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p-S45 CTNNB1:p-Axin:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol]
Stable Identifier
R-HSA-195277
Type
Complex
Species
Homo sapiens
Compartment
cytosol
Synonyms
pS45-beta-catenin:destruction complex
Locations in the PathwayBrowser
Expand all
Signal Transduction (Homo sapiens)
Signaling by WNT (Homo sapiens)
Degradation of beta-catenin by the destruction complex (Homo sapiens)
Beta-catenin phosphorylation cascade (Homo sapiens)
Phosphorylation of beta-catenin at Ser45 by CK1 alpha (Homo sapiens)
p-S45 CTNNB1:p-Axin:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Homo sapiens)
Phosphorylation of phospho-(Ser45 ) at Thr 41 by GSK-3 (Homo sapiens)
p-S45 CTNNB1:p-Axin:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Homo sapiens)
Participants
components
p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol]
(Homo sapiens)
p-S45 CTNNB1 [cytosol]
(Homo sapiens)
Participates
as an output of
Phosphorylation of beta-catenin at Ser45 by CK1 alpha (Homo sapiens)
as an input of
Phosphorylation of phospho-(Ser45 ) at Thr 41 by GSK-3 (Homo sapiens)
Inferred To
p-S45 CTNNB1:p-Axin:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol]
(Bos taurus)
p-S45 CTNNB1:p-Axin:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol]
(Caenorhabditis elegans)
p-S45 CTNNB1:p-Axin:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol]
(Canis familiaris)
p-S45 CTNNB1:p-Axin:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol]
(Drosophila melanogaster)
p-S45 CTNNB1:p-Axin:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol]
(Gallus gallus)
p-S45 CTNNB1:p-Axin:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol]
(Mus musculus)
p-S45 CTNNB1:p-Axin:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol]
(Rattus norvegicus)
p-S45 CTNNB1:p-Axin:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol]
(Sus scrofa)
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