3alpha,7alpha,24(S)-trihydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestanoate (3,7,24THCA)

Stable Identifier
R-HSA-193737
Type
Reaction [transition]
Species
Homo sapiens
Compartment
Synonyms
3alpha,7alpha,24(S)-trihydroxy-5beta-cholestan-27-al + NADPH + H+ + O2 => 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestanoate (3,7,24THCA) + NADP+ + H2O
ReviewStatus
5/5
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3alpha,7alpha,24(S)-trihydroxy-5beta-cholestan-27-al, NADPH + H+, and O2 react to form 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestanoate (3,7,24THCA), NADP+, and H2O. This oxidation reaction occurs in the mitochondrial matrix, catalyzed by CYP27A1.
Participants
Participates
Catalyst Activity

steroid hydroxylase activity of CYP27A1 [mitochondrial matrix]

Orthologous Events
Authored
Reviewed
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