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NEUROG3 [nucleoplasm]
Stable Identifier
R-HSA-189530
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
NGN3
Icon
Locations in the PathwayBrowser for interactor UniProt:Q96TC7 RMD3
Expand all
Developmental Biology (Homo sapiens)
Regulation of beta-cell development (Homo sapiens)
Regulation of gene expression in endocrine-committed (NEUROG3+) progenitor cells (Homo sapiens)
NEUROG3-dependent synthesis of INSM1 (Homo sapiens)
NEUROG3 [nucleoplasm] (Homo sapiens)
NEUROG3-dependent synthesis of NEUROD1 (Homo sapiens)
NEUROG3 [nucleoplasm] (Homo sapiens)
NEUROG3-dependent synthesis of NKX2-2 (Homo sapiens)
NEUROG3 [nucleoplasm] (Homo sapiens)
NEUROG3-dependent synthesis of PAX4 protein (Homo sapiens)
NEUROG3 [nucleoplasm] (Homo sapiens)
Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells (Homo sapiens)
HNF6-dependent synthesis of NEUROG3 protein during morphogenesis (Homo sapiens)
NEUROG3 [nucleoplasm] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q9Y4Z2 NEUROG3
Gene Names
NEUROG3, ATOH5, BHLHA7, NGN3
Chain
chain:1-214
Reference Genes
BioGPS Gene:50674 NEUROG3
COSMIC (genes):NEUROG3 NEUROG3
CTD Gene:50674 NEUROG3
dbSNP Gene:50674 NEUROG3
ENSEMBL:ENSG00000122859 NEUROG3
HGNC:13806 NEUROG3
Monarch:50674 NEUROG3
NCBI Gene:50674 NEUROG3
OMIM:604882 NEUROG3
UCSC:Q9Y4Z2 NEUROG3
Reference Transcript
RefSeq:XM_017016280.1 NEUROG3
RefSeq:NM_020999.3 NEUROG3
Other Identifiers
11738385_at
16715079
207965_PM_at
207965_at
31658_at
3293015
3293016
3293019
3293020
50674
7934083
A_23_P35534
A_33_P3292844
GO:0000122
GO:0000785
GO:0000978
GO:0000981
GO:0001227
GO:0001228
GO:0003677
GO:0003690
GO:0003700
GO:0005515
GO:0005634
GO:0006355
GO:0007399
GO:0007417
GO:0007422
GO:0007423
GO:0021510
GO:0030154
GO:0030855
GO:0030900
GO:0030902
GO:0031490
GO:0043226
GO:0045597
GO:0045666
GO:0045893
GO:0045944
GO:0046983
GO:0048814
GO:0048856
GO:0060290
GO:0061564
GO:0070888
GO:0140110
GO:1990837
HMNXSV003004995
ILMN_1765244
PH_hs_0012624
TC10001357.hg
g10337610_3p_at
Participates
as an output of
HNF6-dependent synthesis of NEUROG3 protein during morphogenesis (Homo sapiens)
This entity regulates
Positively
NEUROG3-dependent synthesis of NEUROD1
(Homo sapiens)
NEUROG3-dependent synthesis of NKX2-2
(Homo sapiens)
NEUROG3-dependent synthesis of PAX4 protein
(Homo sapiens)
NEUROG3-dependent synthesis of INSM1
(Homo sapiens)
Cross References
OpenTargets
ENSG00000122859
ENSEMBL
ENSP00000242462
,
ENST00000242462
HPA
ENSG00000122859-NEUROG3
PRO
Q9Y4Z2
Pharos - Targets
Q9Y4Z2
Orphanet
NEUROG3
Interactors (28)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q99081-3 TCF12
0.782
7
UniProt:Q99081 TCF12
1
TCF12 [nucleoplasm]
(R-HSA-445670)
0.743
6
UniProt:P15884-3 TCF4
0.601
4
UniProt:P78424 PO6F2
0.556
3
UniProt:Q04864 REL
2
REL [cytosol]
(R-HSA-1168579)
REL [nucleoplasm]
(R-HSA-1168585)
0.556
3
UniProt:A0PJZ3 GXYLT2
1
GXYLT2 [plasma membrane]
(R-HSA-9926322)
0.527
2
UniProt:Q9H5Z1 DHX35
1
DHX35 [nucleoplasm]
(R-HSA-9770427)
0.527
2
UniProt:P47928 ID4
1
ID4 [nucleoplasm]
(R-HSA-3701048)
0.527
2
UniProt:O95631 NTN1
1
NTN1 [extracellular region]
(R-HSA-373624)
0.527
2
UniProt:P56182 RRP1
1
RRP1 [nucleoplasm]
(R-HSA-6792441)
0.527
2
UniProt:Q96LZ7 RMD2
0.527
2
UniProt:Q96TC7 RMD3
0.527
2
UniProt:Q8NAF0 ZN579
0.527
2
UniProt:O00567 NOP56
2
NOP56 [nucleoplasm]
(R-HSA-6790696)
NOP56 [cytosol]
(R-HSA-391293)
0.527
2
UniProt:O94761 RECQ4
0.527
3
UniProt:O00488 ZN593
0.527
2
UniProt:P15884 TCF4
1
TCF4 [nucleoplasm]
(R-HSA-445672)
0.527
2
UniProt:Q6P158 DHX57
0.527
2
UniProt:Q8IYN0 ZNF100
1
ZNF100 [nucleoplasm]
(R-HSA-975035)
0.527
2
UniProt:Q8IZT6 ASPM
0.527
2
UniProt:Q15751 HERC1
1
HERC1 [cytosol]
(R-HSA-8851655)
0.527
3
UniProt:Q9NXF1 TEX10
1
TEX10 [nucleoplasm]
(R-HSA-3826589)
0.527
2
UniProt:Q07021 C1QBP
3
C1QBP [plasma membrane]
(R-HSA-158123)
C1QBP [mitochondrial matrix]
(R-HSA-9645697)
C1QBP [cytosol]
(R-HSA-9645690)
0.527
3
UniProt:Q14966 ZNF638
1
ZNF638 [nucleoplasm]
(R-HSA-8939429)
0.527
3
UniProt:P22087 FBL
1
FBL [nucleoplasm]
(R-HSA-6790638)
0.527
3
UniProt:Q9H8G1 ZNF430
1
ZNF430 [nucleoplasm]
(R-HSA-1247517)
0.527
2
UniProt:Q8N9Z2 CC71L
0.527
2
UniProt:Q8WV16 DCAF4
1
DCAF4 [nucleoplasm]
(R-HSA-8955191)
0.527
3
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