Phosphorylation of phospho-(Ser45 ) at Thr 41 by GSK-3

Stable Identifier
R-HSA-195287
Type
Reaction [transition]
Species
Homo sapiens
Compartment
ReviewStatus
5/5
Locations in the PathwayBrowser
General
SVG |   | PPTX  | SBGN
Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout
Following CKI-mediated phosphorylation at Ser45, beta-catenin is phosphorylated by GSK3 at Thr41.
Literature References
PubMed ID Title Journal Year
11955436 Control of beta-catenin phosphorylation/degradation by a dual-kinase mechanism

Zhang, Z, Baeg, GH, Lin, X, Tan, Y, Li, Y, He, X, Semenov, M, Han, C, Liu, C

Cell 2002
Participants
Participates
Catalyst Activity

protein serine/threonine kinase activity of p-S45 CTNNB1:p-Axin:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol]

This event is regulated
Orthologous Events
Authored
Reviewed
Created
Cite Us!