Reactome | SNRPG [cytosol]

SNRPG [cytosol]

Stable Identifier

R-HSA-191827

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

Sm protein G, snRNP G, RUXG_HUMAN, Small nuclear ribonucleoprotein G, snRNP-G, Sm-G, SmG

Locations in the PathwayBrowser

Expand all

Disease (Homo sapiens)

- Infectious disease (Homo sapiens)
  - SARS-CoV Infections (Homo sapiens)
    - SARS-CoV-2 Infection (Homo sapiens)
      - SARS-CoV-2-host interactions (Homo sapiens)
        
        SARS-CoV-2 modulates host translation machinery (Homo sapiens)
        
        snRNP complex assembly (Homo sapiens)
        
        SMN:SM protein complex [cytosol] (Homo sapiens)
        
        snRNP Sm core complex [cytosol] (Homo sapiens)
        
        SNRPG [cytosol] (Homo sapiens)
        
        Spliceosomal m7G capped snRNAs with SMN:SM protein complex bound [cytosol] (Homo sapiens)
        
        SMN:SM protein complex [cytosol] (Homo sapiens)
        
        snRNP Sm core complex [cytosol] (Homo sapiens)
        
        SNRPG [cytosol] (Homo sapiens)

External Reference Information

External Reference

UniProt:P62308 SNRPG

Gene Names

SNRPG, PBSCG

Chain

chain:1-76

Reference Genes

BioGPS Gene:6637 SNRPG

COSMIC (genes):SNRPG SNRPG

CTD Gene:6637 SNRPG

dbSNP Gene:6637 SNRPG

ENSEMBL:ENSG00000143977 SNRPG

HGNC:11163 SNRPG

KEGG Gene (Homo sapiens):6637 SNRPG

Monarch:6637 SNRPG

NCBI Gene:6637 SNRPG

OMIM:603542 SNRPG

UCSC:P62308 SNRPG

Reference Transcript

RefSeq:NM_003096.3 SNRPG

Other Identifiers

0004730242

11753974_s_at

11757703_x_at

205644_s_at

2558579

2558580

2558581

2558585

2558586

2558592

2558593

2558594

37337_at

3808680

3822797

6637

8026339

A_23_P102235

GE81234

GO:0000245

GO:0000387

GO:0000398

GO:0003674

GO:0003723

GO:0005515

GO:0005575

GO:0005622

GO:0005634

GO:0005654

GO:0005681

GO:0005682

GO:0005683

GO:0005685

GO:0005686

GO:0005687

GO:0005689

GO:0005737

GO:0005829

GO:0006369

GO:0006397

GO:0006810

GO:0006913

GO:0008150

GO:0008334

GO:0008380

GO:0009058

GO:0022607

GO:0022618

GO:0030532

GO:0032991

GO:0034641

GO:0034709

GO:0034719

GO:0043186

GO:0043226

GO:0046540

GO:0051170

GO:0065003

GO:0071004

GO:0071005

GO:0071007

GO:0071011

GO:0071013

GO:0097526

GO:1990446

GO:1990904

HMNXSV003000227

ILMN_1683562

PH_hs_0030244

X85373_at

g4507132_3p_a_at

Participates

as an input of

Loading and methylation of Sm proteins onto SMN Complexes (Homo sapiens)

as a component of

snRNP Sm core complex [cytosol] (Homo sapiens)

Other forms of this molecule

SNRPG [nucleoplasm]

Inferred To

SMX2 [cytosol] (Saccharomyces cerevisiae)

snr-7 [cytosol] (Caenorhabditis elegans)

Snrpg [cytosol] (Mus musculus)

Snrpg [cytosol] (Rattus norvegicus)

snrpg [cytosol] (Danio rerio)

snrpg [cytosol] (Xenopus tropicalis)

smg1 [cytosol] (Schizosaccharomyces pombe)

SNRPG [cytosol] (Bos taurus)

SNRPG [cytosol] (Canis familiaris)

SNRPG [cytosol] (Drosophila melanogaster)

SNRPG [cytosol] (Plasmodium falciparum)

SNRPG [cytosol] (Sus scrofa)

SNRPGP15 [cytosol] (Gallus gallus)

snrpG [cytosol] (Dictyostelium discoideum)

Cross References

RefSeq

NP_003087.1

OpenTargets

ENSG00000143977

HPA

ENSG00000143977-SNRPG

GeneCards

P62308

Ensembl

ENST00000272348, ENSG00000143977, ENSP00000272348

PRO

P62308

Pharos - Targets

P62308

PDB

5Z56, 6Y53, 6V4X, 4F7U, 7B0Y, 5Z57, 5Z58, 4V98, 5O9Z, 6QW6, 5XJC, 5YZG, 7A5P, 5XJR, 5XJT, 6Y5Q, 3JCR, 6AH0, 5XJL, 5MQF, 5XJQ, 4WZJ, 6QDV, 6QX9, 7ABI, 6ICZ, 3CW1, 5XJU, 4PJO, 6FF7, 7ABG, 6ID0, 6ID1, 6AHD, 7DVQ, 3PGW

Interactors (14)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q96D03 DDT4L			0.857	13
UniProt:P62304 SNRPE	2	SNRPE [nucleoplasm] (R-HSA-71905) SNRPE [cytosol] (R-HSA-191782)	0.829	8
UniProt:P54105 CLNS1A	1	CLNS1A [cytosol] (R-HSA-191796)	0.799	9
UniProt:Q16637 SMN1	2	SMN1 [nucleoplasm] (R-HSA-191892) SMN1 [cytosol] (R-HSA-191839)	0.734	4
UniProt:O75410-1 TACC1			0.72	5
UniProt:Q13643 FHL3			0.718	6
UniProt:P14678 SNRPB	4	Me2-R108,R112-SNRPB [nucleoplasm] (R-HSA-192213) SNRPB [nucleoplasm] (R-HSA-71896) SNRPB [cytosol] (R-HSA-191798) 2xMe-SNRPB [cytosol] (R-HSA-192218)	0.656	3
UniProt:O14893 GEMIN2	2	GEMIN2 [nucleoplasm] (R-HSA-191795) GEMIN2 [cytosol] (R-HSA-191835)	0.623	4
UniProt:Q8NCF5-2 NFATC2IP			0.556	3
UniProt:Q03403 TFF2			0.556	3
UniProt:O95988 TCL1B			0.556	3
UniProt:Q06547-3 GABPB1	1	NRF2 gamma-1 subunit [nucleoplasm] (R-HSA-1592216)	0.556	3
UniProt:Q8WWY3 PRPF31	1	PRPF31 [nucleoplasm] (R-HSA-6806772)	0.508	2
UniProt:P14678-2 SNRPB			0.499	2