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DLC1 [cytosol]
Stable Identifier
R-HSA-195140
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
ARHGAP7, Dlc-1
Locations in the PathwayBrowser
Expand all
Signal Transduction (Homo sapiens)
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Homo sapiens)
Signaling by Rho GTPases (Homo sapiens)
RHO GTPase cycle (Homo sapiens)
CDC42 GTPase cycle (Homo sapiens)
CDC42 GAPs stimulate CDC42 GTPase activity (Homo sapiens)
CDC42 GAPs [cytosol] (Homo sapiens)
DLC1 [cytosol] (Homo sapiens)
RAC1 GTPase cycle (Homo sapiens)
RAC1 GAPs stimulate RAC1 GTPase activity (Homo sapiens)
RAC1 GAPs [cytosol] (Homo sapiens)
DLC1 [cytosol] (Homo sapiens)
RHOA GTPase cycle (Homo sapiens)
RHOA GAPs stimulate RHOA GTPase activity (Homo sapiens)
RHOA GAPs [cytosol] (Homo sapiens)
DLC1 [cytosol] (Homo sapiens)
RHOB GTPase cycle (Homo sapiens)
RHOB GAPs stimulate RHOB GTPase activity (Homo sapiens)
RHOB GAPs [cytosol] (Homo sapiens)
DLC1 [cytosol] (Homo sapiens)
RHOC GTPase cycle (Homo sapiens)
RHOC GAPs stimulate RHOC GTPase activity (Homo sapiens)
RHOC GAPs [cytosol] (Homo sapiens)
DLC1 [cytosol] (Homo sapiens)
RHOQ GTPase cycle (Homo sapiens)
RHOQ GAPs stimulate RHOQ GTPase activity (Homo sapiens)
RHOQ GAPs [cytosol] (Homo sapiens)
DLC1 [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q96QB1 DLC1
Gene Names
DLC1, ARHGAP7, KIAA1723, STARD12
Chain
chain:1-1528
Reference Genes
BioGPS Gene:10395 DLC1
COSMIC (genes):DLC1 DLC1
CTD Gene:10395 DLC1
dbSNP Gene:10395 DLC1
ENSEMBL:ENSG00000164741 DLC1
HGNC:2897 DLC1
Monarch:10395 DLC1
NCBI Gene:10395 DLC1
OMIM:604258 DLC1
UCSC:Q96QB1 DLC1
Reference Transcript
RefSeq:NM_001348083.1 DLC1
RefSeq:XM_005273374.1 DLC1
RefSeq:NM_001164271.1 DLC1
RefSeq:NM_024767.3 DLC1
RefSeq:NM_001348084.1 DLC1
RefSeq:NM_001348081.1 DLC1
RefSeq:NM_006094.4 DLC1
RefSeq:NM_001348082.1 DLC1
RefSeq:NM_182643.2 DLC1
RefSeq:NM_001316668.1 DLC1
Other Identifiers
10395
11721488_a_at
11739303_a_at
11740817_a_at
11755691_a_at
11761363_at
17074887
210762_PM_s_at
210762_s_at
220511_PM_s_at
220511_s_at
220512_PM_at
220512_at
224822_PM_at
224822_at
242631_PM_x_at
242631_x_at
3125117
3125118
3125119
3125120
3125121
3125122
3125125
3125126
3125127
3125129
3125131
3125132
3125133
3125134
3125135
3125136
3125137
3125138
3125141
3125142
3125144
3125149
3125155
3125156
3125185
3125186
3125218
3125219
3125220
3125230
3125231
3125232
3125233
3125254
3125257
3125258
3125277
3125278
3125279
3125280
3125281
3125282
3125283
3125299
37951_at
46303_at
49889_at
64873_at
71123_at
8149413
A_23_P112016
A_23_P252721
A_24_P940115
GE54267
GE56511
GE85281
GO:0001843
GO:0003007
GO:0005096
GO:0005515
GO:0005634
GO:0005737
GO:0005783
GO:0005829
GO:0005856
GO:0005901
GO:0005925
GO:0006915
GO:0006919
GO:0007010
GO:0007165
GO:0008285
GO:0008289
GO:0008360
GO:0012501
GO:0016020
GO:0021575
GO:0030036
GO:0030336
GO:0030864
GO:0030900
GO:0032587
GO:0032956
GO:0034330
GO:0035023
GO:0035024
GO:0035307
GO:0042169
GO:0043226
GO:0043231
GO:0045121
GO:0048041
GO:0048856
GO:0051056
GO:0051497
GO:0051895
GO:0070161
GO:0098772
GO:1900119
HMNXSV003001205
HMNXSV003040171
HMNXSV003056680
Hs.212566.0.A1_3p_at
Hs.8700.1.S2_3p_at
ILMN_1698020
ILMN_1729409
PH_hs_0000915
TC08001000.hg
TC08001001.hg
TC08002235.hg
g13376110_3p_at
g13376110_3p_x_at
g2559001_3p_a_at
p15607
Participates
as a member of
RHOA GAPs [cytosol] (Homo sapiens)
RHOC GAPs [cytosol] (Homo sapiens)
RHOQ GAPs [cytosol] (Homo sapiens)
RHOB GAPs [cytosol] (Homo sapiens)
as a candidate of
CDC42 GAPs [cytosol] (Homo sapiens)
RAC1 GAPs [cytosol] (Homo sapiens)
Inferred To
dlc1 [cytosol]
(Xenopus tropicalis)
cv-c [cytosol]
(Drosophila melanogaster)
Dlc1 [cytosol]
(Mus musculus)
Dlc1 [cytosol]
(Rattus norvegicus)
gei-1 [cytosol]
(Caenorhabditis elegans)
DLC1 [cytosol]
(Bos taurus)
DLC1 [cytosol]
(Canis familiaris)
DLC1 [cytosol]
(Gallus gallus)
DLC1 [cytosol]
(Sus scrofa)
Cross References
ENSEMBL
ENST00000520226
,
ENST00000358919
,
ENST00000511869
,
ENSP00000428028
,
ENST00000316609
,
ENST00000276297
,
ENST00000512044
,
ENSP00000321034
,
ENSP00000351797
,
ENSP00000276297
,
ENSP00000422595
,
ENSP00000425878
OpenTargets
ENSG00000164741
HPA
ENSG00000164741-DLC1
PRO
Q96QB1
Pharos - Targets
Q96QB1
GlyGen
Q96QB1
PDB
2LOZ
,
2GYT
,
3KUQ
,
2KAP
,
5FZT
,
2DKY
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P20936 RASA1
1
RASA1 [cytosol]
(R-HSA-186833)
0.715
7
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