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RAC3 [plasma membrane]
Stable Identifier
R-HSA-195338
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
Rac3
Locations in the PathwayBrowser
Expand all
Signal Transduction (Homo sapiens)
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Homo sapiens)
Signaling by Rho GTPases (Homo sapiens)
RHO GTPase cycle (Homo sapiens)
RAC3 GTPase cycle (Homo sapiens)
RAC3 GAPs stimulate RAC3 GTPase activity (Homo sapiens)
RAC3:GDP [plasma membrane] (Homo sapiens)
RAC3 [plasma membrane] (Homo sapiens)
RAC3:GTP [plasma membrane] (Homo sapiens)
RAC3 [plasma membrane] (Homo sapiens)
RAC3 GDIs block activation of RAC3 (Homo sapiens)
RAC3:GDP [plasma membrane] (Homo sapiens)
RAC3 [plasma membrane] (Homo sapiens)
RAC3 GEFs activate RAC3 (Homo sapiens)
RAC3:GDP [plasma membrane] (Homo sapiens)
RAC3 [plasma membrane] (Homo sapiens)
RAC3:GTP [plasma membrane] (Homo sapiens)
RAC3 [plasma membrane] (Homo sapiens)
RAC3 binds effectors at the plasma membrane (Homo sapiens)
RAC3:GTP [plasma membrane] (Homo sapiens)
RAC3 [plasma membrane] (Homo sapiens)
RAC3:GTP:RAC3 effectors [plasma membrane] (Homo sapiens)
RAC3:GTP [plasma membrane] (Homo sapiens)
RAC3 [plasma membrane] (Homo sapiens)
RAC3 translocates to the endoplasmic reticulum membrane (Homo sapiens)
RAC3:GTP [plasma membrane] (Homo sapiens)
RAC3 [plasma membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:P60763 RAC3
Gene Names
RAC3
Chain
chain:1-189, propeptide:190-192
Reference Genes
BioGPS Gene:5881 RAC3
COSMIC (genes):RAC3 RAC3
CTD Gene:5881 RAC3
dbSNP Gene:5881 RAC3
ENSEMBL:ENSG00000169750 RAC3
HGNC:9803 RAC3
KEGG:hsa:5881 RAC3
Monarch:5881 RAC3
NCBI Gene:5881 RAC3
OMIM:602050 RAC3
UCSC:P60763 RAC3
Reference Transcript
RefSeq:NM_005052.2 RAC3
Other Identifiers
11729313_at
16838977
206103_PM_at
206103_at
3738472
3738473
3738474
3738475
3738476
3738477
3738478
3738479
3738480
3738481
3738482
3738483
39965_at
5881
8010737
A_14_P133812
A_23_P125001
A_33_P3295523
GE54093
GO:0003824
GO:0003924
GO:0003925
GO:0005515
GO:0005525
GO:0005737
GO:0005789
GO:0005829
GO:0005856
GO:0005886
GO:0007010
GO:0007015
GO:0007163
GO:0007264
GO:0008045
GO:0008360
GO:0012505
GO:0014041
GO:0016055
GO:0016601
GO:0016787
GO:0019901
GO:0021894
GO:0022604
GO:0023052
GO:0030027
GO:0030031
GO:0030036
GO:0030426
GO:0030865
GO:0031175
GO:0031410
GO:0031941
GO:0032956
GO:0033630
GO:0035556
GO:0042995
GO:0043005
GO:0043020
GO:0043025
GO:0043226
GO:0043652
GO:0045730
GO:0048306
GO:0048471
GO:0048856
GO:0048870
GO:0048873
GO:0050877
GO:0050885
GO:0050905
GO:0051932
GO:0060326
GO:0061024
GO:0070062
GO:0071944
GO:0098772
GO:0098794
GO:0098974
GO:0098978
GO:0150052
GO:1900026
GO:1902622
HMNXSV003002092
HMNXSV003022059
ILMN_1693340
TC17000944.hg
g4826961_3p_at
g4826961_3p_x_at
Participates
as a component of
RAC3:GDP [plasma membrane] (Homo sapiens)
RAC3:GTP [plasma membrane] (Homo sapiens)
Other forms of this molecule
RAC3 [endoplasmic reticulum membrane]
RAC3 [cytosol]
Inferred To
RAC3 [plasma membrane]
(Bos taurus)
RAC3 [plasma membrane]
(Canis familiaris)
RAC3 [plasma membrane]
(Mus musculus)
RAC3 [plasma membrane]
(Sus scrofa)
Homologues of RAC3 [plasma membrane]
(Danio rerio)
rac3b [plasma membrane]
(Danio rerio)
RAC1 [plasma membrane]
(Caenorhabditis elegans)
RAC1 [plasma membrane]
(Dictyostelium discoideum)
RAC1 [plasma membrane]
(Drosophila melanogaster)
rac3a [plasma membrane]
(Danio rerio)
rac3 [plasma membrane]
(Xenopus tropicalis)
cRac1B [plasma membrane]
(Gallus gallus)
Cross References
RefSeq
NP_005043.1
ENSEMBL
ENST00000306897
,
ENSP00000304283
OpenTargets
ENSG00000169750
HPA
ENSG00000169750-RAC3
PRO
P60763
Pharos - Targets
P60763
GlyGen
P60763
HMDB Protein
HMDBP08516
PDB
2C2H
,
2QME
,
2G0N
,
6TM1
,
2IC5
,
2OV2
Interactors (6)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P03372 ESR1
10
ESR1 [cytosol]
(R-HSA-9020968)
ESR1 [nucleoplasm]
(R-HSA-446168)
Me260-PalmS-ESR1 [plasma membrane]
(R-HSA-9637788)
PalmS-ESR1 [plasma membrane]
(R-HSA-9021057)
PalmS-ESR1 [cytosol]
(R-HSA-9020974)
Me260-ESR1 [cytosol]
(R-HSA-9632177)
p-S167-ESR1 [cytosol]
(R-HSA-9841254)
p-S167-ESR1 [nucleoplasm]
(R-HSA-9841867)
monoSUMO1-5K-ESR1 [nucleoplasm]
(R-HSA-4090302)
p-S118-ESR1 [nucleoplasm]
(R-HSA-9024210)
0.639
5
UniProt:P53365 ARFIP2
1
ARFIP2 [cytosol]
(R-HSA-6813848)
0.556
3
UniProt:P52565 ARHGDIA
1
ARHGDIA [cytosol]
(R-HSA-194478)
0.547
2
UniProt:P52306 RAP1GDS1
1
RAP1GDS1 [mitochondrial outer membrane]
(R-HSA-9693756)
0.527
2
UniProt:P30825 SLC7A1
1
SLC7A1 [plasma membrane]
(R-HSA-375771)
0.527
2
UniProt:P63000 RAC1
6
RAC1 [plasma membrane]
(R-HSA-351141)
RAC1 [cytosol]
(R-HSA-442615)
GGC-PalmC-RAC1 [plasma membrane]
(R-HSA-2316446)
RAC1 [ficolin-1-rich granule membrane]
(R-HSA-6804802)
RAC1 [secretory granule membrane]
(R-HSA-6804770)
RAC1 [endoplasmic reticulum membrane]
(R-HSA-5672076)
0.527
2
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