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AMACR [peroxisomal matrix]
Stable Identifier
R-HSA-192146
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
peroxisomal matrix
Synonyms
Alpha-methylacyl-CoA racemase
Locations in the PathwayBrowser
Expand all
Metabolism (Homo sapiens)
Metabolism of lipids (Homo sapiens)
Fatty acid metabolism (Homo sapiens)
Peroxisomal lipid metabolism (Homo sapiens)
Beta-oxidation of pristanoyl-CoA (Homo sapiens)
Isomerization of (2R)-pristanoyl-CoA to (2S)-pristanoyl-CoA (Homo sapiens)
AMACR [peroxisomal matrix] (Homo sapiens)
Metabolism of steroids (Homo sapiens)
Bile acid and bile salt metabolism (Homo sapiens)
Synthesis of bile acids and bile salts (Homo sapiens)
Synthesis of bile acids and bile salts via 24-hydroxycholesterol (Homo sapiens)
Isomerization of 25(R) TetraHCA-CoA to (24R, 25R) 3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA (Homo sapiens)
AMACR [peroxisomal matrix] (Homo sapiens)
Isomerization of 3,7,24THCA-CoA to (24R, 25R) 3alpha,7alpha,24-trihydroxy-5beta-cholestanoyl-CoA (Homo sapiens)
AMACR [peroxisomal matrix] (Homo sapiens)
Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol (Homo sapiens)
Isomerization of 25(R) DHCA-CoA to 25(S) DHCA-CoA (Homo sapiens)
AMACR [peroxisomal matrix] (Homo sapiens)
Isomerization of 25(R) THCA-CoA to 25(S) THCA-CoA (Homo sapiens)
AMACR [peroxisomal matrix] (Homo sapiens)
Protein localization (Homo sapiens)
Peroxisomal protein import (Homo sapiens)
Cargo of PEX5S,L translocates from the cytosol to the peroxisomal matrix (Homo sapiens)
Cargo proteins containing PTS1 [peroxisomal matrix] (Homo sapiens)
AMACR [peroxisomal matrix] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q9UHK6 AMACR
Gene Names
AMACR
Chain
chain:1-382
Reference Genes
BioGPS Gene:23600 AMACR
COSMIC (genes):AMACR AMACR
CTD Gene:23600 AMACR
dbSNP Gene:23600 AMACR
ENSEMBL:ENSG00000242110 AMACR
ENSEMBL_homo_sapiens_GENE:ENSG00000242110.9 AMACR
HGNC:451 AMACR
KEGG Gene (Homo sapiens):23600 AMACR
Monarch:23600 AMACR
NCBI Gene:23600 AMACR
OMIM:604489 AMACR
UCSC:Q9UHK6 AMACR
Reference Transcript
RefSeq:NM_001167595.1 AMACR
RefSeq:NM_014324.5 AMACR
RefSeq:NM_203382.2 AMACR
Other Identifiers
11733844_a_at
11739985_a_at
11739986_x_at
11747083_a_at
11753458_a_at
11759333_s_at
11759334_x_at
209424_PM_s_at
209424_s_at
209425_PM_at
209425_at
209426_PM_s_at
209426_s_at
23600
236365_PM_at
236365_at
2852737
2852738
2852739
2852740
2852741
2852743
2852744
2852745
2852746
2852747
2852748
2852754
2852755
2852756
2852757
2852759
2852761
2852762
41706_at
56822_at
8111430
83041_at
90077_at
A_24_P106297
A_33_P3259736
A_33_P3313245
GE54400
GE63218
GO:0003824
GO:0005102
GO:0005737
GO:0005739
GO:0005777
GO:0005782
GO:0005829
GO:0005886
GO:0006629
GO:0006631
GO:0006699
GO:0008111
GO:0008206
GO:0016853
GO:0033540
GO:0043226
GO:0043231
GO:0071704
HMNXSV003008134
HMNXSV003024570
HMNXSV003050857
Hs.128749.0.S1_3p_a_at
Hs.128749.0.S3_3p_at
Hs.128749.0.S3_3p_x_at
Hs.49598.0.A1_3p_at
ILMN_1759670
ILMN_1792741
ILMN_2367172
PH_hs_0022141
TC05003422.hg
g4204096_3p_a_at
p33705
Participates
as a member of
Cargo proteins containing PTS1 [peroxisomal matrix] (Homo sapiens)
Other forms of this molecule
AMACR [cytosol]
Inferred To
Amacr [peroxisomal matrix]
(Drosophila melanogaster)
AMACR [peroxisomal matrix]
(Bos taurus)
AMACR [peroxisomal matrix]
(Caenorhabditis elegans)
AMACR [peroxisomal matrix]
(Gallus gallus)
AMACR [peroxisomal matrix]
(Mus musculus)
AMACR [peroxisomal matrix]
(Rattus norvegicus)
amacr [peroxisomal matrix]
(Danio rerio)
amacr [peroxisomal matrix]
(Xenopus tropicalis)
Cross References
RefSeq
NP_001161067.1
,
NP_055139.4
,
NP_976316.1
OpenTargets
ENSG00000242110
IntEnz
5.1.99.4
GeneCards
Q9UHK6
HPA
ENSG00000242110-AMACR
Ensembl
ENST00000506639
,
ENST00000335606
,
ENSP00000334424
,
ENST00000382072
,
ENSP00000427227
,
ENSP00000371504
,
ENSG00000242110
,
ENSP00000371517
,
ENST00000382085
PRO
Q9UHK6
Pharos - Targets
Q9UHK6
Orphanet
17373
HMDB Protein
HMDBP02680
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