Reactome | POLR3C [nucleoplasm]

POLR3C [nucleoplasm]

Stable Identifier

R-HSA-1964430

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

HsRPC3, RPC3, DNA-directed RNA polymerase III subunit RPC3, DNA-directed RNA polymerase III subunit C, RPC62, RNA polymerase III 62 kDa subunit

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q9BUI4 POLR3C

Gene Names

POLR3C

Chain

chain:1-534

Reference Genes

BioGPS Gene:10623 POLR3C

COSMIC (genes):POLR3C POLR3C

CTD Gene:10623 POLR3C

dbSNP Gene:10623 POLR3C

ENSEMBL:ENSG00000186141.9 POLR3C

HGNC:30076 POLR3C

KEGG Gene (Homo sapiens):10623 POLR3C

Monarch:10623 POLR3C

NCBI Gene:10623 POLR3C

OMIM:617454 POLR3C

UCSC:Q9BUI4 POLR3C

Reference Transcript

Other Identifiers

0005130750

10623

11721549_a_at

11721550_x_at

11745254_a_at

16692135

209382_PM_at

209382_at

210573_PM_s_at

210573_s_at

2432657

2432658

2432659

2432660

2432661

2432662

2432663

2432664

2432665

2432666

2432667

2432669

2432671

2432673

2432675

2432676

2432678

2432679

2432682

2432683

2432686

2432688

2432689

2432690

2432691

2432692

2432694

2432695

34671_at

71470_at

782_at

7919226

A_24_P920271

A_33_P3273444

GE541510

GO:0000428

GO:0002376

GO:0003677

GO:0003697

GO:0003899

GO:0005515

GO:0005622

GO:0005634

GO:0005654

GO:0005666

GO:0005737

GO:0005829

GO:0006351

GO:0006355

GO:0006359

GO:0016740

GO:0032728

GO:0032991

GO:0043226

GO:0045087

GO:0045089

GO:0051607

GO:0098542

GO:0140098

HMNXSV003021803

ILMN_1795678

PH_hs_0032324

TC01003112.hg

U93867_at

g13325209_3p_a_at

g2228747_3p_at

Participates

as a component of

HsRPC6:HsRPC3:HsRPC7 [nucleoplasm] (Homo sapiens)

Other forms of this molecule

POLR3C [cytosol]

Inferred To

LOC107050951 [nucleoplasm] (Gallus gallus)

polr3c [nucleoplasm] (Danio rerio)

polr3c [nucleoplasm] (Dictyostelium discoideum)

POLR3C [nucleoplasm] (Bos taurus)

POLR3C [nucleoplasm] (Canis familiaris)

POLR3C [nucleoplasm] (Sus scrofa)

Polr3c [nucleoplasm] (Mus musculus)

Polr3c [nucleoplasm] (Rattus norvegicus)

RPC82 [nucleoplasm] (Saccharomyces cerevisiae)

Polr3C [nucleoplasm] (Drosophila melanogaster)

rpc82 [nucleoplasm] (Schizosaccharomyces pombe)

Cross References

RefSeq

NP_006459.3, NP_001290385.1

OpenTargets

ENSG00000186141

HPA

ENSG00000186141-POLR3C

GeneCards

Q9BUI4

Ensembl

ENSG00000186141, ENSP00000334564, ENST00000334163

PRO

Q9BUI4

Pharos - Targets

Q9BUI4

HMDB Protein

HMDBP11924

PDB

7D58, 7DN3, 7D59, 7FJJ, 7DU2, 2XUB, 7AST, 2XV4, 7AE3, 7AE1, 7FJI, 7A6H, 7AEA, 5AFQ

Interactors (8)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P14373 TRIM27	2	TRIM27 [nucleoplasm] (R-HSA-2997690) TRIM27 [cytosol] (R-HSA-8851002)	0.718	6
UniProt:P19388 POLR2E	2	POLR2E [nucleoplasm] (R-HSA-83713) POLR2E [cytosol] (R-HSA-1964438)	0.621	3
UniProt:Q08379 GOLGA2	3	p-S37-GOLGA2 [Golgi membrane] (R-HSA-2172179) GOLGA2 [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-HSA-2167933) GOLGA2 [Golgi membrane] (R-HSA-6808764)	0.556	3
UniProt:Q13464 ROCK1	6	ROCK1 [extracellular region] (R-HSA-6806527) ROCK1 [secretory granule lumen] (R-HSA-6804967) Activated ROCK1 [cytosol] (R-HSA-4687777) ROCK1(1114-1354) [cytosol] (R-HSA-212524) ROCK1(1-1113) [cytosol] (R-HSA-212523) ROCK1 [cytosol] (R-HSA-212509)	0.556	3
UniProt:Q12933 TRAF2	5	TRAF2 [nucleoplasm] (R-HSA-8862199) K63polyUb-TRAF2 [nucleoplasm] (R-HSA-8862194) K63polyUb-TRAF2 [cytosol] (R-HSA-8862193) PolyUb-TRAF2 [cytosol] (R-HSA-6782848) TRAF2 [cytosol] (R-HSA-66370)	0.556	3
UniProt:P26367 PAX6	1	PAX6 [nucleoplasm] (R-HSA-3009044)	0.556	3
UniProt:Q9NRD5 PICK1	2	PICK1 [plasma membrane] (R-HSA-416989) PICK1 [endocytic vesicle membrane] (R-HSA-417017)	0.556	3
UniProt:P52294 KPNA1	2	KPNA1 [cytosol] (R-HSA-180612) KPNA1 [nucleoplasm] (R-HSA-188865)	0.556	3

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