Reactome | ARHGEF11 [cytosol]

ARHGEF11 [cytosol]

Stable Identifier

R-HSA-195102

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

PDZ-RhoGEF

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External Reference Information

External Reference

UniProt:O15085 ARHGEF11

Gene Names

ARHGEF11, KIAA0380

Chain

chain:1-1522

Reference Genes

BioGPS Gene:9826 ARHGEF11

COSMIC (genes):ARHGEF11 ARHGEF11

CTD Gene:9826 ARHGEF11

dbSNP Gene:9826 ARHGEF11

ENSEMBL:ENSG00000132694 ARHGEF11

HGNC:14580 ARHGEF11

KEGG:hsa:9826 ARHGEF11

Monarch:9826 ARHGEF11

NCBI Gene:9826 ARHGEF11

OMIM:605708 ARHGEF11

UCSC:O15085 ARHGEF11

Reference Transcript

Participates

as a member of

as a candidate of

Inferred To

RhoGEF2 [cytosol] (Drosophila melanogaster)

arhgef11 [cytosol] (Danio rerio)

arhgef11 [cytosol] (Xenopus tropicalis)

rhgf-1 [cytosol] (Caenorhabditis elegans)

ARHGEF11 [cytosol] (Bos taurus)

ARHGEF11 [cytosol] (Canis familiaris)

ARHGEF11 [cytosol] (Gallus gallus)

ARHGEF11 [cytosol] (Sus scrofa)

Arhgef11 [cytosol] (Mus musculus)

Arhgef11 [cytosol] (Rattus norvegicus)

Cross References

ENSEMBL

ENSP00000357177, ENSG00000132694, ENST00000361409, ENSP00000354644, ENST00000368194

OpenTargets

ENSG00000132694

GeneCards

ARHGEF11

HPA

ENSG00000132694-ARHGEF11

PRO

O15085

Pharos - Targets

O15085

GlyGen

O15085

HMDB Protein

HMDBP11486

PDB

3T06, 2DLS, 5TYT, 1HTJ, 1XCG, 5E6P, 5JHH, 5JHG, 3KZ1

Interactors (1)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P61586 RHOA	6	RHOA [plasma membrane] (R-HSA-194510) RHOA [cell junction] (R-HSA-2134503) RHOA [cytosol] (R-HSA-194866) RHOA [endoplasmic reticulum membrane] (R-HSA-5672082) RHOA [secretory granule membrane] (R-HSA-6804980) RHOA [ficolin-1-rich granule membrane] (R-HSA-6804971)	0.903	12