Reactome | Chondroitin can be sulfated on position 4 of GalNAc by CHST9, 11, 12 and 13

Chondroitin can be sulfated on position 4 of GalNAc by CHST9, 11, 12 and 13

Stable Identifier

R-HSA-1971483

Type

Reaction [transition]

Species

Homo sapiens

Compartment

Golgi membrane, Golgi lumen

ReviewStatus

5/5

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Chondroitin can be sulfated on position 4 of GalNAc by CHST9, 11, 12 and 13

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Carbohydrate sulfotransferase9, 11, 12 and 13 (CHST9, 11, 12 and 13) catalyse the transfer of sulfate from PAPS to position 4 of the N-acetylgalactosamine (GalNAc) residue of chondroitin (Kang et al. 2001, Okuda et al. 2000, Hiraoka et al. 2000, Kang et al. 2002 respectively).

Literature References

PubMed ID	Title	Journal	Year
11056388	Molecular cloning, expression, and chromosomal mapping of human chondroitin 4-sulfotransferase, whose expression pattern in human tissues is different from that of chondroitin 6-sulfotransferase Kuroiwa, A, Yamauchi, S, Yagi, F, Mita, S, Habuchi, O, Yamamori, D, Okuda, T, Matsuda, Y, Matsubara, T, Fukuta, M	J Biochem	2000
10781601	Molecular cloning and expression of two distinct human chondroitin 4-O-sulfotransferases that belong to the HNK-1 sulfotransferase gene family Fukuda, M, Nakagawa, H, Akama, TO, Ong, E, Fukuda, MN, Hiraoka, N	J Biol Chem	2000
12080076	Molecular cloning and characterization of chondroitin-4-O-sulfotransferase-3. A novel member of the HNK-1 family of sulfotransferases Evers, MR, Xia, G, Baenziger, JU, Schachner, M, Kang, HG	J Biol Chem	2002
11139592	Molecular cloning and expression of an N-acetylgalactosamine-4-O-sulfotransferase that transfers sulfate to terminal and non-terminal beta 1,4-linked N-acetylgalactosamine Evers, MR, Xia, G, Baenziger, JU, Schachner, M, Kang, HG	J Biol Chem	2001