SMPD2 [plasma membrane]

Stable Identifier
R-HSA-194337
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
Sphingomyelin phosphodiesterase 2, NSMA_HUMAN
Icon
SMPD2 [plasma membrane] icon
SMPD2 [plasma membrane] icon
Locations in the PathwayBrowser
Expand all
External Reference Information
External Reference
UniProt:O60906 SMPD2
Gene Names
SMPD2
Chain
chain:1-423
Reference Genes
BioGPS Gene:6610 SMPD2
COSMIC (genes):SMPD2 SMPD2
CTD Gene:6610 SMPD2
dbSNP Gene:6610 SMPD2
ENSEMBL:ENSG00000135587 SMPD2
HGNC:11121 SMPD2
KEGG:hsa:6610 SMPD2
Monarch:6610 SMPD2
NCBI Gene:6610 SMPD2
OMIM:603498 SMPD2
UCSC:O60906 SMPD2
Reference Transcript
Other Identifiers
11723772_at
17011572
205622_PM_at
205622_at
2920917
2920918
2920919
2920920
2920921
2920922
2920924
2920925
2920926
2920927
2920928
2920929
2920930
2920931
2920932
2920933
2920934
2920935
2920936
41798_at
6610
8121418
A_14_P117845
A_23_P82162
GE55239
GO:0003824
GO:0004767
GO:0005515
GO:0005783
GO:0005886
GO:0005901
GO:0006629
GO:0006665
GO:0006672
GO:0006684
GO:0006685
GO:0008081
GO:0016787
GO:0030149
GO:0043226
GO:0046513
GO:0046872
GO:0071944
HMNXSV003050777
ILMN_1672176
PH_hs_0027128
TC06000876.hg
g4507094_3p_at
Participates
as a member of
as an input of
as a component of
Inferred To
SMPD2 [plasma membrane] (Caenorhabditis elegans)
SMPD2 [plasma membrane] (Canis familiaris)
SMPD2 [plasma membrane] (Drosophila melanogaster)
SMPD2 [plasma membrane] (Gallus gallus)
SMPD2 [plasma membrane] (Mus musculus)
SMPD2 [plasma membrane] (Rattus norvegicus)
SMPD2 [plasma membrane] (Saccharomyces cerevisiae)
SMPD2 [plasma membrane] (Schizosaccharomyces pombe)
SMPD2 [plasma membrane] (Sus scrofa)
smpd2a [plasma membrane] (Danio rerio)
Cross References
RefSeq
Guide to Pharmacology - Targets
OpenTargets
ENSEMBL
HPA
ZINC - Substances
ZINC target
PRO
Pharos - Targets
ZINC - Predictions - Purchasable
PDB
HMDB Protein
Interactors (26)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:P42898 MTHFR  1 0.564 2
 UniProt:Q05329 GAD2  2 0.556 3
 UniProt:O15173 PGRMC2  4 0.556 3
 UniProt:Q14973 SLC10A1  1 0.556 3
 UniProt:Q8NI60 COQ8A  1 0.556 3
 UniProt:Q9NRX6 KISHB      0.556 3
 UniProt:Q96AL5 Q96AL5      0.556 3
 UniProt:Q9UHI5 SLC7A8  1 0.556 3
 UniProt:P49675 STAR  2 0.556 3
 UniProt:O00622 CYR61  2 0.556 3
 UniProt:Q9ULP0-2 NDRG4      0.556 3
 UniProt:Q9NUH8 TM14B      0.556 3
 UniProt:P53367 ARFP1      0.556 3
 UniProt:Q9UKF7-2 PITPNC1      0.556 3
 IntAct:EBI-22326698 CCSB ORF ID      0.556 3
 UniProt:Q9Y371 SHLB1      0.556 3
 UniProt:P04844 RPN2  1 0.527 2
 UniProt:P49356 FNTB  1 0.527 2
 UniProt:O15482 TEX28      0.527 2
 UniProt:Q9BX97 PLVAP      0.527 2
 UniProt:Q8WW62 TMED6      0.527 2
 UniProt:Q9NRJ7 PCDBG      0.527 2
 UniProt:Q8WWF5 ZNRF4      0.527 2
 UniProt:Q9Y5E2 PCDB7      0.527 2
 UniProt:Q86UE6 LRRTM1  1 0.527 2
 UniProt:Q14392 LRC32      0.527 3
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