Homo sapiens)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Homo sapiens)
Phospho- PDGF receptor dimer [plasma membrane] (Homo sapiens)
Phospho-alpha receptor homodimer [plasma membrane] (Homo sapiens)
PDGF:Phospho-PDGF receptor dimer:Crk [plasma membrane] (Homo sapiens)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Homo sapiens)
Phospho- PDGF receptor dimer [plasma membrane] (Homo sapiens)
Phospho-alpha receptor homodimer [plasma membrane] (Homo sapiens)
GRB2:SOS1 complex binds to the active receptor (Homo sapiens)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Homo sapiens)
Phospho- PDGF receptor dimer [plasma membrane] (Homo sapiens)
Phospho-alpha receptor homodimer [plasma membrane] (Homo sapiens)
PDGF:Phospho-PDGF receptor dimer:Grb2:Sos1 [plasma membrane] (Homo sapiens)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Homo sapiens)
Phospho- PDGF receptor dimer [plasma membrane] (Homo sapiens)
Phospho-alpha receptor homodimer [plasma membrane] (Homo sapiens)
Grb7 binds to the active PDGF receptor (Homo sapiens)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Homo sapiens)
Phospho- PDGF receptor dimer [plasma membrane] (Homo sapiens)
Phospho-alpha receptor homodimer [plasma membrane] (Homo sapiens)
PDGF:Phospho-PDGF receptor dimer:Grb7 [plasma membrane] (Homo sapiens)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Homo sapiens)
Phospho- PDGF receptor dimer [plasma membrane] (Homo sapiens)
Phospho-alpha receptor homodimer [plasma membrane] (Homo sapiens)
Nck binds to the active PDGF receptor (Homo sapiens)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Homo sapiens)
Phospho- PDGF receptor dimer [plasma membrane] (Homo sapiens)
Phospho-alpha receptor homodimer [plasma membrane] (Homo sapiens)
PDGF:Phospho-PDGFR receptor dimer:Nck [plasma membrane] (Homo sapiens)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Homo sapiens)
Phospho- PDGF receptor dimer [plasma membrane] (Homo sapiens)
Phospho-alpha receptor homodimer [plasma membrane] (Homo sapiens)
PI3-kinase binds to the active receptor (Homo sapiens)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Homo sapiens)
Phospho- PDGF receptor dimer [plasma membrane] (Homo sapiens)
Phospho-alpha receptor homodimer [plasma membrane] (Homo sapiens)
PDGF:Phospho-PDGF receptor dimer:PI3K [plasma membrane] (Homo sapiens)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Homo sapiens)
Phospho- PDGF receptor dimer [plasma membrane] (Homo sapiens)
Phospho-alpha receptor homodimer [plasma membrane] (Homo sapiens)
PI3K catalyses the phosphorylation of PIP2 to PIP3 (Homo sapiens)
PDGF:Phospho-PDGF receptor dimer:PI3K [plasma membrane] (Homo sapiens)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Homo sapiens)
Phospho- PDGF receptor dimer [plasma membrane] (Homo sapiens)
Phospho-alpha receptor homodimer [plasma membrane] (Homo sapiens)
PLC-gamma binds to the active receptor (Homo sapiens)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Homo sapiens)
Phospho- PDGF receptor dimer [plasma membrane] (Homo sapiens)
Phospho-alpha receptor homodimer [plasma membrane] (Homo sapiens)
PDGF:Phospho-PDGF receptor dimer:PLC-gamma [plasma membrane] (Homo sapiens)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Homo sapiens)
Phospho- PDGF receptor dimer [plasma membrane] (Homo sapiens)
Phospho-alpha receptor homodimer [plasma membrane] (Homo sapiens)
Phosphorylation of PLCgamma by PDGFR (Homo sapiens)
PDGF:Phospho-PDGF receptor dimer:PLC-gamma [plasma membrane] (Homo sapiens)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Homo sapiens)
Phospho- PDGF receptor dimer [plasma membrane] (Homo sapiens)
Phospho-alpha receptor homodimer [plasma membrane] (Homo sapiens)
PDGF:p-PDGFR dimer:p-PLCgamma [plasma membrane] (Homo sapiens)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Homo sapiens)
Phospho- PDGF receptor dimer [plasma membrane] (Homo sapiens)
Phospho-alpha receptor homodimer [plasma membrane] (Homo sapiens)
SH2 domain of Src binds to the active receptor (Homo sapiens)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Homo sapiens)
Phospho- PDGF receptor dimer [plasma membrane] (Homo sapiens)
Phospho-alpha receptor homodimer [plasma membrane] (Homo sapiens)
PDGF:Phospho-PDGF receptor dimer:MyrG-SRC [plasma membrane] (Homo sapiens)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Homo sapiens)
Phospho- PDGF receptor dimer [plasma membrane] (Homo sapiens)
Phospho-alpha receptor homodimer [plasma membrane] (Homo sapiens)
SHP2 binds to the active receptor (Homo sapiens)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Homo sapiens)
Phospho- PDGF receptor dimer [plasma membrane] (Homo sapiens)
Phospho-alpha receptor homodimer [plasma membrane] (Homo sapiens)
PDGF:Phospho-PDGF receptor dimer:SHP2 [plasma membrane] (Homo sapiens)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Homo sapiens)
Phospho- PDGF receptor dimer [plasma membrane] (Homo sapiens)
Phospho-alpha receptor homodimer [plasma membrane] (Homo sapiens)
SOS-mediated nucleotide exchange on RAS (PDGF receptor:GRB2:SOS) (Homo sapiens)
PDGF:Phospho-PDGF receptor dimer:Grb2:Sos1 [plasma membrane] (Homo sapiens)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Homo sapiens)
Phospho- PDGF receptor dimer [plasma membrane] (Homo sapiens)
Phospho-alpha receptor homodimer [plasma membrane] (Homo sapiens)
STAT binds to the active receptor (Homo sapiens)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Homo sapiens)
Phospho- PDGF receptor dimer [plasma membrane] (Homo sapiens)
Phospho-alpha receptor homodimer [plasma membrane] (Homo sapiens)
PDGF:phospho-PDGF receptor dimer:STAT [plasma membrane] (Homo sapiens)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Homo sapiens)
Phospho- PDGF receptor dimer [plasma membrane] (Homo sapiens)
Phospho-alpha receptor homodimer [plasma membrane] (Homo sapiens)
p130Cas and C3G bind PDGFR bound Crk (Homo sapiens)
PDGF:Phospho-PDGF receptor dimer:Crk [plasma membrane] (Homo sapiens)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Homo sapiens)
Phospho- PDGF receptor dimer [plasma membrane] (Homo sapiens)
Phospho-alpha receptor homodimer [plasma membrane] (Homo sapiens)
PDGF:Phospho-PDGF receptor dimer:Crk:p130Cas:C3G [plasma membrane] (Homo sapiens)
PDGF:Phospho-PDGF receptor dimer:Crk [plasma membrane] (Homo sapiens)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Homo sapiens)
Phospho- PDGF receptor dimer [plasma membrane] (Homo sapiens)
Phospho-alpha receptor homodimer [plasma membrane] (Homo sapiens)
Participants
components
x 2
p-11Y-PDGFRA [plasma membrane]
(Homo sapiens)
Participates
as a component of
Phospho PDGF alpha receptor:PDGF dimers [plasma membrane] (Homo sapiens)
as a member of
Phospho- PDGF receptor dimer [plasma membrane] (Homo sapiens)
Inferred To
Phospho-alpha receptor homodimer [plasma membrane]
(Bos taurus)
Phospho-alpha receptor homodimer [plasma membrane]
(Caenorhabditis elegans)
Phospho-alpha receptor homodimer [plasma membrane]
(Canis familiaris)
Phospho-alpha receptor homodimer [plasma membrane]
(Danio rerio)
Phospho-alpha receptor homodimer [plasma membrane]
(Drosophila melanogaster)
Phospho-alpha receptor homodimer [plasma membrane]
(Gallus gallus)
Phospho-alpha receptor homodimer [plasma membrane]
(Mus musculus)
Phospho-alpha receptor homodimer [plasma membrane]
(Rattus norvegicus)
Phospho-alpha receptor homodimer [plasma membrane]
(Sus scrofa)
Phospho-alpha receptor homodimer [plasma membrane]
(Xenopus tropicalis)
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