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PLEKHG5 [cytosol]
Stable Identifier
R-HSA-195060
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
KIAA0720 protein, Phdfg-5
Locations in the PathwayBrowser
Expand all
Signal Transduction (Homo sapiens)
Death Receptor Signaling (Homo sapiens)
p75 NTR receptor-mediated signalling (Homo sapiens)
Cell death signalling via NRAGE, NRIF and NADE (Homo sapiens)
NRAGE signals death through JNK (Homo sapiens)
p75NTR indirectly activates RAC and Cdc42 via a guanyl-nucleotide exchange factor (Homo sapiens)
GEFs [cytosol] (Homo sapiens)
PLEKHG5 [cytosol] (Homo sapiens)
Signaling by GPCR (Homo sapiens)
GPCR downstream signalling (Homo sapiens)
G alpha (12/13) signalling events (Homo sapiens)
GEFs activate RhoA,B,C (Homo sapiens)
GEFs [cytosol] (Homo sapiens)
PLEKHG5 [cytosol] (Homo sapiens)
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Homo sapiens)
Signaling by Rho GTPases (Homo sapiens)
RHO GTPase cycle (Homo sapiens)
RHOA GTPase cycle (Homo sapiens)
RHOA GEFs activate RHOA (Homo sapiens)
RHOA GEFs [cytosol] (Homo sapiens)
PLEKHG5 [cytosol] (Homo sapiens)
RND1 GTPase cycle (Homo sapiens)
RND1 binds effectors (Homo sapiens)
RND1 effectors [cytosol] (Homo sapiens)
PLEKHG5 [cytosol] (Homo sapiens)
RND1:GTP:RND1 effectors [plasma membrane] (Homo sapiens)
RND1 effectors [cytosol] (Homo sapiens)
PLEKHG5 [cytosol] (Homo sapiens)
RND3 GTPase cycle (Homo sapiens)
RND3 binds effectors (Homo sapiens)
RND3 effectors [cytosol] (Homo sapiens)
PLEKHG5 [cytosol] (Homo sapiens)
RND3:GTP:RND3 effectors [plasma membrane] (Homo sapiens)
RND3 effectors [cytosol] (Homo sapiens)
PLEKHG5 [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:O94827 PLEKHG5
Gene Names
PLEKHG5, KIAA0720
Chain
chain:1-1006
Reference Genes
BioGPS Gene:57449 PLEKHG5
COSMIC (genes):PLEKHG5 PLEKHG5
CTD Gene:57449 PLEKHG5
dbSNP Gene:57449 PLEKHG5
ENSEMBL:ENSG00000171680 PLEKHG5
HGNC:29105 PLEKHG5
KEGG:hsa:57449 PLEKHG5
Monarch:57449 PLEKHG5
NCBI Gene:57449 PLEKHG5
OMIM:611101 PLEKHG5
UCSC:O94827 PLEKHG5
Reference Transcript
RefSeq:NM_020631.4 PLEKHG5
RefSeq:NM_001042665.1 PLEKHG5
RefSeq:NM_198681.3 PLEKHG5
RefSeq:NM_001042663.1 PLEKHG5
RefSeq:NM_001265594.1 PLEKHG5
RefSeq:NM_001265593.1 PLEKHG5
RefSeq:NM_001042664.1 PLEKHG5
RefSeq:NM_001265592.1 PLEKHG5
Participates
as a member of
RHOA GEFs [cytosol] (Homo sapiens)
RND3 effectors [cytosol] (Homo sapiens)
RND1 effectors [cytosol] (Homo sapiens)
GEFs [cytosol] (Homo sapiens)
Inferred To
Plekhg5 [cytosol]
(Mus musculus)
Plekhg5 [cytosol]
(Rattus norvegicus)
CG13812 [cytosol]
(Drosophila melanogaster)
plekhg5 [cytosol]
(Xenopus tropicalis)
PLEKHG5 [cytosol]
(Bos taurus)
PLEKHG5 [cytosol]
(Canis familiaris)
PLEKHG5 [cytosol]
(Dictyostelium discoideum)
PLEKHG5 [cytosol]
(Gallus gallus)
PLEKHG5 [cytosol]
(Sus scrofa)
rhgf-2 [cytosol]
(Caenorhabditis elegans)
Cross References
ENSEMBL
ENST00000377728
,
ENST00000537245
,
ENSP00000344570
,
ENSG00000171680
,
ENST00000377725
,
ENSP00000383704
,
ENSP00000439625
,
ENSP00000501925
,
ENST00000340850
,
ENST00000675694
,
ENST00000400913
,
ENST00000400915
,
ENSP00000366969
,
ENSP00000366957
,
ENST00000377740
,
ENSP00000383706
,
ENST00000377732
,
ENSP00000366954
,
ENSP00000366961
OpenTargets
ENSG00000171680
GeneCards
PLEKHG5
HPA
ENSG00000171680-PLEKHG5
PRO
O94827
Pharos - Targets
O94827
Orphanet
PLEKHG5
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