5beta-cholestan-3alpha,7alpha,12alpha,27-tetrol is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-27-al

Stable Identifier
R-HSA-192042
Type
Reaction [transition]
Species
Homo sapiens
Compartment
Synonyms
5beta-cholestan-3alpha,7alpha,12alpha,27-tetrol + NADP+ => 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-27-al + NADPH + H+
ReviewStatus
5/5
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5beta-cholestan-3alpha, 7alpha, 12alpha, 27-tetrol and NADP+ react to form 3alpha, 7alpha, 12alpha-trihydroxy-5beta-cholestan-27-al and NADPH + H+. This oxidation reaction occurs in the mitochondrial matrix, catalyzed by CYP27A1.
Participants
Participates
Catalyst Activity

steroid hydroxylase activity of CYP27A1 [mitochondrial matrix]

Orthologous Events
Authored
Reviewed
Created
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