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ARHGAP5 [cytosol]
Stable Identifier
R-HSA-195084
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
Arhgap5/p190-B
Locations in the PathwayBrowser
Expand all
Signal Transduction (Homo sapiens)
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Homo sapiens)
Signaling by Rho GTPases (Homo sapiens)
RHO GTPase cycle (Homo sapiens)
CDC42 GTPase cycle (Homo sapiens)
CDC42 GAPs stimulate CDC42 GTPase activity (Homo sapiens)
CDC42 GAPs [cytosol] (Homo sapiens)
ARHGAP5 [cytosol] (Homo sapiens)
RAC1 GTPase cycle (Homo sapiens)
RAC1 GAPs stimulate RAC1 GTPase activity (Homo sapiens)
RAC1 GAPs [cytosol] (Homo sapiens)
ARHGAP5 [cytosol] (Homo sapiens)
RAC3 GTPase cycle (Homo sapiens)
RAC3 GAPs stimulate RAC3 GTPase activity (Homo sapiens)
RAC3 GAPs [cytosol] (Homo sapiens)
ARHGAP5 [cytosol] (Homo sapiens)
RHOA GTPase cycle (Homo sapiens)
RHOA GAPs stimulate RHOA GTPase activity (Homo sapiens)
RHOA GAPs [cytosol] (Homo sapiens)
ARHGAP5 [cytosol] (Homo sapiens)
RHOB GTPase cycle (Homo sapiens)
RHOB GAPs stimulate RHOB GTPase activity (Homo sapiens)
RHOB GAPs [cytosol] (Homo sapiens)
ARHGAP5 [cytosol] (Homo sapiens)
RHOC GTPase cycle (Homo sapiens)
RHOC GAPs stimulate RHOC GTPase activity (Homo sapiens)
RHOC GAPs [cytosol] (Homo sapiens)
ARHGAP5 [cytosol] (Homo sapiens)
RHOD GTPase cycle (Homo sapiens)
RHOD GAPs stimulate RHOD GTPase activity (Homo sapiens)
RHOD GAPs [cytosol] (Homo sapiens)
ARHGAP5 [cytosol] (Homo sapiens)
RHOF GTPase cycle (Homo sapiens)
RHOF GAPs stimulate RHOF GTPase activity (Homo sapiens)
RHOF GAPs [cytosol] (Homo sapiens)
ARHGAP5 [cytosol] (Homo sapiens)
RHOG GTPase cycle (Homo sapiens)
RHOG GAPs stimulate RHOG GTPase activity (Homo sapiens)
RHOG GAPs [cytosol] (Homo sapiens)
ARHGAP5 [cytosol] (Homo sapiens)
RHOJ GTPase cycle (Homo sapiens)
RHOJ GAPs stimulate RHOJ GTPase activity (Homo sapiens)
RHOJ GAPs [cytosol] (Homo sapiens)
ARHGAP5 [cytosol] (Homo sapiens)
RHOQ GTPase cycle (Homo sapiens)
RHOQ GAPs stimulate RHOQ GTPase activity (Homo sapiens)
RHOQ GAPs [cytosol] (Homo sapiens)
ARHGAP5 [cytosol] (Homo sapiens)
RND1 GTPase cycle (Homo sapiens)
RND1 binds effectors (Homo sapiens)
RND1 effectors [cytosol] (Homo sapiens)
ARHGAP5 [cytosol] (Homo sapiens)
RND1:GTP:RND1 effectors [plasma membrane] (Homo sapiens)
RND1 effectors [cytosol] (Homo sapiens)
ARHGAP5 [cytosol] (Homo sapiens)
RND2 GTPase cycle (Homo sapiens)
RND2 binds effectors (Homo sapiens)
RND2 effectors [cytosol] (Homo sapiens)
ARHGAP5 [cytosol] (Homo sapiens)
RND2:GTP:RND2 effectors [plasma membrane] (Homo sapiens)
RND2 effectors [cytosol] (Homo sapiens)
ARHGAP5 [cytosol] (Homo sapiens)
RND3 GTPase cycle (Homo sapiens)
RND3 binds effectors (Homo sapiens)
RND3 effectors [cytosol] (Homo sapiens)
ARHGAP5 [cytosol] (Homo sapiens)
RND3:GTP:RND3 effectors [plasma membrane] (Homo sapiens)
RND3 effectors [cytosol] (Homo sapiens)
ARHGAP5 [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q13017 ARHGAP5
Gene Names
ARHGAP5, RHOGAP5
Chain
chain:1-1502
Reference Genes
BioGPS Gene:394 ARHGAP5
COSMIC (genes):ARHGAP5 ARHGAP5
CTD Gene:394 ARHGAP5
dbSNP Gene:394 ARHGAP5
ENSEMBL:ENSG00000100852 ARHGAP5
ENSEMBL_homo_sapiens_GENE:ENSG00000100852.14 ARHGAP5
HGNC:675 ARHGAP5
KEGG Gene (Homo sapiens):394 ARHGAP5
Monarch:394 ARHGAP5
NCBI Gene:394 ARHGAP5
OMIM:602680 ARHGAP5
UCSC:Q13017 ARHGAP5
Reference Transcript
RefSeq:XM_017021288.1 ARHGAP5
RefSeq:XM_005267636.3 ARHGAP5
RefSeq:NM_001173.2 ARHGAP5
RefSeq:XM_017021287.1 ARHGAP5
RefSeq:XM_005267635.3 ARHGAP5
RefSeq:NM_001030055.1 ARHGAP5
Other Identifiers
11730287_a_at
11730288_at
11730289_a_at
11730290_x_at
11730291_a_at
11730292_a_at
11754739_a_at
1552627_PM_a_at
1552627_a_at
16783215
2029_at
217936_PM_at
217936_at
233849_PM_s_at
233849_s_at
235635_PM_at
235635_at
3002587
3002589
3002590
3002591
3002593
3002599
3002602
3002603
3002605
3002606
3002607
3002610
3002614
3002616
3002619
3531484
3531485
3531486
3531491
3531492
3531493
3531494
3531495
3531504
3531505
3531512
3531513
3531514
3531517
3531518
3531519
3531520
3531521
3531522
3531523
3531524
3531525
3531526
3531527
3531528
3531529
3531530
394
39927_at
46831_at
49263_at
60527_at
7973840
91365_i_at
A_23_P48535
A_33_P3242483
A_33_P3386459
GE62814
GE797802
GE80989
GO:0002053
GO:0003824
GO:0003924
GO:0005096
GO:0005515
GO:0005737
GO:0005783
GO:0005829
GO:0005886
GO:0007155
GO:0007165
GO:0007266
GO:0008361
GO:0010631
GO:0010634
GO:0016020
GO:0016477
GO:0016787
GO:0023052
GO:0030879
GO:0042169
GO:0043226
GO:0048856
GO:0048870
GO:0051056
GO:0098772
HMNXSV003007040
Hs.267831.0.S2_3p_at
Hs.267831.1.S1_3p_a_at
Hs.47026.0.A1_3p_at
Hs2.267831.1.S1_3p_s_at
ILMN_2322747
TC14000205.hg
TC14001636.hg
U17032_at
Participates
as a member of
RND2 effectors [cytosol] (Homo sapiens)
RHOA GAPs [cytosol] (Homo sapiens)
RND3 effectors [cytosol] (Homo sapiens)
RHOC GAPs [cytosol] (Homo sapiens)
RHOB GAPs [cytosol] (Homo sapiens)
RND1 effectors [cytosol] (Homo sapiens)
as a candidate of
RHOQ GAPs [cytosol] (Homo sapiens)
CDC42 GAPs [cytosol] (Homo sapiens)
RHOD GAPs [cytosol] (Homo sapiens)
RAC1 GAPs [cytosol] (Homo sapiens)
RHOF GAPs [cytosol] (Homo sapiens)
RHOG GAPs [cytosol] (Homo sapiens)
RHOJ GAPs [cytosol] (Homo sapiens)
RAC3 GAPs [cytosol] (Homo sapiens)
Inferred To
RhoGAPp190 [cytosol]
(Drosophila melanogaster)
Arhgap5 [cytosol]
(Mus musculus)
Arhgap5 [cytosol]
(Rattus norvegicus)
arhgap5 [cytosol]
(Danio rerio)
arhgap5 [cytosol]
(Xenopus tropicalis)
rga-5 [cytosol]
(Caenorhabditis elegans)
ARHGAP5 [cytosol]
(Bos taurus)
ARHGAP5 [cytosol]
(Canis familiaris)
ARHGAP5 [cytosol]
(Gallus gallus)
ARHGAP5 [cytosol]
(Sus scrofa)
Cross References
RefSeq
XP_005267693.1
,
NP_001025226.1
,
XP_005267692.1
,
XP_016876776.1
,
NP_001164.2
,
XP_016876777.1
OpenTargets
ENSG00000100852
GeneCards
Q13017
HPA
ENSG00000100852-ARHGAP5
Ensembl
ENST00000556611
,
ENST00000345122
,
ENSP00000371897
,
ENSP00000452222
,
ENST00000539826
,
ENSP00000407395
,
ENSP00000441692
,
ENST00000396582
,
ENSP00000379827
,
ENST00000433497
,
ENSG00000100852
PRO
Q13017
Pharos - Targets
Q13017
PDB
2EE4
,
2EE5
,
5U4V
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q9HAU4 SMURF2
2
SMURF2 [nucleoplasm]
(R-HSA-178202)
SMURF2 [cytosol]
(R-HSA-173537)
0.547
2
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