Axonal growth inhibition (RHOA activation)

Stable Identifier
R-HSA-193634
Type
Pathway
Species
Homo sapiens
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Axonal growth inhibition (RHOA activation)
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p75NTR can also form a receptor complex with the Nogo receptor (NgR). Such complexes mediates axonal outgrowth inhibitory signals of MDGIs (myelin-derived growth-inhibitors), such as Nogo66, myelin-associated glycoprotein (MAG), and oligodendrocyte myelin glycoprotein (OMGP).

Literature References
PubMed ID Title Journal Year
12951563 Myelin-associated inhibitors of axonal regeneration in the adult mammalian CNS

Filbin, MT

Nat Rev Neurosci 2003
Participants
Events
Participates
as an event of
Event Information
Go Biological Process
negative regulation of axonogenesis (0050771)
Orthologous Events
Axonal growth inhibition (RHOA activation) (Bos taurus)
Axonal growth inhibition (RHOA activation) (Canis familiaris)
Axonal growth inhibition (RHOA activation) (Danio rerio)
Axonal growth inhibition (RHOA activation) (Drosophila melanogaster)
Axonal growth inhibition (RHOA activation) (Gallus gallus)
Axonal growth inhibition (RHOA activation) (Mus musculus)
Axonal growth inhibition (RHOA activation) (Rattus norvegicus)
Axonal growth inhibition (RHOA activation) (Sus scrofa)
Axonal growth inhibition (RHOA activation) (Xenopus tropicalis)
Cross References
GlyCosmos
Authored
Nasi, S  (2006-10-10)
Annibali, D  (2006-10-10)
Reviewed
Friedman, WJ  (2008-05-20)
Chao, MV  (2008-05-28)
Created
Jassal, B  (2007-02-23)
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