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Activated TrkA receptor complex [endosome membrane]
Stable Identifier
R-HSA-190083
Type
Complex
Species
Homo sapiens
Compartment
endosome membrane
Locations in the PathwayBrowser
Expand all
Signal Transduction (Homo sapiens)
Signaling by Receptor Tyrosine Kinases (Homo sapiens)
Signaling by NTRKs (Homo sapiens)
Signaling by NTRK1 (TRKA) (Homo sapiens)
Activation of TRKA receptors (Homo sapiens)
TRKA activation by NGF (Homo sapiens)
Activated TrkA receptor internalizes to endosomes (Homo sapiens)
Activated TrkA receptor complex [endosome membrane] (Homo sapiens)
Signalling to ERKs (Homo sapiens)
Prolonged ERK activation events (Homo sapiens)
Frs2-mediated activation (Homo sapiens)
(Frs2)C3G stimulates nucleotide exchange on Rap1 (Homo sapiens)
Active TrkA receptor:p-FRS2:CRKL:RAPGEF1 [endosome membrane] (Homo sapiens)
Active TrkA receptor:p-FRS2:CRKL complex [endosome membrane] (Homo sapiens)
Activated TrkA receptor complex [endosome membrane] (Homo sapiens)
FRS2 binds to active TrkA receptor (Homo sapiens)
Activated TrkA receptor complex [endosome membrane] (Homo sapiens)
Active TrkA receptor:FRS2 complex [endosome membrane] (Homo sapiens)
Activated TrkA receptor complex [endosome membrane] (Homo sapiens)
FRS2 is phosphorylated by active TrkA receptor (Homo sapiens)
Active TrkA receptor:FRS2 complex [endosome membrane] (Homo sapiens)
Activated TrkA receptor complex [endosome membrane] (Homo sapiens)
Active TrkA receptor:p-FRS2 complex [endosome membrane] (Homo sapiens)
Activated TrkA receptor complex [endosome membrane] (Homo sapiens)
p-FRS2 binds CRKL (Homo sapiens)
Active TrkA receptor:p-FRS2 complex [endosome membrane] (Homo sapiens)
Activated TrkA receptor complex [endosome membrane] (Homo sapiens)
Active TrkA receptor:p-FRS2:CRKL complex [endosome membrane] (Homo sapiens)
Activated TrkA receptor complex [endosome membrane] (Homo sapiens)
p-FRS2:CRKL binds C3G (Homo sapiens)
Active TrkA receptor:p-FRS2:CRKL complex [endosome membrane] (Homo sapiens)
Activated TrkA receptor complex [endosome membrane] (Homo sapiens)
Active TrkA receptor:p-FRS2:CRKL:RAPGEF1 [endosome membrane] (Homo sapiens)
Active TrkA receptor:p-FRS2:CRKL complex [endosome membrane] (Homo sapiens)
Activated TrkA receptor complex [endosome membrane] (Homo sapiens)
Participants
components
beta-NGF homodimer [cytosol]
(Homo sapiens)
x 2
p-5Y-NTRK1-1 [endosome membrane]
(Homo sapiens)
Participates
as an output of
Activated TrkA receptor internalizes to endosomes (Homo sapiens)
as an input of
FRS2 binds to active TrkA receptor (Homo sapiens)
as a component of
Active TrkA receptor:FRS2 complex [endosome membrane] (Homo sapiens)
Active TrkA receptor:p-FRS2 complex [endosome membrane] (Homo sapiens)
Active TrkA receptor:p-FRS2:CRKL complex [endosome membrane] (Homo sapiens)
Inferred To
Activated TrkA receptor complex [endosome membrane]
(Bos taurus)
Activated TrkA receptor complex [endosome membrane]
(Canis familiaris)
Activated TrkA receptor complex [endosome membrane]
(Gallus gallus)
Activated TrkA receptor complex [endosome membrane]
(Mus musculus)
Activated TrkA receptor complex [endosome membrane]
(Rattus norvegicus)
Activated TrkA receptor complex [endosome membrane]
(Sus scrofa)
Activated TrkA receptor complex [endosome membrane]
(Xenopus tropicalis)
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