Reactome | SNRPF [cytosol]

SNRPF [cytosol]

Stable Identifier

R-HSA-191852

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

Sm protein F, snRNP F, RUXF_HUMAN, Small nuclear ribonucleoprotein F, snRNP-F, Sm-F, SmF

Locations in the PathwayBrowser for interactor UniProt:Q96GM8 TOE1

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External Reference Information

External Reference

UniProt:P62306 SNRPF

Gene Names

SNRPF, PBSCF

Chain

initiator methionine:, chain:2-86

Reference Genes

BioGPS Gene:6636 SNRPF

COSMIC (genes):SNRPF SNRPF

CTD Gene:6636 SNRPF

dbSNP Gene:6636 SNRPF

ENSEMBL:ENSG00000139343 SNRPF

ENSEMBL_homo_sapiens_GENE:ENSG00000139343.11 SNRPF

HGNC:11162 SNRPF

KEGG Gene (Homo sapiens):6636 SNRPF

Monarch:6636 SNRPF

NCBI Gene:6636 SNRPF

OMIM:603541 SNRPF

UCSC:P62306 SNRPF

Reference Transcript

RefSeq:NM_003095.2 SNRPF

Other Identifiers

11717013_a_at

11717014_x_at

11753840_x_at

11763977_x_at

203832_PM_at

203832_at

3427016

3427017

3427018

3427019

3427021

3427023

3427024

3909005

3909010

41403_at

6636

7957649

A_23_P117068

A_24_P504405

GE60100

GO:0000387

GO:0000398

GO:0003723

GO:0005515

GO:0005634

GO:0005654

GO:0005681

GO:0005682

GO:0005683

GO:0005684

GO:0005685

GO:0005686

GO:0005687

GO:0005689

GO:0005737

GO:0005829

GO:0006397

GO:0008380

GO:0016071

GO:0030532

GO:0034709

GO:0034715

GO:0034719

GO:0036261

GO:0043226

GO:0043229

GO:0046540

GO:0065003

GO:0071005

GO:0071007

GO:0071013

GO:0120114

GO:1903241

GO:1990904

HMNXSV003050943

ILMN_2067370

X85372_at

g4507130_3p_at

g4507130_3p_x_at

Participates

as an input of

Loading and methylation of Sm proteins onto SMN Complexes (Homo sapiens)

as a component of

snRNP Sm core complex [cytosol] (Homo sapiens)

Other forms of this molecule

SNRPF [nucleoplasm]

Inferred To

Homologues of SNRPF [cytosol] (Canis familiaris)

SMX3 [cytosol] (Saccharomyces cerevisiae)

SNRPF [cytosol] (Bos taurus)

SNRPF [cytosol] (Canis familiaris)

SNRPF [cytosol] (Gallus gallus)

SNRPF [cytosol] (Plasmodium falciparum)

SNRPF [cytosol] (Sus scrofa)

SmF [cytosol] (Drosophila melanogaster)

Snrpf [cytosol] (Mus musculus)

Snrpf [cytosol] (Rattus norvegicus)

smf1 [cytosol] (Schizosaccharomyces pombe)

snrpf [cytosol] (Danio rerio)

snrpf [cytosol] (Dictyostelium discoideum)

snrpf [cytosol] (Xenopus tropicalis)

snr-5 [cytosol] (Caenorhabditis elegans)

Cross References

RefSeq

NP_003086.1

OpenTargets

ENSG00000139343

HPA

ENSG00000139343-SNRPF

GeneCards

P62306

Ensembl

ENSG00000139343, ENST00000266735, ENSP00000266735

PRO

P62306

Pharos - Targets

P62306

PDB

7VPX, 8Y6O, 8Q7V, 5XJU, 7W5B, 7A5P, 6QX9, 5XJT, 7QTT, 7W5A, 5Z56, 8RC0, 5YZG, 5XJQ, 3PGW, 8Y7E, 4PJO, 6ID0, 8QO9, 3CW1, 7EVO, 5XJC, 8Q7X, 6V4X, 6AH0, 4F7U, 5Z58, 5XJS, 7B0Y, 8Q7Q, 4V98, 5XJR, 8C6J, 8HK1, 6ID1, 8Q91, 6ICZ, 7W59, 5Z57, 6Y5Q, 5XJL, 6QDV, 5MQF, 6FF7, 7ABI, 6QW6, 8CH6, 7DVQ, 4WZJ, 7ABG, 5O9Z, 3JCR, 6Y53, 8Q7W

Interactors (104)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P62304 SNRPE	2	SNRPE [nucleoplasm] (R-HSA-71905) SNRPE [cytosol] (R-HSA-191782)	0.93	14
UniProt:P62316 SNRPD2	2	SNRPD2 [nucleoplasm] (R-HSA-71901) SNRPD2 [cytosol] (R-HSA-191810)	0.885	15
UniProt:Q9Y4Y9 LSM5	2	LSM5 [cytosol] (R-HSA-429839) LSM5 [nucleoplasm] (R-HSA-6806795)	0.879	13
UniProt:O14893 GEMIN2	2	GEMIN2 [nucleoplasm] (R-HSA-191795) GEMIN2 [cytosol] (R-HSA-191835)	0.873	14
UniProt:P54105 CLNS1A	1	CLNS1A [cytosol] (R-HSA-191796)	0.829	9
UniProt:P14678 SNRPB	4	SNRPB [nucleoplasm] (R-HSA-71896) Me2-R108,R112-SNRPB [nucleoplasm] (R-HSA-192213) SNRPB [cytosol] (R-HSA-191798) 2xMe-SNRPB [cytosol] (R-HSA-192218)	0.793	7
UniProt:Q16637 SMN1	2	SMN1 [nucleoplasm] (R-HSA-191892) SMN1 [cytosol] (R-HSA-191839)	0.788	7
UniProt:P38432 COIL			0.782	7
UniProt:Q8WXD5 GEMIN6	2	GEMIN6 [nucleoplasm] (R-HSA-191799) GEMIN6 [cytosol] (R-HSA-191771)	0.759	5
UniProt:Q15428 SF3A2	1	SF3A2 [nucleoplasm] (R-HSA-71964)	0.744	6
UniProt:O95400 CD2BP2	1	CD2BP2 [nucleoplasm] (R-HSA-72054)	0.744	6
UniProt:Q9UK45 LSM7	2	LSM7 [nucleoplasm] (R-HSA-6806802) LSM7 [cytosol] (R-HSA-2028610)	0.743	7
UniProt:P09661 SNRPA1	1	SNRPA1 [nucleoplasm] (R-HSA-71958)	0.738	5
UniProt:O60306 AQR	1	AQR [nucleoplasm] (R-HSA-6781960)	0.731	5
UniProt:P08621 SNRNP70	1	SNRNP70 [nucleoplasm] (R-HSA-71913)	0.725	7
UniProt:Q9NSC5 HOMER3	1	HOMER3 [cytosol] (R-HSA-6794236)	0.718	9
UniProt:P62310 LSM3	2	LSM3 [nucleoplasm] (R-HSA-6806807) LSM3 [cytosol] (R-HSA-429894)	0.666	4
UniProt:P62312 LSM6	2	LSM6 [cytosol] (R-HSA-429936) LSM6 [nucleoplasm] (R-HSA-6806794)	0.659	3
UniProt:P83369 LSM11	1	LSM11 [nucleoplasm] (R-HSA-110760)	0.643	4
UniProt:Q96LT9 RNPC3	1	RNPC3 [nucleoplasm] (R-HSA-6787844)	0.643	4
UniProt:Q8TEQ6 GEMIN5	2	GEMIN5 [cytosol] (R-HSA-191833) GEMIN5 [nucleoplasm] (R-HSA-191765)	0.643	4
UniProt:P08579 SNRPB2	1	SNRPB2 [nucleoplasm] (R-HSA-71960)	0.643	5
UniProt:O60508 CDC40	1	CDC40 [nucleoplasm] (R-HSA-72062)	0.643	4
UniProt:Q9UHI6 DDX20	2	DDX20 [nucleoplasm] (R-HSA-191847) DDX20 [cytosol] (R-HSA-191838)	0.643	4
UniProt:Q9Y333 LSM2	2	LSM2 [nucleoplasm] (R-HSA-71894) LSM2 [cytosol] (R-HSA-429849)	0.643	3
UniProt:Q15020 SART3			0.643	4
UniProt:Q9BWU0 NADAP			0.643	3
UniProt:Q9UBB9 TFIP11	1	TFIP11 [nucleoplasm] (R-HSA-8869310)	0.643	4
UniProt:Q6P2Q9 PRPF8	1	PRPF8 [nucleoplasm] (R-HSA-83810)	0.643	5
UniProt:Q9HCS7 XAB2	1	XAB2 [nucleoplasm] (R-HSA-67411)	0.643	4
UniProt:Q9NWZ8 GEMIN8	2	GEMIN8 [nucleoplasm] (R-HSA-8932892) GEMIN8 [cytosol] (R-HSA-8932878)	0.643	4
UniProt:O15116 LSM1	1	LSM1 [cytosol] (R-HSA-429976)	0.643	3
UniProt:Q9BUQ8 DDX23	1	DDX23 [nucleoplasm] (R-HSA-71879)	0.643	4
UniProt:O94906 PRPF6	1	PRPF6 [nucleoplasm] (R-HSA-71881)	0.643	4
UniProt:Q15427 SF3B4	1	SF3B4 [nucleoplasm] (R-HSA-71975)	0.643	4
UniProt:Q15029 EFTUD2	1	EFTUD2 [nucleoplasm] (R-HSA-71883)	0.643	5
UniProt:P09234 SNRPC	1	SNRPC [nucleoplasm] (R-HSA-8865876)	0.643	5
UniProt:P57678 GEMIN4	2	GEMIN4 [nucleoplasm] (R-HSA-191841) GEMIN4 [cytosol] (R-HSA-191836)	0.643	4
UniProt:O75533 SF3B1	1	SF3B1 [nucleoplasm] (R-HSA-71968)	0.643	4
UniProt:Q13573 SNW1	1	SNW1 [nucleoplasm] (R-HSA-351663)	0.643	3
UniProt:Q96DI7 SNRNP40	1	SNRNP40 [nucleoplasm] (R-HSA-71877)	0.643	3
UniProt:O95777 LSM8	1	LSM8 [nucleoplasm] (R-HSA-6806779)	0.643	3
UniProt:P09012 SNRPA	1	SNRPA [nucleoplasm] (R-HSA-71915)	0.643	5
UniProt:Q6IEG0 SNRNP48	1	SNRNP48 [nucleoplasm] (R-HSA-6787849)	0.643	3
UniProt:O43719 HTATSF1	1	HTATSF1 [nucleoplasm] (R-HSA-9770246)	0.643	4
UniProt:Q15696 ZRSR2	1	ZRSR2 [nucleoplasm] (R-HSA-8865914)	0.643	3
UniProt:Q9H6E5 STPAP			0.643	4
UniProt:Q15459 SF3A1	1	SF3A1 [nucleoplasm] (R-HSA-71962)	0.643	5
UniProt:Q8N954 GPT11			0.643	4
UniProt:O43395 PRPF3	1	PRPF3 [nucleoplasm] (R-HSA-6806806)	0.643	4
UniProt:Q8IYT2 CMTR2			0.643	4
UniProt:P62314 SNRPD1	3	2xMe-SNRPD1 [nucleoplasm] (R-HSA-192215) SNRPD1 [cytosol] (R-HSA-191890) 2xMe-SNRPD1 [cytosol] (R-HSA-192217)	0.643	4
UniProt:P83876 TXNL4A	1	TXNL4A [nucleoplasm] (R-HSA-71875)	0.643	4
UniProt:Q9P2G9 KLHL8			0.643	4
UniProt:Q9Y5B6 PAXB1			0.643	3
UniProt:Q96RS0 TGS1	2	TGS1 [cytosol] (R-HSA-192209) TGS1 [nucleoplasm] (R-HSA-400176)	0.643	3
UniProt:Q96GM8 TOE1			0.643	4
UniProt:O75643 SNRNP200	1	SNRNP200 [nucleoplasm] (R-HSA-71885)	0.643	4
UniProt:P62318 SNRPD3	3	SNRPD3 [nucleoplasm] (R-HSA-71903) 2xMe-SNRPD3 [nucleoplasm] (R-HSA-192219) 2xMe-SNRPD3 [cytosol] (R-HSA-191781)	0.643	3
UniProt:Q12874 SF3A3	1	SF3A3 [nucleoplasm] (R-HSA-71966)	0.643	4
UniProt:P14678-2 SNRPB			0.623	3
UniProt:Q13422 IKZF1			0.556	3
UniProt:Q9H1P3 OSBPL2	1	OSBPL2 [cytosol] (R-HSA-8867527)	0.556	3
UniProt:Q8TBB1 LNX1	1	LNX1 [cytosol] (R-HSA-8851641)	0.556	3
UniProt:Q6FHY5 Q6FHY5			0.556	3
UniProt:P32969 RPL9	1	RPL9 [cytosol] (R-HSA-72492)	0.556	3
UniProt:Q13422-7 IKZF1			0.556	3
UniProt:P42858 HTT	1	HTT [nucleoplasm] (R-HSA-9023590)	0.556	3
UniProt:Q9BXP5 SRRT	1	SRRT [nucleoplasm] (R-HSA-6814858)	0.547	2
UniProt:P62308 SNRPG	2	SNRPG [nucleoplasm] (R-HSA-71909) SNRPG [cytosol] (R-HSA-191827)	0.547	3
UniProt:Q9HC44 GPBL1			0.527	2
UniProt:Q9H5Z1 DHX35	1	DHX35 [nucleoplasm] (R-HSA-9770427)	0.527	3
UniProt:O43172 PRPF4	1	PRPF4 [nucleoplasm] (R-HSA-71890)	0.527	3
UniProt:P01037 CYTN			0.527	2
UniProt:P01036 CYTS			0.527	2
UniProt:A8MWD9 RUXGL			0.527	2
UniProt:Q86VM9 ZCH18			0.527	2
UniProt:O75554 WBP4	1	WBP4 [nucleoplasm] (R-HSA-8867895)	0.527	2
UniProt:Q9UDW3 ZMAT5	1	ZMAT5 [nucleoplasm] (R-HSA-6787850)	0.527	2
UniProt:Q9BRR8 GPATCH1	1	GPATCH1 [nucleoplasm] (R-HSA-9770419)	0.527	3
UniProt:P02814 SMR3B			0.527	2
UniProt:Q9BZJ0 CRNKL1	1	CRNKL1 [nucleoplasm] (R-HSA-8867899)	0.527	3
UniProt:P63162 SNRPN	1	Me2-R108,R112-SNRPN [nucleoplasm] (R-HSA-8865931)	0.527	3
UniProt:Q9Y312 AAR2			0.527	2
UniProt:Q13523 PRPF4B	1	PRPF4B [nucleoplasm] (R-HSA-9769525)	0.527	2
UniProt:Q2TBE0 CWF19L2	1	CWF19L2 [nucleoplasm] (R-HSA-9770846)	0.527	2
UniProt:Q9NW64 RBM22	1	RBM22 [nucleoplasm] (R-HSA-5215975)	0.527	2
UniProt:O95149 SNUPN	1	SNUPN [cytosol] (R-HSA-191857)	0.527	2
UniProt:Q9BWJ5 SF3B5	1	SF3B5 [nucleoplasm] (R-HSA-71979)	0.527	3
UniProt:P78362 SRPK2	1	SRPK2 [cytosol] (R-HSA-9729332)	0.527	2
UniProt:Q96DA0 PAUF			0.527	2
UniProt:Q9P0M2 AKA7G			0.527	2
UniProt:Q8WWY3 PRPF31	1	PRPF31 [nucleoplasm] (R-HSA-6806772)	0.527	3
UniProt:Q96I25 RBM17	1	RBM17 [nucleoplasm] (R-HSA-8865891)	0.527	2
UniProt:Q7L2J0 MEPCE			0.527	3
UniProt:Q96DR5 BPIFA2	1	BPIFA2 [extracellular region] (R-HSA-6809279)	0.527	2
UniProt:Q969L4 LSM10	1	LSM10 [nucleoplasm] (R-HSA-58738)	0.527	2
UniProt:Q13435 SF3B2	1	SF3B2 [nucleoplasm] (R-HSA-71971)	0.527	3
UniProt:Q16560 SNRNP35	1	SNRNP35 [nucleoplasm] (R-HSA-6787852)	0.527	2
UniProt:O43290 SART1	1	SART1 [nucleoplasm] (R-HSA-4615999)	0.527	2
UniProt:Q8N8D1 PDCD7	1	PDCD7 [nucleoplasm] (R-HSA-6787851)	0.527	3
UniProt:Q8TBF4 ZCRB1	2	ZCRB1 [cytosol] (R-HSA-9682010) ZCRB1 [nucleoplasm] (R-HSA-6787853)	0.527	3
UniProt:Q9BRX9 WDR83	1	WDR83 [endosome membrane] (R-HSA-5672942)	0.527	3
UniProt:Q4G0J3 LARP7			0.483	2

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