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Phosphorylated ERBB2:ERBB3 heterodimers [plasma membrane]
Stable Identifier
R-HSA-1963572
Type
Set [CandidateSet]
Species
Homo sapiens
Compartment
plasma membrane
Locations in the PathwayBrowser
Expand all
Disease (Homo sapiens)
Diseases of signal transduction by growth factor receptors and second messengers (Homo sapiens)
PI3K/AKT Signaling in Cancer (Homo sapiens)
Constitutive Signaling by Aberrant PI3K in Cancer (Homo sapiens)
PI3K inhibitors block PI3K catalytic activity (Homo sapiens)
PI3K Inhibitors:PI3K [cytosol] (Homo sapiens)
PI3K mutants,Activator:PI3K [plasma membrane] (Homo sapiens)
Activator:PI3K [plasma membrane] (Homo sapiens)
NRG1/2:p-ERBB3:p-ERBB2:PI3K [plasma membrane] (Homo sapiens)
NRG1/2:p-ERBB3:p-ERBB2:PIK3R1 [plasma membrane] (Homo sapiens)
Phosphorylated ERBB2:ERBB3 heterodimers [plasma membrane] (Homo sapiens)
PI3K mutants,Activator:PI3K [plasma membrane] (Homo sapiens)
Activator:PI3K [plasma membrane] (Homo sapiens)
NRG1/2:p-ERBB3:p-ERBB2:PI3K [plasma membrane] (Homo sapiens)
NRG1/2:p-ERBB3:p-ERBB2:PIK3R1 [plasma membrane] (Homo sapiens)
Phosphorylated ERBB2:ERBB3 heterodimers [plasma membrane] (Homo sapiens)
Signal Transduction (Homo sapiens)
Intracellular signaling by second messengers (Homo sapiens)
PIP3 activates AKT signaling (Homo sapiens)
Negative regulation of the PI3K/AKT network (Homo sapiens)
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling (Homo sapiens)
PI3K phosphorylates PIP2 to PIP3 (Homo sapiens)
Activator:PI3K [plasma membrane] (Homo sapiens)
NRG1/2:p-ERBB3:p-ERBB2:PI3K [plasma membrane] (Homo sapiens)
NRG1/2:p-ERBB3:p-ERBB2:PIK3R1 [plasma membrane] (Homo sapiens)
Phosphorylated ERBB2:ERBB3 heterodimers [plasma membrane] (Homo sapiens)
PI3K phosphorylates PIP2 to PIP3 (Homo sapiens)
Activator:PI3K [plasma membrane] (Homo sapiens)
NRG1/2:p-ERBB3:p-ERBB2:PI3K [plasma membrane] (Homo sapiens)
NRG1/2:p-ERBB3:p-ERBB2:PIK3R1 [plasma membrane] (Homo sapiens)
Phosphorylated ERBB2:ERBB3 heterodimers [plasma membrane] (Homo sapiens)
Signaling by Receptor Tyrosine Kinases (Homo sapiens)
Signaling by ERBB2 (Homo sapiens)
Downregulation of ERBB2 signaling (Homo sapiens)
Downregulation of ERBB2:ERBB3 signaling (Homo sapiens)
RNF41 binds neuregulin-activated ERBB3 (Homo sapiens)
NRG1/2:p-10Y-ERBB3:p-ERBB2:RNF41 [plasma membrane] (Homo sapiens)
Phosphorylated ERBB2:ERBB3 heterodimers [plasma membrane] (Homo sapiens)
Phosphorylated ERBB2:ERBB3 heterodimers [plasma membrane] (Homo sapiens)
RNF41 ubiquitinates activated ERBB3 (Homo sapiens)
NRG1/2:Ub-p-10Y-ERBB3:p-ERBB2 [plasma membrane] (Homo sapiens)
Phosphorylated ERBB2:ERBB3 heterodimers [plasma membrane] (Homo sapiens)
NRG1/2:p-10Y-ERBB3:p-ERBB2:RNF41 [plasma membrane] (Homo sapiens)
Phosphorylated ERBB2:ERBB3 heterodimers [plasma membrane] (Homo sapiens)
GRB7 events in ERBB2 signaling (Homo sapiens)
GRB7 binds phosphorylated heterodimer of ERBB2 and ERBB3 (Homo sapiens)
NRG1/2:p-10Y-ERBB3:p-ERBB2:GRB7 [plasma membrane] (Homo sapiens)
Phosphorylated ERBB2:ERBB3 heterodimers [plasma membrane] (Homo sapiens)
Phosphorylated ERBB2:ERBB3 heterodimers [plasma membrane] (Homo sapiens)
PI3K events in ERBB2 signaling (Homo sapiens)
Binding of PI3K to ERBB2:p-ERBB3 heterodimer (Homo sapiens)
NRG1/2:p-ERBB3:p-ERBB2:PI3K [plasma membrane] (Homo sapiens)
NRG1/2:p-ERBB3:p-ERBB2:PIK3R1 [plasma membrane] (Homo sapiens)
Phosphorylated ERBB2:ERBB3 heterodimers [plasma membrane] (Homo sapiens)
Phosphorylated ERBB2:ERBB3 heterodimers [plasma membrane] (Homo sapiens)
PIP2 to PIP3 conversion by PI3K bound to phosphorylated heterodimer of ERBB2 and ERBB3 (Homo sapiens)
NRG1/2:p-ERBB3:p-ERBB2:PI3K [plasma membrane] (Homo sapiens)
NRG1/2:p-ERBB3:p-ERBB2:PIK3R1 [plasma membrane] (Homo sapiens)
Phosphorylated ERBB2:ERBB3 heterodimers [plasma membrane] (Homo sapiens)
Participants
members
NRG1/2:p-10Y-ERBB3:p-Y-ERBB2 [plasma membrane]
(Homo sapiens)
candidates
NRG1/2:p-10Y-ERBB3:p-Y,877-ERBB2 [plasma membrane]
(Homo sapiens)
Participates
as a component of
NRG1/2:p-10Y-ERBB3:p-ERBB2:GRB7 [plasma membrane] (Homo sapiens)
NRG1/2:Ub-p-10Y-ERBB3:p-ERBB2 [plasma membrane] (Homo sapiens)
NRG1/2:p-10Y-ERBB3:p-ERBB2:RNF41 [plasma membrane] (Homo sapiens)
Shc1:Phosphorylated ERBB2:ERBB3 heterodimers [plasma membrane] (Homo sapiens)
NRG1/2:p-ERBB3:p-ERBB2:PIK3R1 [plasma membrane] (Homo sapiens)
as an input of
GRB7 binds phosphorylated heterodimer of ERBB2 and ERBB3 (Homo sapiens)
RNF41 binds neuregulin-activated ERBB3 (Homo sapiens)
Shc1 binds phosphorylated ERBB2:ERBB3 heterodimers (Homo sapiens)
Binding of PI3K to ERBB2:p-ERBB3 heterodimer (Homo sapiens)
Inferred To
Phosphorylated ERBB2:ERBB3 heterodimers [plasma membrane]
(Bos taurus)
Phosphorylated ERBB2:ERBB3 heterodimers [plasma membrane]
(Canis familiaris)
Phosphorylated ERBB2:ERBB3 heterodimers [plasma membrane]
(Danio rerio)
Phosphorylated ERBB2:ERBB3 heterodimers [plasma membrane]
(Drosophila melanogaster)
Phosphorylated ERBB2:ERBB3 heterodimers [plasma membrane]
(Gallus gallus)
Phosphorylated ERBB2:ERBB3 heterodimers [plasma membrane]
(Mus musculus)
Phosphorylated ERBB2:ERBB3 heterodimers [plasma membrane]
(Rattus norvegicus)
Phosphorylated ERBB2:ERBB3 heterodimers [plasma membrane]
(Sus scrofa)
Ghost homologue of Phosphorylated ERBB2:ERBB3 heterodimers [plasma membrane]
(Caenorhabditis elegans)
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