Mevalonate is phosphorylated to mevalonate-5-phosphate

Stable Identifier
R-HSA-191380
Type
Reaction [transition]
Species
Homo sapiens
Compartment
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Mevalonate kinase (MK) catalyzes the phosphorylation of mevalonate to mevalonate-5-phosphate.

Literature References
PubMed ID Title Journal Year
1377680 Molecular cloning of human mevalonate kinase and identification of a missense mutation in the genetic disease mevalonic aciduria

Mosley, ST, Bishop, RW, Schafer, BL, Kalinowski, SS, Kratunis, VJ, Gibson, KM, Tanaka, RD

J Biol Chem 1992
14730012 Mevalonate kinase is a cytosolic enzyme in humans

Koster, J, Tuyp, JJ, Wanders, RJ, Espeel, M, Waterham, HR, Hogenboom, S

J Cell Sci 2004
Participants
Participates
Catalyst Activity

mevalonate kinase activity of MVK dimer [cytosol]

Orthologous Events
Cross References
Rhea
Authored
Reviewed
Created
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