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ARHGAP32 [cytosol]
Stable Identifier
R-HSA-195134
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
Grit
Locations in the PathwayBrowser
Expand all
Signal Transduction (Homo sapiens)
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Homo sapiens)
Signaling by Rho GTPases (Homo sapiens)
RHO GTPase cycle (Homo sapiens)
CDC42 GTPase cycle (Homo sapiens)
CDC42 GAPs stimulate CDC42 GTPase activity (Homo sapiens)
CDC42 GAPs [cytosol] (Homo sapiens)
ARHGAP32 [cytosol] (Homo sapiens)
RAC1 GTPase cycle (Homo sapiens)
RAC1 GAPs stimulate RAC1 GTPase activity (Homo sapiens)
RAC1 GAPs [cytosol] (Homo sapiens)
ARHGAP32 [cytosol] (Homo sapiens)
RAC2 GTPase cycle (Homo sapiens)
RAC2 GAPs stimulate RAC2 GTPase activity (Homo sapiens)
RAC2 GAPs [cytosol] (Homo sapiens)
ARHGAP32 [cytosol] (Homo sapiens)
RAC3 GTPase cycle (Homo sapiens)
RAC3 GAPs stimulate RAC3 GTPase activity (Homo sapiens)
RAC3 GAPs [cytosol] (Homo sapiens)
ARHGAP32 [cytosol] (Homo sapiens)
RHOA GTPase cycle (Homo sapiens)
RHOA GAPs stimulate RHOA GTPase activity (Homo sapiens)
RHOA GAPs [cytosol] (Homo sapiens)
ARHGAP32 [cytosol] (Homo sapiens)
RHOB GTPase cycle (Homo sapiens)
RHOB GAPs stimulate RHOB GTPase activity (Homo sapiens)
RHOB GAPs [cytosol] (Homo sapiens)
ARHGAP32 [cytosol] (Homo sapiens)
RHOC GTPase cycle (Homo sapiens)
RHOC GAPs stimulate RHOC GTPase activity (Homo sapiens)
RHOC GAPs [cytosol] (Homo sapiens)
ARHGAP32 [cytosol] (Homo sapiens)
RHOD GTPase cycle (Homo sapiens)
RHOD GAPs stimulate RHOD GTPase activity (Homo sapiens)
RHOD GAPs [cytosol] (Homo sapiens)
ARHGAP32 [cytosol] (Homo sapiens)
RHOF GTPase cycle (Homo sapiens)
RHOF GAPs stimulate RHOF GTPase activity (Homo sapiens)
RHOF GAPs [cytosol] (Homo sapiens)
ARHGAP32 [cytosol] (Homo sapiens)
RHOG GTPase cycle (Homo sapiens)
RHOG GAPs stimulate RHOG GTPase activity (Homo sapiens)
RHOG GAPs [cytosol] (Homo sapiens)
ARHGAP32 [cytosol] (Homo sapiens)
RHOJ GTPase cycle (Homo sapiens)
RHOJ GAPs stimulate RHOJ GTPase activity (Homo sapiens)
RHOJ GAPs [cytosol] (Homo sapiens)
ARHGAP32 [cytosol] (Homo sapiens)
RHOQ GTPase cycle (Homo sapiens)
RHOQ GAPs stimulate RHOQ GTPase activity (Homo sapiens)
RHOQ GAPs [cytosol] (Homo sapiens)
ARHGAP32 [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:A7KAX9 ARHGAP32
Gene Names
ARHGAP32, GRIT, KIAA0712, RICS
Chain
chain:1-2087
Reference Genes
BioGPS Gene:9743 ARHGAP32
COSMIC (genes):ARHGAP32 ARHGAP32
CTD Gene:9743 ARHGAP32
dbSNP Gene:9743 ARHGAP32
ENSEMBL:ENSG00000134909 ARHGAP32
ENSEMBL_homo_sapiens_GENE:ENSG00000134909.19 ARHGAP32
HGNC:17399 ARHGAP32
KEGG Gene (Homo sapiens):9743 ARHGAP32
Monarch:9743 ARHGAP32
NCBI Gene:9743 ARHGAP32
OMIM:608541 ARHGAP32
UCSC:A7KAX9 ARHGAP32
Reference Transcript
RefSeq:NM_001142685.1 ARHGAP32
RefSeq:NM_014715.3 ARHGAP32
Other Identifiers
11726652_a_at
11726653_a_at
11755001_a_at
16746057
203431_PM_s_at
203431_s_at
210791_PM_s_at
210791_s_at
229648_PM_at
229648_at
242196_PM_at
242196_at
3397867
3397868
3397870
3397872
3397874
3397876
3397878
3397879
3397880
3397881
3397882
3397884
3397885
3397886
3397887
3397889
3397890
3397891
3397894
3397895
3397896
3397897
3397899
3397900
3397902
3397904
3397905
3397911
3397912
3397914
3397916
3397917
3397918
3397919
3397920
3397924
3397930
3397932
3397937
3397940
41455_at
58906_at
7952641
80170_at
9743
A_19_P00811843
A_23_P161686
A_24_P135344
A_24_P42436
GE53436
GO:0000139
GO:0001650
GO:0005096
GO:0005515
GO:0005634
GO:0005654
GO:0005730
GO:0005737
GO:0005768
GO:0005783
GO:0005789
GO:0005794
GO:0005829
GO:0005856
GO:0005938
GO:0007165
GO:0007264
GO:0008289
GO:0010008
GO:0014069
GO:0015629
GO:0016020
GO:0023052
GO:0031410
GO:0035091
GO:0042995
GO:0043197
GO:0043226
GO:0045202
GO:0051056
GO:0098772
GO:1901981
HMNXSV003024450
Hs.222184.0.A1_3p_at
Hs.23798.0.A1_3p_at
ILMN_1722726
PH_hs_0025780
PH_hs_0040284
TC11002446.hg
g12802987_3p_a_at
g7662261_3p_a_at
Participates
as a candidate of
RHOA GAPs [cytosol] (Homo sapiens)
RHOC GAPs [cytosol] (Homo sapiens)
RHOQ GAPs [cytosol] (Homo sapiens)
CDC42 GAPs [cytosol] (Homo sapiens)
RAC2 GAPs [cytosol] (Homo sapiens)
RAC1 GAPs [cytosol] (Homo sapiens)
RHOF GAPs [cytosol] (Homo sapiens)
RHOB GAPs [cytosol] (Homo sapiens)
RHOG GAPs [cytosol] (Homo sapiens)
RHOJ GAPs [cytosol] (Homo sapiens)
RAC3 GAPs [cytosol] (Homo sapiens)
as a member of
RHOD GAPs [cytosol] (Homo sapiens)
Inferred To
ARHGAP32 [cytosol]
(Bos taurus)
ARHGAP32 [cytosol]
(Canis familiaris)
ARHGAP32 [cytosol]
(Sus scrofa)
Arhgap32 [cytosol]
(Mus musculus)
Arhgap32 [cytosol]
(Rattus norvegicus)
CdGAPr [cytosol]
(Drosophila melanogaster)
arhgap32 [cytosol]
(Xenopus tropicalis)
Cross References
RefSeq
NP_055530.2
,
NP_001136157.1
OpenTargets
ENSG00000134909
HPA
ENSG00000134909-ARHGAP32
GeneCards
A7KAX9
Ensembl
ENSG00000134909
,
ENSP00000376425
,
ENSP00000310561
,
ENST00000310343
,
ENST00000392657
,
ENSP00000432862
,
ENST00000527272
PRO
A7KAX9
Pharos - Targets
A7KAX9
PDB
3IUG
HMDB Protein
HMDBP07971
Interactors (9)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P06241 FYN
6
p-S21,Y420-FYN [cytosol]
(R-HSA-5218745)
p-Y531-FYN [cytosol]
(R-HSA-391819)
MyrG2-PalmC3,6-FYN [plasma membrane]
(R-HSA-9606873)
p-Y420-FYN [cytosol]
(R-HSA-391821)
MyrG-p-Y420-FYN [plasma membrane]
(R-HSA-1810410)
FYN [cytosol]
(R-HSA-200917)
0.633
4
UniProt:P31946 YWHAB
1
YWHAB [cytosol]
(R-HSA-48888)
0.615
4
UniProt:P46108 CRK
1
CRK [cytosol]
(R-HSA-2980677)
0.59
3
UniProt:P50458 LHX2
1
LHX2 [nucleoplasm]
(R-HSA-9011100)
0.556
3
UniProt:Q08117 TLE5
1
AES [nucleoplasm]
(R-HSA-4648963)
0.556
3
UniProt:O43639 NCK2
1
NCK2 [cytosol]
(R-HSA-204885)
0.556
3
UniProt:P31947 SFN
1
SFN [cytosol]
(R-HSA-1445105)
0.536
3
UniProt:P63104 YWHAZ
2
YWHAZ [nucleoplasm]
(R-HSA-450469)
YWHAZ [cytosol]
(R-HSA-206099)
0.483
2
UniProt:P62258 YWHAE
1
YWHAE [cytosol]
(R-HSA-194368)
0.483
3
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