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FGFR1c homodimer [plasma membrane]
Stable Identifier
R-HSA-190222
Type
Complex
Species
Homo sapiens
Compartment
plasma membrane
Locations in the PathwayBrowser
Expand all
Developmental Biology (Homo sapiens)
Nervous system development (Homo sapiens)
Axon guidance (Homo sapiens)
NCAM signaling for neurite out-growth (Homo sapiens)
NCAM1 binds FGFR-1 (Homo sapiens)
FGFR1c homodimer [plasma membrane] (Homo sapiens)
NCAM1:FGFR-1 [plasma membrane] (Homo sapiens)
FGFR1c homodimer [plasma membrane] (Homo sapiens)
Disease (Homo sapiens)
Diseases of signal transduction by growth factor receptors and second messengers (Homo sapiens)
Signaling by FGFR in disease (Homo sapiens)
Signaling by FGFR1 in disease (Homo sapiens)
FGFR1 mutant receptor activation (Homo sapiens)
Signaling by FGFR1 amplification mutants (Homo sapiens)
Ligand-independent dimerization of overexpressed FGFR1c (Homo sapiens)
FGFR1c homodimer [plasma membrane] (Homo sapiens)
Ligand-independent phosphorylation of overexpressed FGFR1c (Homo sapiens)
FGFR1c homodimer [plasma membrane] (Homo sapiens)
Tyrosine kinase inhibitors bind and inhibit overexpressed FGFR1 dimers (Homo sapiens)
Overexpressed FGFR1 homodimers [plasma membrane] (Homo sapiens)
FGFR1c homodimer [plasma membrane] (Homo sapiens)
Overexpressed FGFR1:TKIs [plasma membrane] (Homo sapiens)
Overexpressed FGFR1 homodimers [plasma membrane] (Homo sapiens)
FGFR1c homodimer [plasma membrane] (Homo sapiens)
Signal Transduction (Homo sapiens)
Signaling by Receptor Tyrosine Kinases (Homo sapiens)
Signaling by FGFR (Homo sapiens)
Signaling by FGFR1 (Homo sapiens)
FGFR1 ligand binding and activation (Homo sapiens)
FGFR1c and Klotho ligand binding and activation (Homo sapiens)
Autocatalytic phosphorylation of Klotho-bound FGFR1c (Homo sapiens)
FGF23 bound to Klotho and FGFR1c [plasma membrane] (Homo sapiens)
FGFR1c homodimer [plasma membrane] (Homo sapiens)
FGFR1c binds to Klotho-bound FGF23 (Homo sapiens)
FGF23 bound to Klotho and FGFR1c [plasma membrane] (Homo sapiens)
FGFR1c homodimer [plasma membrane] (Homo sapiens)
FGFR1c ligand binding and activation (Homo sapiens)
Autocatalytic phosphorylation of FGFR1c (Homo sapiens)
FGFR1c homodimer bound to FGF [plasma membrane] (Homo sapiens)
FGFR1c homodimer [plasma membrane] (Homo sapiens)
FGFR1c binds to FGF (Homo sapiens)
FGFR1c homodimer bound to FGF [plasma membrane] (Homo sapiens)
FGFR1c homodimer [plasma membrane] (Homo sapiens)
Participants
components
x 2
FGFR1c [plasma membrane]
(Homo sapiens)
Participates
as a member of
Overexpressed FGFR1 homodimers [plasma membrane] (Homo sapiens)
as an input of
Ligand-independent phosphorylation of overexpressed FGFR1c (Homo sapiens)
NCAM1 binds FGFR-1 (Homo sapiens)
as an output of
Ligand-independent dimerization of overexpressed FGFR1c (Homo sapiens)
as a component of
NCAM1:FGFR-1 [plasma membrane] (Homo sapiens)
FGFR1c homodimer bound to FGF [plasma membrane] (Homo sapiens)
FGF23 bound to Klotho and FGFR1c [plasma membrane] (Homo sapiens)
Inferred To
FGFR-1 homodimer [plasma membrane]
(Mus musculus)
FGFR1c homodimer [plasma membrane]
(Bos taurus)
FGFR1c homodimer [plasma membrane]
(Caenorhabditis elegans)
FGFR1c homodimer [plasma membrane]
(Canis familiaris)
FGFR1c homodimer [plasma membrane]
(Danio rerio)
FGFR1c homodimer [plasma membrane]
(Drosophila melanogaster)
FGFR1c homodimer [plasma membrane]
(Gallus gallus)
FGFR1c homodimer [plasma membrane]
(Rattus norvegicus)
FGFR1c homodimer [plasma membrane]
(Sus scrofa)
FGFR1c homodimer [plasma membrane]
(Xenopus tropicalis)
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